All Clinical Trials

* Metabolic Abnormalities in Patients with Inborn Errors of Cobalamin Metabolism[Double Quote]

A 12-Week, Randomized, Double-Blind, Controlled Evaluation Followed by an Open Label 12 Week Follow up Period of the Impact of GeneSight Psychotropic on Response to Psychotropic Treatment in Outpatients Suffering from a major Depressive Disorder (MDD) and having Had-Within the Current Episode-an Inadequate Response to at Least One Psychotropic Medication Included in GeneSight Psychotropic

A 2 Part, Phase III randomized, open label, multicenter study of LGX818 plus MEK162 versus vemurafenib and LGX818 monotherapy in patients with unresectable or metastatic BRAF V600 mutant melanoma

A Controlled Trial of Transcranial Direct Current Stimulation as a Treatment for Unipolar and Bipolar Depression.

A DOSE-RANGING STUDY OF THE EFFICACY AND SAFETY OF BARDOXOLONE METHYL IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION

A Double Blind, Randomized, Sham-Controlled Evaluation of Low-Level (Class IV) Therapeutic Laser Therapy on Plantar Fasciitis

A Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Patients with Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery Requiring Cardiopulmonary Bypass; LEVO-CTS

A Double-blind, Randomized, Placebo-controlled, Multicenter Study Assessing the Impact of Additional LDL-Cholesterol Reduction on Major Cardiovascular Events When AMG 145 is Used in Combination With Statin Therapy In Patients with Clinically Evident Cardiovascular Disease AMG 145 FOURIER (Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects With Elevated Risk)

A Long Term Follow-up Registry for Subjects Who Achieve a Sustained Virologic Response to Treatment in Gilead-Sponsored Trials in Subjects with Chronic Hepatitis C Infection (Protocol #: GS-US-248-0122: 13 April 2011)

A Long-Term Prospective Observational Safety Study of the Incidence of and Risk Factors for Fibrosing Colonopathy in US Patients with Cystic Fibrosis Treated with Pancreatic Enzyme Replacement Therapy: A Harmonized Protocol Across Sponsors

A Longitudinal Case-Control Study to Collect Clinical Data and Biologic Specimens for Research into Various Chronic Diseases

A Longitudinal Case-Control Study to Collect Clinical Data in Pediatric Central Nervous System Demyelinating Diseases

A Longitudinal Study of Patients Diagnosed With or at Increased Risk for Neuromyelitis Optica or Neuromyelitis Optica Spectrum Disorder

A Longitudinal Study to Identify and Validate Biomarkers from Serum and Cerebrospinal Fluid in Patients Evaluated by Neurologists

A Longitudinal, Case-Control Study to Collect Medical and Epidemiological Data and Blood Samples for Research Into the Causes of Multiple Sclerosis and Selected Demyelinating Diseases

A Multi Center, Post Approval Study Providing Continued Evaluation and Follow-up on Patients Who Received a HeartWare Ventricular Assist Device System During IDE Trials for the Treatment of Advanced Heart Failure

A Multi-Center Group to Study Acute Liver Failure

A Multi-Center Open-Label Phase I/2 Study of BGB324 in Combination with Erlotinib in Patients with Stage IIIb or Stage IV Non-Small Cell Lung Cancer

A Multi-Center Randomized Trial of Laparotomy vs. Drainage as the Initial Surgical Therapy for Extremely-Low-Birth-Weight (ELBW) Infants with Necrotizing Enterocolitis (NEC) or Isolated Intestinal Perforation (IP): Outcomes at 18-22 months Adjusted Age ( NEST-Necrotizing Enterocolitis Surgery Trial)

A Multi-Center, Open-Label, Continuation Trial of LymphoStat-B Antibody (Monoclonal Anti-BLyS Antibody) in Subjects with Systemic Lupus Erthematosus (SLE) Who Completed the Phase 2 Protocol LBSL02, Clinical Protocol LBSL99

A Multi-Center, Randomized, Controlled, Double-Blind Study of the Effects of an Antioxidant-Enriched Multivitamin Supplement on Inflammation and Oxidative Stress in Cystic Fibrosis Patients

A Multi-Institutional, Single Arm, Two-Stage Phase II Trial of Nab- Paclitaxel and Gemcitabine for First-Line Treatment of Patients with Advanced or Metastatic Cholangiocarcinoma

A Multi-arm Phase I Safety Study of Nivolumab in Combination with Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, Carboplatin/Paclitaxel, Bevacizumab Maintenance, Erlotinib, Ipilimumab or as Monotherapy in Subjects with Stage IIIB/IV Non-small Cell Lung Cancer (NSCLC)

A Multicenter Phase 1/2b Study of the Bruton[Single Quote]s Tyrosine Kinase Inhibitor, Ibrutinib (PCI-32765), in Combination with Carfilzomib (Kyprolis(TM)) in Subjects with Relapsed or Relapsed and Refractory Multiple Myeloma

A Multicenter Phase 2 Study of Single-agent Filanesib (ARRY-520) in Patients With Advanced Multiple Myeloma

