A Feasibility Study of Optical Imaging-Guided Open-Face Mask Immobilization

Study ID
STU 102014-054

Cancer Related
Yes

Healthy Volunteers
No

Study Sites

  • Clements University Hospital
  • UT Southwestern Moncrieff Cancer Center

Contact
Asiya Siddiqui
214/648-5779
Asiya.Siddiqui@UTSouthwestern.edu

Principal Investigator
Bo Zhao, Ph.D.

Summary

up to 20 patients will be enrolled for this study. The patients will wear open-face mask system modified from FDa-approved and commercially available masking devices. testing will be performed retrospectively following delivery of standard-of-care treatment. Patient simulation computed tomography (CT) image set will be imported to Vision RT system. The imported information will include isocenter location and CT skin contours. The accuracy threshold of VisionRT will be set to 2 mm/2 degrees rotation. at the first day of treatment, the patient will be set up to surface markings, followed by VisionRT guidance. a cone-beam computed tomography (CBCT) will then be performed to verify the setup. The result of VisionRT will be examined using CBCT which provides 6D registration results.

Participant Eligibility

3.1.1 Any patient that has been diagnosed with head and neck cancer and is treated at UTSW Department of Radiation Oncology under CBCT-based image guided radiation therapy are eligible for this study.
3.1.2 Patients must be greater than or equal to 18 years of age. There are no gender or ethnic restrictions.
3.1.3 Life expectancy restrictions [?] None
3.1.4 ECOG or Karnofsky Performance Status [?] N/A
3.1.5 Requirements for organ and marrow function [?] None
3.1.6 Ability to understand and the willingness to sign a written informed consent document.
3.1.7 Women of child-bearing potential and men must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry, for the duration of study participation, and for 90 days following completion of therapy. Should a woman become pregnant or suspect she is pregnant while participating in this study, she should inform her treating physician immediately.