Compensatory Response Following Lung Resection

Study ID
STU 082014-020

Cancer Related
Yes

Healthy Volunteers
Yes

Study Sites

  • Clements University Hospital

Contact
Dan Dane
214/648-5675
dan.dane@utsouthwestern.edu

Principal Investigator
Connie Hsia, M.D.

Summary

Study design: Prospective cross-sectional (patient vs. control) and longitudinal (pre- vs. post-resection) data collection.
Subjects: The eligible patients (male or female, age [Greater Than]20 years) who require lung resection will be identified before undergoing surgery (segmentectomy, lobectomy, bilobectomy or pneumonectomy). Lung resection is most commonly performed for cancer, and infrequently for other indications (infection, trauma). Post-operatively, patients are routinely followed every 3 months for up to 2 years following lung resection surgery as part of standard clinical care. at each clinic visit, the medical records will be reviewed to extract the following data where available:
a) Semi-quantitative scores of symptoms and disability.
b) Blood and urine lab results.
c) Pulmonary function tests (spirometry, lung volumes, and DLCo, 6-minute walk test, transcutaneous o2 saturation.
d) Volumetric chest CT datasets x These will be analyzed to reconstruct airways, blood vessels [See protocol for complete text]

Participant Eligibility

Adults (male or female, age >20 years) who require surgical lung resection (segmentectomy, lobectomy, bilobectomy or pneumonectomy).