A Multicenter Phase I Study of MRX34, MicroRNA miR-RX34 Liposomal Injection

A Multicenter Randomized Phase II Study of NPC-1C in Combination with Gemcitabine and nab-Paclitaxel versus Gemcitabine and nab-Paclitaxel alone in Patients with Metastatic or Locally Advanced Pancreatic Cancer Previously Treated with FOLFIRINOX

A Multicenter, Observational, Open-Label, Single-Arm Study of Tysabri in Early Relapsing-Remitting Multiple Sclerosis in Anti-JCV Antibody Negative Patients

A Multicenter, Parallel-group Study of Long-term Safety and Efficacy of CNTO 136 (sirukumab) for Rheumatoid Arthritis in Subjects Completing Treatment in CNTO136ARA3002 and CNTO136ARA3003

A Multicenter, Prospective, Long-Term, Observational Registry of Pediatric Patients with Inflammatory Bowel Disease

A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of the Safety and Efficacy of BMS-986020 in Subjects with Idiopathic Pulmonary Fibrosis (IM136003)

A Multicenter, Randomized, Double-Blind, Study Comparing the Efficacy and Safety of Continuing Versus Withdrawing Adalimumab Therapy in Maintaining Remission in Subjects with Non-Radiographic Axial Spondyloarthritis

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group Study of CNTO 136 (sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Subjects with Active Rheumatoid Arthritis Despite Anti-TNF(RegisteredTM) Therapy

A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group Study of CNTO 136 (sirukumab), a Human Anti-IL-6 Monoclonal Antibody, Administered Subcutaneously, in Subjects with Active Rheumatoid Arthritis Despite DMARD Therapy

A Multicenter, randomized, partial-blinded, placebo-controlled study to evaluate the safety and efficacy of a human plasma derived Alpha1-proteinase inhibitor in subjects with new onset type 1 diabetes mellitus

A Multicentre Randomised Phase II Study of AZD1775 plus Chemotherapy versus Chemotherapy Alone in Patients with Platinum-Resistant TP53- Mutated Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

A Multicentre, Randomised, Placebo-controlled, Double-blind Study of the Efficacy, Safety, and Pharmacokinetics of Lubiprostone in Paediatric Subjects Aged >= 6 Years to < 18 Years with Functional Constipation (Protocol: SAG/0211PFC-1131)

A Multinational, Randomised, Double-Blind, Placebo-Controlled Trial to Evaluate the Effect of Ticagrelor 90 mg twice daily on the Incidence of Cardiovascular Death, Myocardial Infarction or Stroke in Patients with Type 2 Diabetes Mellitus.

A Novel Approach To Exploring The Impact of Various Nursing Interventions In Critical Care (NATIVe)

A PHASE 3 OPEN-LABEL RANDOMIZED STUDY OF QUIZARTINIB (AC220) MONOTHERAPY VERSUS SALVAGE CHEMOTHERAPY IN SUBJECTS WITH FLT3-ITD POSITIVE ACUTE MYELOID LEUKEMIA (AML) REFRACTORY TO OR RELAPSED AFTER FIRST-LINE TREATMENT WITH OR WITHOUT HEMATOPOIETIC STEM CELL TRANSPLANTATION (HSCT) CONSOLIDATION

A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO COMPARE EFFICACY AND SAFETY OF ORAL AZACITIDINE PLUS BEST SUPPORTIVE CARE VERSUS BEST SUPPORTIVE CARE AS MAINTENANCE THERAPY IN SUBJECTS WITH ACUTE MYLOID LEUKEMIA IN COMPLETE REMISSION

A PHASE II RANDOMIZED, DOUBLE-BLIND, PLACEBO[?] CONTROLLED, MULTICENTER STUDY OF VS-6063 IN SUBJECTS WITH MALIGNANT PLEURAL MESOTHELIOMA

A PHASE II STUDY OF PNT2258 IN PATIENTS WITH RELAPSED OR REFRACTORY DIFFUSE LARGE B-CELL LYMPHOMA

A PHASE IV STUDY TO EVALUATE THE PHARMACOKINETICS AND SAFETY OF OXYCODONE ORAL SOLUTION IN PEDIATRIC AND ADOLESCENT SUBJECTS

A Phase 1 Study of Substance P-Saporin with Histologically Confirmed Advanced Cancer Patients with Chronic Pain

A Phase 1 Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493, a pan-Fibroblast Growth Factor Receptor (FGFR) Tyrosine Kinase Inhibitor, in Subjects With Advanced or Refractory Solid Tumors or Lymphoma

A Phase 1 Study to Evaluate the Safety, Tolerability,Pharmacokinetics, and Pharmacodynamics of GS-5745 as Monotherapy and in Combination with Chemotherapy in Subjects with Advanced Solid Tumors

A Phase 1, First-In-Human Study of Escalating Doses Of Oral TVB-2640 in Patients with Solid Tumors

A Phase 1, Multicenter, Open-Label, Dose-Escalation and Expansion, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-120 in Subjects with Advanced Hematologic Malignancies with an IDH1 Mutation

A Phase 1, Multicenter, Open-Label, Dose-Escalation and Expansion, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-221 in Subjects with Advanced Hematologic Malignancies with an IDH2 Mutation

