Quality of Life After Minimally Invasive Endoscopic Surgery for Sinonasal and Anterior Skull Base Tumors.

Study ID
STU 012012-131

Cancer Related
No

Healthy Volunteers
No

Study Sites

  • Parkland Health & Hospital System
  • Parkland Health & Hospital System
  • UT Southwestern Ambulatory Services
  • UT Southwestern Ambulatory Services
  • UT Southwestern University Hospital– Zale Lipshy
  • UT Southwestern University Hospital– Zale Lipshy

Contact
Anna Bryan
214-648-2913
anna.bryan@utsouthwestern.edu

Principal Investigator
Sukhpreet Batra

Summary

This Study will measure the quality of life outcomes of [Double Quote]Skull Base Patients,[Double Quote] hereinafter defined as patients who have been treated for sinonasal and/or anterior skull base tumors at UT Southwestern and affiliated hospitals (Parkland and/or UT Southwestern University Hospital x Zale Lipshy) by faculty and/or clinicians of UT Southwestern[Right Quote]s Department of Otolaryngology-Head and Neck Surgery. The information gathered for this Study will be of two general types: (1) information from retrospective chart reviews of Skull Base Patients (2) information from the Anterior Skull Base Questionnaire (ASBQ) that Skull Base and the Euroqol EQ-5D survey patients will be requested to complete. Patients contacted by mail will also be asked to complete the Sinonasal Outcome Test-20 Questionnaire ([Double Quote]SNOT-20[Double Quote]). Patients being evaluated in clinic already fill this out to assess their ongoing sinonasal issues.
Skull Base Patients will be identified as described in the section [Double Quote]Study Procedures[Double Quote] found below. A retrospective review of charts from 1/1/2000 to 1/18/2012 of Skull Base Patients will be conducted. A maximum of 500 such charts will be assessed for such data as demographics, past medical history, symptoms, exam findings, prior treatment, complications, treatment modalities (e.g., chemotherapy, radiation therapy, type of surgical treatment), tumor characteristics, Lund-Kennedy Scores, Sino-Nasal Outcome Test-20 Questionnaire ([Double Quote]SNOT-20[Double Quote]) results, and radiographic findings (from CT, MRI, and/or PET scans, etc.).

A maximum of 500 Skull Base Patients will also be provided with a written consent form describing the Study and requesting their informed consent to complete the ASBQ and (for patients contacted by mail only) SNOT-20. Those providing their informed consent will complete the ASBQ (and SNOT-20, if applicable). Skull Base Patients who decline to provide their consent will not complete the ASBQ (and SNOT-20, if applicable) and will continue to receive optimal treatment that will not depend in any way on their decision to complete the form(s).

The data from the retrospective chart review, ASBQ, and (for patients contacted by mail only) SNOT-20 will be compiled and analyzed to better understand quality of life outcomes for patients with sinonasal and/or anterior skull base tumors.

Participant Eligibility

The following criteria for inclusion of subjects, not to exceed 500, will be used for the retrospective chart review:


* The patients have been treated by the principal investigator at UT Southwestern[Single Quote]s Department of Otolaryngology-Head and Neck Surgery;

* The patients were treated at UT Southwestern and affiliated hospitals (Parkland, and/or UT Southwestern University Hospital x Zale Lipshy) and are patients of the principal investigator;

* The patients were treated for sinonasal and/or anterior skull base tumors;

* The patients consulted with the faculty of UT Southwestern[Single Quote]s Department of Otolaryngology-Head and Neck Surgery at least one time between the dates of 1/1/2000 and 1/18/2012

* The patients have one or more of the following ICD9 codes associated with their treatment: 160.2; 160.3; 160.4; 160.5; 160.9; 212.0; 213.0 /or 239.1.

The following criteria for inclusion of subjects, not to exceed 500, will be used for the prospective ASBQ, the Euroqol EQ-5D, and (for patients contacted by mail only) SNOT-20:


* The patients have been treated by faculty and/or clinicians of UT Southwestern[Single Quote]s Department of Otolaryngology-Head and Neck Surgery;

* The patients were treated at UT Southwestern and affiliated hospitals (Parkland, and/or UT Southwestern University Hospital x Zale Lipshy);

* The patients were treated for sinonasal and/or anterior skull base tumors;

* The patients consulted with faculty and/or clinicians of UT Southwestern[Single Quote]s Department of Otolaryngology-Head and Neck Surgery at least one time between the dates of 1/1/2000 and 1/18/2012;

* The patients have one or more of the following ICD9 codes associated with their treatment: 160.2; 160.3; 160.4; 160.5; 160.9; 212.0; 213.0 /or 239.1;

* The patients provided their informed consent to complete the ASBQ, Euroqol EQ-5D (and SNOT-20, if applicable)

* The patients complete the ASBQ, Euroqol EQ-5D (and SNOT-20, if applicable).