Correction of B0 inhomogeneity Induced by Orthodontic Appliances in MRI

Study ID
STU 032013-087

Cancer Related
No

Healthy Volunteers
No

Study Sites

  • Children’s Medical Center (Dallas, Plano, Southlake)

Contact
Zhiyue Wang
214/456-1479
JERRY.WANG@childrens.com

Principal Investigator
Zhiyue Wang, Ph.D.

Summary

This project aims to correct the MRi artifacts caused by dental bracket made by all vendors. The field correction device will be constructed by mounting small pieces of ndBFe permanent magnets on a mouth guard or on a face mask frame. Two layers of dental plastic and dental glue will be used to secure the magnets so they will not fall off from the device. Recently, a new intra-oral mouth guard design has been developed using 3D-printing with aBS plastic. Pieces with different magnetic moments will be assembled to match a wide range of induced magnetizations in orthodontic appliances. Subjects will come two groups. Group 1 is healthy subjects from local community who currently receive orthodontic treatment at CMC or elsewhere. The subject will undergo one session of brain MRi. in the first half of the session the subject will not wear the correction device. Depending on the results of the baseline B0 mapping, the device with the magnetic moment best matching the braces will be worn during the second half of the MRi session. Group 2 subjects will be recruited from patients undergoing clinically indicated brain MRi for headache or seizures. They are in neurologically sound condition to participate in the study. at the end of clinical MRi, a few short research scans will be added with the subject wearing a correction device. images will be analyzed to determine the effectiveness of the device in reducing MRi artifacts.
images will be evaluated by 2 radiologists. if one radiologist thinks an image scan is not satisfactory, the scan will be scored as unsatisfactory.

Participant Eligibility

Group 1: Patients who are (1) 11 or older and (2) treated with metal orthodontic brackets. (3) The patients are otherwise healthy without known neurologic disorders.
Group 2: Patients who are (1) 11 or older; (2) wearing metal orthondontic appliances; (3) receiving non-sedated brain MRI examination for head ache, minor closed head injury or seizure; (4) Neurologically sound and able to give assent to the study.