A Phase 1-2 Dose Escalation Study Evaluating Safety and Feasibility of BPX-501 T Cells after Partially Mismatched, Related, T Cell-Depleted HSCT

A Phase 1/2, Multicenter, Open-Label, Dose-Escalation Study of AG-221 in Subjects with Advanced Solid Tumors, including Glioma, and with Angioimmunoblastic T-cell Lymphoma, that Harbor an IDH2 Mutation

A Phase 1B Clinical Trial of Trametinib plus Digoxin in Patients with Unresectable or Metastatic BRAF wild-type Melanoma

A Phase 1B Dose Escalation Study to Investigate the Safety, Tolerability and Preliminary Efficacy for the Combination of Dasatinib (BMS-354825) plus Nivolumab (BMS-936558) in Patients with Chronic Myeloid Leukemia (CML)

A Phase 1B Open-Label, Dose-Escalation Study Of The Safety, Tolerability, And Pharmacokinetics Of MEHD7945a And Cobimetinib In Patients With Locally Advanced Or Metastatic Cancers With Mutant KRAS

A Phase 1b Multicenter, Open-Label, Dose-Escalation Study To Determine The Maximum Tolerated Dose, Safety, And Antitumor Activity Of An Alternative Liquid Formulation Of Acy-1215 (Ricolinostat) In Combination With Pomalidomide And Low-Dose Dexamethasone In Patients With Relapsed or Relapsed-And-Refractory Multiple Myeloma

A Phase 2, Multi-center Study To Evaluate Four Doses Of NGM282 Administered For 52 Weeks In Patients With Primary Biliary Cirrhosis (PBC)

A Phase 2, Open-Label, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Efficacy of FG-3019 in Subjects with Idiopathic Pulmonary Fibrosis

A Phase 2, Placebo Controlled, Double-Blind, Randomized, Clinical Study to Determine Safety, Tolerability and Efficacy of Pulsed, Inhaled Nitric Oxide (iNO) Versus Placebo as Add-On Therapy in Symptomatic Subjects With Pulmonary Arterial Hypertension (PAH)

A Phase 2/3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of GS-6615 on Exercise Capacity in Subjects with Symptomatic Hypertrophic Cardiomyopathy

A Phase 2a Study to Evaluate the Safety and Tolerability of OCR-002 (ornithine phenylacetate) in the Treatment of Patients with Acute Liver Failure/Severe Acute Liver Injury (STOP-ALF)

A Phase 2b, Dose-Ranging, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Safety and Efficacy of GS-6624,a Monoclonal Antibody Against Lysyl Oxidase Like 2 (LOXL2) in Subjects with Primary Sclerosing Cholangitis (PSC)

A Phase 3 Extension Study of Ataluren (PTC124) in Patients with Nonsense Mutation Dystrophinopathy

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of BMS-188667 (Abatacept) or Placebo on a Background of Mycophenolate Mofetil (MMF) and Corticosteroids in Subjects with Active Class III or IV Lupus Nephritis

A Phase 3 Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of Pyridorin(TM) (pyridoxamine dihydrochloride) in Subjects With Nephropathy Due to Type 2 Diabetes

A Phase 3, 12-week, Double-Blind, Placebo-Controlled, Randomized, Multicenter Study to Evaluate the Efficacy of Oral Istradefylline 20 and 40 mg/day as Treatment for Subjects with Moderate to Severe Parkinson[Single Quote]s Disease

A Phase 3, Multi-Center, open-Label Study of a Levonorgestrel-Releasing Intrauterine System for Long-Term, Reversible contraception

A Phase 3, Multicenter, Open-Label, Randomized Study of nab(RegisteredTM)-Paclitaxel Plus Gemcitabine Versus Gemcitabine Alone as Adjuvant Therapy in Subjects with Surgically Resected Pancreatic Adenocarcinoma

A Phase 3, Multicenter, Randomized, Open-label Study to Compare the Efficacy and Safety of Pomalidomide (POM), Bortezomib (BTZ) and Low-Dose Dexamethasone (LD-DEX) versus Bortezomib and Low-Dose Dexamethasone in Subjects with Relapsed or Refractory Multiple Myeloma (MM)

A Phase 3, Open-Label, Multicenter Study to Evaluate the Safety of Paricalcitol Capsules in Pediatric Subjects Ages 10 to 16 with Stage 5 Chronic Kidney Disease Receiving Peritoneal Dialysis or Hemodialysis

A Phase 3, Randomized, Active Comparator, Double-Blind, Multi-Center Study to Compare the Efficacy, Safety and Tolerability of ITCA 650 to Sitagliptin as Add-on Therapy to Metformin in Patients with Type 2 Diabetes. ITCA 650-CLP-105

A Phase 3, Randomized, Controlled, Open-label, Multicenter, Safety and Efficacy Study of Dexamethasone Plus MLN9708 or Physician's Choice of Treatment Administered to Patients With Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Efficacy, Safety and Tolerability of ITCA 650 in Patients with Type 2 Diabetes. ITCA 650-CLP-103

A Phase 3, Randomized, Double-Blind, Sham-Procedure Controlled Study to Assess the Clinical Efficacy and Safety of ISIS 396443 Administered Intrathecally in Patients with Infantile-onset Spinal Muscular Atrophy

A Phase 3, Randomized, Double-blind, Sham-Procedure Controlled Study to Assess the Clinical Efficacy and Safety of ISIS 396443 Administered Intrathecally in Patients with Later-onset Spinal Muscular Atrophy

A Phase 3, Randomized, Open-Label Study of Nivolumab Combined with Ipilimumab Versus Sunitinib Monotherapy in Subjects with Previously Untreated, Advanced or Metastatic Renal Cell Carcinoma

A Phase 3, Safety and Efficacy Study of Boceprevir/Peginterferon Alfa-2a/ribavirin in Chronic HCV Genotype 1 IL28B CC Subjects

A Phase 3, Two-Arm, Rollover Study to Evaluate the Safety of Long-Term Ivacaftor Treatment in Subjects 6 Years of Age and Older with Cystic Fibrosis and a Non-G551D CFTR Mutation

A Phase 3/4, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, 52-Week Study to Evaluate the Efficacy and Safety of Belimumab (HGS1006) in Adult Subjects of Black Race with Systemic Lupus Erythematosus (SLE).

A Phase 3b, Multicenter, Open-Label Study to Evaluate the Long-Term Safety and Efficacy of Subcutaneous LY2127399 in Patients with Systemic Lupus Erythematosus (SLE) (ILLUMINATE-X) H9B-MC-BCDX(a)

A Phase 4 Multi-center, Ascending Dose, Open Label Study to Determine the Pharmacokinetics of Phenylephrine and the Pharmacodynamic Effects on Blood Pressure following Intravenous Administration of Phenylephrine Hydrochloride Injection, USP in Pediatric Subjects (>=12 to 16 years of age) Undergoing General and Neuroaxial Anesthesia

A Phase 4, Open-Label Study of the Pharmacokinetics and Safety of Diclofenac Potassium Oral Solution in Pediatric Subjects (Ages 2-12) with Mild to Moderate Acute Pain

A Phase I CyberKnife Accelerated Hemilarynx Stereotactic Radiotherapy Study for Early-stage Glottic Larynx Cancer

A Phase I Open-label, Dose Escalation Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Clinical Activity of the Antibody Drug Conjugate GSK2857916 in Subjects with Relapsed/Refractory Multiple Myeloma and Other Advanced Hematologic Malignancies Expressing BCMA

A Phase I Study of Cyberknife(RegisteredTM) Partial Breast Irradiation (PBI) for Early Stage Breast Cancer

A Phase I Study of Reduced-Volume Hypofractionated, PET-directed Intensity Modulated Radiotherapy Concurrent with Weekly Cisplatin Chemotherapy for T1/2N0-2 Squamous Cell Carcinoma of the Head and Neck

A Phase I Study of the Phosphatidylserine-Targeting Antibody Bavituximab in Combination with Capecitabine and Radiation Therapy for the Treatment of Stage II and III Rectal Adenocarcinoma

A Phase I Trial of Stereotactic HYpofractionateD RadioAblative (HYDRA) Treatment of Advanced Laryngeal Cancer

A Phase I dose escalation study of ARQ 761 (Beta-Lapachone) in adult patients with advanced solid tumors

A Phase I open-label study of the safety and pharmacokinetics of escalating doses of DNIB0600A in patients with non-small cell lung cancer and platinum-resistant ovarian cancer

A Phase II Study for Image Guided Hypofractionated Radiation Boost Therapy for Definitive Treatment of Locally Advanced Cervical Cancer

A Phase II Study of Pioglitazone for patients with cancer of the pancreas

A Phase II Study of Sirolimus and Erlotinib in Recurrent/Refractory Germ Cell Tumors

A Phase II Trial of High Dose IL-2 and Stereotactic Ablative Body Radiation Therapy (SABR) for Patients with Metastatic Clear Cell Renal Cell Cancer (mRCC)

A Phase II Trial of Losartan to Reverse Sickle Nephropathy

A Phase II Trial of Rituximab In Myasthenia Gravis (NN103)

A Phase III Clinical Trial to Study the Safety and Efficacy of MK-1293 Compared to Lantus[?] in Subjects With Type 1 Diabetes Mellitus; MK 1293-003-02

A Phase III Double Blind Clinical Trial to Study the Efficacy and Safety of the Combination Regimen of MK-5172 and MK-8742 in Subjects with Chronic HCV GT1, GT4 and GT6 Infection with Inherited Blood Disorders with and without HIV Co-Infection

A Phase III Open-LabelRandomized Clinical Trial to Study the Efficacy and Safety of the Combination Regimen of MK-5172/MK-8742 in Treatment-Naive Subjects with Chronic HCV GT1, GT4, GT5, and GT6 Infection who are on Opiate Substitution Therapy.

A Phase III Randomized Clinical Trial to Study the Efficacy and Safety of the Combination Regimen of MK-5172/MK-8742 in Treatment-Naive Subjects with Chronic HCV GT1, GT4, GT5, and GT6 Infection.

A Phase III Study of Chemotherapy With or Without Algenpantucel-L (HyperAcute(RegisteredTM)- Pancreas) Immunotherapy in Subjects with Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer

A Phase III Surgical Trial to Evaluate the Benefit of a Standard versus an Extended Pelvic Lymphadenectomy Performed at Time of Radical Cystectomy for Muscle Invasive Urothelial Cancer

A Phase III, Multinational, Multicenter, Randomized, Double-Blind, Parallel-Group, Sham-Controlled Study to Evaluate the Safety, Tolerability and Efficacy of aCureXCell(TM) as an Adjunct to Good Wound Care Measures in Treating Lower Extremity Chronic Ulcers in Adults with Diabetes Mellitus

A Phase III, multicentre, randomized, parallel-group, double blinded, placebo controlled study to evaluate the efficacy and safety of Ocrelizumab in adults with Primary Progressive Multiple Sclerosis

A Phase IIIb, randomized, open-label study of the safety and efficacy of dolutegravir/abacavir/lamivudine once daily compared to atazanavir and ritonavir plus tenofovir/emtricitabine once daily in HIV-1 infected antiretroviral therapy naive women

A Phase IIIb, randomized, open-label study of the safety, efficacy, and tolerability of switching to a fixed-dose combination of abacavir/dolutegravir/ lamivudine from current antiretroviral regimen compared with continuation of the current antiretroviral regimen in HIV-1 infected adults who are virologically suppressed

A Phase IV Prospective, Multi-Center, Randomized, Single-Blind, Active and Standard Care-Controlled Clinical Investigation of DermaPure in Patients with Hard to Heal Chronic, Neuropathic Diabetic Foot Ulcers with Crossover Design for Standard Care Arm (TRG-H01-01)

A Phase IV Trial of Neuroprotection with ACTH in Acute Optic Neuritis

A Phase IV, multicenter, prospective, randomized, controlled clinical study to compare the IrriSept system versus Standard of Care (SoC) on the prevalence of Surgical Site Infection (SSI) in patients with abdominal trauma or acute surgical abdomen

A Pilot Study of * OncozeneTM * Microspheres for intra-arterial delivery of doxorubicin for the treatment of patients with unresectable hepatocellular cancer

A Proof of Concept Study of Icariin for Bipolar Disorder and Co-Occurring Substance Use Disorders

A Prospective , Double-Blind, Randomized, Controlled Trial to Evaluate the Safety and Efficacy of the H-Coil Deep Transcranial Magnetic Stimulation (TMS) in Conjunction with Mood Stabilizers in Subject with Bipolar Depression

A Prospective Randomized Trial to Assess Fixation Strategies for Severe Open Tibia Fractures Modern Ring External Fixators vs. Internal Fixation (FIXIT Study)

A Prospective, Multi-center Trial of NovoTTF-100A Together With Temozolomide Compared to Temozolomide Alone in Patients with Newly Diagnosed GBM

A Prospective, Randomized Investigation of Syndesmosis Injury Fixation

A Prospective, Randomized, Controlled Multicenter Clinical Study to Evaluate the Safety and Effectiveness of the IBV(RegisteredTM) Valve System for the Single-Lobe Treatment of Severe Emphysema (EMPROVE)

A Prospective, Randomized, Controlled, Un-blinded, Multi-Center Clinical Trial to Evaluate the HeartWare(RegisteredTM) Ventricular Assist System for Destination Therapy of Advanced Heart Failure

A Prospective, Randomized, Multi-Center Trial Evaluating the Effectiveness of the V.A.C.Ulta(TM) Negative Pressure Wound Therapy System with V.A.C. VeraFlo(TM) Dressing System in Operatively Debrided Wounds

A RANDOMIZED PHASE I/II STUDY OF NAB-PACLITAXEL, OR PACLITAXEL, PLUS CARBOPLATIN WITH CONCURRENT RADIATION THERAPY FOLLOWED BY CONSOLIDATION IN PATIENTS WITH FAVORABLE PROGNOSIS INOPERABLE STAGE IIIA/B NON-SMALL CELL LUNG CANCER (NSCLC)

A RANDOMIZED, PHASE 3 STUDY OF GANETESPIB IN COMBINATION WITH DOCETAXEL VERSUS DOCETAXEL ALONE IN PATIENTS WITH ADVANCED NON-SMALL-CELL LUNG ADENOCARCINOMA

A Randomized Controlled Clinical Trial of Treatment of Mild Gestational Diabetes with Glyburide versus Placebo

A Randomized Controlled Phase 3 Study of Oral Pacritinib versus Best Available Therapy in Patients with Thrombocytopenia and Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis

A Randomized Controlled Trial of The Effect of Hydrocortisone on Survival Without Bronchopulmonary Dysplasia and on Neurodevelopmental Outcomes at 22-26 Months of Age in Intubated Infants <30 Weeks Gestational Age

A Randomized Double Blind, Placebo Controlled, Phase 3 Trial of Tadalafil for Duchenne Muscular Dystrophy

A Randomized Phase III Study Comparing Conventional Dose Treatment Using a Combination of Lenalidomide, Bortezomib and Dexamethasone (RVD) to High-Dose Treatment with Peripheral Stem Cell Transplant in the Initial Management of Myeloma in Patients up to 65 Years of Age.

A Randomized Pilot Study Assessing Vagus Nerve Stimulation (VNS) During Rehabilitation for Improved Upper Limb Motor Function after Stroke

A Randomized Placebo-Controlled Study of Lovastatin in Children with Neurofibromatosis Type 1

A Randomized Trial to Prevent Congenital Cytomegalovirus (CMV)

A Randomized, Blinded Clinical Evaluation of Efficacy and Safety of Intensive Repair and Protect Vitamin C for Scar Reduction in Subjects with Unilateral or Bilateral Surgery Scars

A Randomized, Controlled, Open Label Trial Comparing the Ischemic Preconditioning Effects of Ticagrelor and Clopidogrel in Humans

A Randomized, Double-Blind Study of Ruxolitinib or Placebo in Combination With Regorafenib in Subjects With Relapsed or Refractory Metastatic Colorectal Cancer

A Randomized, Double-Blind, Double-Dummy, Parallel-Group Study To Evaluate The Efficacy And Safety Of Ocrelizumab In Comparison To Interferon Beta-1a (Rebif(RegisteredTM)) In Patients With Relapsing Multiple Sclerosis

A Randomized, Double-Blind, Multicenter, Superiority, Placebo-Controlled Phase 3 Study of Pexiganan Cream 0.8% Applied Twice Daily for 14 Days in the Treatment of Adults with Mild Infections of Diabetic Foot Ulcers

A Randomized, Double-Blind, Phase III Study of the Efficacy and Safety of Gemcitabine in Combination With TH-302 Compared With Gemcitabine in Combination With Placebo in Previously Untreated Subjects With Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma

A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of IPI-145 in Combination with Rituximab vs Rituximab in Subjects with Previously-Treated Follicular Lymphoma

A Randomized, Double-Blind, Placebo-Controlled Study comparing CroFab(RegisteredTM) versus Placebo with Rescue Treatment for Copperhead Snake Envenomation

A Randomized, Double-Blind, Placebo-Controlled Study of Chemotherapy Plus Cetuximab in Combination with VTX-2337 in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of Eculizumab in subjectS with Refractory Generalized Myasthenia Gravis (gMG)

A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Safety and Efficacy of P-1037 Solution for Inhalation in Patients with Cystic Fibrosis

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study of Ibrutinib or Placebo in Combination With Rituximab in Subjects with Waldenstr[?]m[Single Quote]s Macroglobulinemia

A Randomized, Double-Blind, Vehicle-Controlled, Multicenter Safety and Efficacy Study of a Single Intraprostatic Treatment of PRX302 for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia (The PLUS 1 Trial)

A Randomized, Double-blind, Event-driven, Placebo-controlled, Multicenter Study of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Subjects With Type 2 Diabetes Mellitus and Diabetic Nephropathy The CREDENCETM Trial(Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation Trial)

A Randomized, Multi-Center, Pivotal Efficacy and Safety Study Comparing the EndoBarrier [?] Gastrointestinal Liner System vs. Sham for Glycemic Improvement in Inadequately Controlled Obese Type 2 Diabetic Subjects on Metformin and/or Sulfonylurea Anti-Diabetes Agents

A Randomized, Multi-site, Parallel-group, Rater-blind Study Comparing Response with Aripiprazole Once Monthly and Standard of Care Oral Antipsychotics in Non-adherent Outpatients with Schizophrenia Identified using the Brief Adherence Rating Scale

A Randomized, Open-Label Study Comparing the Combination of YONDELIS(RegisteredTM) and DOXIL(RegisteredTM)/CAELYX(RegisteredTM) With DOXIL(RegisteredTM)/CAELYX(RegisteredTM) Monotherapy for the Treatment of Advanced-Relapsed Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

A Randomized, Open-Label, Multicenter, Phase 3 Trial Comparing Veliparib Plus Carboplatin and Paclitaxel Versus Investigator's Choice of Standard Chemotherapy in Subjects Receiving First Cytotoxic Chemotherapy for Metastatic or Advanced Non-Squamous Non-Small Cell Lung Cancer (NSCLC) and Who Are Current or Former Smokers

A Randomized, Open-label Study to Evaluate the Safety and Efficacy of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 Coadministered with Ribavirin (RBV) in Adults with Genotype 1 Chronic Hepatitis C Virus (HCV) Infection and Human Immunodeficiency Virus, Type 1 (HIV-1) Coinfection (TURQUOISE-I)

A Randomized, Placebo Controlled, Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Intravenous (IV) Acetaminophen for the Treatment of Acute Pain in Pediatric Patients

A Randomized, Placebo-Controlled, Double-Blind,Phase 3 Study Evaluating Safety and Efficacy of the Addition of Veliparib Plus Carboplatin Versus the Addition of Carboplatin to Standard Neoadjuvant Chemotherapy Versus Standard Neoadjuvant Chemotherapy in Subjects with Early Stage Triple Negative Breast Cancer (TNBC)

A Research Depository of Normal and Neoplastic Human Tissues

A STUDY OF NERATINIB PLUS CAPECITABINE VERSUS LAPATINIB PLUS CAPECITABINE IN PATIENTS WITH HER2+ METASTATIC BREAST CANCER WHO HAVE RECEIVED TWO OR MORE PRIOR HER2-DIRECTED REGIMENS IN THE METASTATIC SETTING (NALA)

A Safety and Tolerability Trial of Crenolanib and Chemotherapy with Cytarabine and Anthracyclines in Patients with Newly Diagnosed Acute Myeloid Leukemia with FLT3 Activating Mutations

A Search for Optimally Bioavailable Calcium-Magnesium Supplement with Reduced Cardiovascular Risk

A Study of Physical and Metabolic Abnormalities in Patients with Lipodystrophy and Dyslipidemias and Their Relatives

A Two-Arm, Single Center Phase IB Trial of Bavituximab plus Ipilimumab in Advanced Melanoma Patients

A case controlled study comparing analgesia after cesarean delivery using continuous epidural opioid versus parenteral opioid analgesia.

A comparison of anatomic relationships and description of central venous access sites in pediatric patients

A long-term, randomised, double-blind, placebo-controlled, multinational, multi-centre trial to evaluate cardiovascular and other long-term outcomes with semaglutide in subjects with type 2 diabetes

A multi-center sub-study to validate the CDAD-DaySyms (Clostridium difficile-associated diarrhea x Daily Symptoms) PRO in subjects with CDAD participating in study AC-061A301 or AC-061A302

A multi-center, randomized, double-blind study to compare the efficacy and safety of cadazolid versus vancomycin in subjects with Clostridium difficile associated diarrhea

A multicenter safety study of unlicensed investigational cryopreserved cord blood units (CBUs) manufactured by the National Cord Blood Program (NCBP) and provided for unrelated hematopoietic stem cell transplantation of pediatric and adult patients

A multicenter, double-blind, randomized, placebo-controlled, Phase 3 study to assess the efficacy and safety of oral BPS-314d-MR added-on to treprostinil, inhaled (Tyvaso(RegisteredTM)) in subjects with pulmonary arterial hypertension

A phase 2, open-label, clinical trial of fluoxetine, a selective serotonin reuptake inhibitor, in the treatment of pulmonary arterial hypertension

A phase 2, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of FG-3019 in patients with idiopathic pulmonary fibrosis

A phase I, open-label study of anti-inflammatory therapy with rilonacept in adolescents and adults with type 1 diabetes mellitus

A phase III randomized double blind study of dabrafenib (GSK2118436) in COMBInation with trametinib(GSK1120212) versus two placebos in the ADjuvant treatment of high-risk BRAF V600 mutation-positive melanoma after surgical resection

A phase III randomized, double blind, placebo controlled study of BKM120 with fulvestrant, in postmenopausal women with hormone receptor-positive HER2-negative AI treated, locally advanced or metastatic breast cancer who progressed on or after mTOR inhibitor based treatment-(BKM 120-2303)

A randomized Trial of Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis in The Emergency Department

A randomized, double-blind, placebo-controlled phase II study to investigate the efficacy and safety of riociguat (0.5 mg, 1.0 mg, 1.5 mg, 2.0 mg and 2.5 mg TID) in patients with symptomatic pulmonary hypertension associated with idiopathic interstitial pneumonias (IIP).

A randomized, double-blind, placebo-controlled study of secukinumab to demonstrate the efficacy at 24 weeks and to assess the safety, tolerability and long term efficacy up to 2 years in patients with active rheumatoid arthritis who have an inadequate response to anti-TNF(RegisteredTM) agents

A randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of different doses of BYM338 on lean body mass, function and mobility in patients with sporadic inclusion body myositis.

A randomized, double-blind, placebo-controlled, ascending single-dose study of the safety, tolerability, and bioeffect of subcutaneously or intravenously administered R1500

A retrospective review of toxicities in intermediate risk rhabdomyosarcoma patients treated on ARST0531

A single-arm, open label, multicenter Phase 3 study of the contraceptive efficacy, safety and tolerability of the AG200-15 transdermal contraceptive delivery system (TCDS)

A single-center, double-blinded, randomized, 12 week, superiority study in infants and young children to compare the efficacy of NovaFerrum(RegisteredTM) versus Ferrous Sulfate in the treatment of nutritional iron deficiency anemia (BESTIRON).

A trial comparing cardiovascular safety of insulin degludec versus insulin glargine in subjects with type 2 diabetes at high risk of cardiovascular events

A011106: ALTernate approaches for clinical stage II or III Estrogen Receptor positive breast cancer NeoAdjuvant TrEatment (ALTERNATE) in postmenopausal women: A Phase III Study

A011202: A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients (cT1-3N1) Who Have Positive sentinel Lymph Node Disease after Neoadjuvant Chemotherapy

A031201: PHASE III TRIAL OF ENZALUTAMIDE (NSC # 766085) VERSUS ENZALUTAMIDE, ABIRATERONE AND PREDNISONE FOR CASTRATION RESISTANT METASTATIC PROSTATE CANCER

A041202: A RANDOMIZED PHASE III STUDY OF BENDAMUSTINE PLUS RITUXIMAB VERSUS IBRUTINIB PLUS RITUXIMAB VERSUS IBRUTINIB ALONE IN UNTREATED OLDER PATIENTS (>= 65 YEARS OF AGE) WITH CHRONIC LYMPHOCYTIC LEUKEMIA (CLL)

A081105:RANDOMIZED DOUBLE BLIND PLACEBO CONTROLLED STUDY OF ERLOTINIB OR PLACEBO IN PATIENTS WITH COMPLETELY RESECTED EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) MUTANT NON-SMALL CELL LUNG CANCER (NSCLC)

A091201: RANDOMIZED PHASE II STUDY COMPARING THE MET INHIBITOR CABOZANTINIB TO TEMOZOLOMIDE/DACARBAZINE IN OCULAR MELANOMA

A151216: Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST)

AALL1122, A Phase 2 Multi-Center Historically - Controlled Study of Dasatinib Added to Standard Chemotherapy in Pediatric Patients with Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)

AALL1131, A Phase III Randomized Trial for Newly Diagnosed High Risk B-precursor Acute Lymphoblastic Leukemia (ALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum

AALL1231, A Phase III Randomized Trial Investigating Bortezomib (NSC# 681239; IND# 58443) on a Modified Augmented BFM (ABFM) Backbone in Newly Diagnosed T-Lymphoblastic Leukemia (T-ALL) and T-Lymphoblastic Lymphoma (T-LLy)

AAML08B1, Biology Study of Transient Myeloproliferative Disorder (TMD) in Children with Down Syndrome (DS)

AAML1031, A Phase III Randomized Trial for Patients with de novo AML using Bortezomib and Sorafenib (IND#114480; NSC# 681239, NSC# 724772) for Patients with High Allelic Ratio FLT3/ITD

AAML1321 (CAMN1072203), A Multi-Center, Open Label, Non-Controlled Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Pediatric Patients with Newly Diagnosed Ph+ Chronic Myelogenous Leukemia (CML) in Chronic Phase (CP) or with Ph+ CML in CP or Accelerated Phase (AP) Resistant or Intolerant to either Imatinib or Dasatinib

AC-065A303 (GRIPHON OL), Long-term single-arm open-label study, to assess the safety and tolerability of ACT-293987 in patients with pulmonary arterial hypertension

ACCL0922, (SCUSF 0901) A Phase II Placebo-Controlled Trial of Modafinil to Improve Neurocognitive Deficits in Children Treated for a Primary Brain Tumor

ACCL0933, A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infections in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML)

ACCL1033, A Comprehensive Approach to Improve Medication Adherence in Pediatric ALL

ACCL10P1, Computerized Cognitive Training for Pediatric Brain Tumor Patients: A Pilot Study

ACCL1131, A Phase III Open-Label Trial of Caspofungin vs. Azole Prophylaxis for Patients at High-Risk for Invasive Fungal Infections (IFI) Following Allogeneic Hematopoietic Cell Transplantation (HCT)

ACNS0331: A Study Evaluating Limited Target Volume Boost Irradiation and Reduced Dose Craniospinal Radiotherapy (18 Gy) and Chemotherapy in Children with Newly Diagnosed Standard Risk Medulloblastoma: A Phase III Double Randomized Trial

ACNS0821, Temozolomide with Irinotecan Versus Temozolomide, Irinotecan plus Bevacizumab for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood, A COG Randomized Phase II Screening Trial

ACNS1022, A Phase II Randomized Trial of Lenalidomide (NSC # 703813, IND # 70116) in Pediatric Patients with Recurrent, Refractory or Progressive Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas

ACNS1123, Phase 2 Trial of Response-Based Radiation Therapy for Patients with Localized Central Nervous System Germ Cell Tumors

ACOSOG Z11102 Impact of Breast Conservation Surgery on Surgical Outcomes and Cosmesis in Patients with Multiple Ipsilateral Breast Cancers (MIBC)

ADVL1322 (GSK VEG116731), A Phase II Study of Pazopanib GW786034, NSC# 737754 in Children, Adolescents and Young Adults with Refractory Solid Tumors

AEWS1221, Randomized Phase II Trial Evaluating the Addition of the IGF-1R Monoclonal Antibody Ganitumab (NSC# 750008, IND# 120449) to Multiagent Chemotherapy for Patients with Newly Diagnosed Metastatic Ewing Sarcoma

AHOD1331, A Randomized Phase III Study of Brentuximab Vedotin (SGN-35, IND #117117) for Newly Diagnosed High-Risk Classical Hodgkin Lymphoma (cHL) in Children and Adolescents

ALTE05N1, Umbrella Long-Term Follow-up Protocol

ALTE07C1, Neuropsychological, Social, Emotional, and Behavioral Outcomes in Children with Cancer

ALTE11C1, Longitudinal Assessment of Ovarian Reserve in Adolescents with Lymphoma

ALTE11C2, Health Effects after Anthracycline and Radiation Therapy (HEART): Dexrazoxane and Prevention of Anthracycline-related Cardiomyopathy

ALZHEIMER'S DISEASE NEUROIMAGING INITIATIVE 2 (ADNI2) PROTOCOL (ADC-039)

AM-101 in the Post-Acute Treatment of Peripheral Tinnitus 1 (AMPACT1) x an open-label extension to the TACTT2 study

AN OPEN-LABEL STUDY TO EVALUATE THE SAFETY AND PHARMACOKINETICS OF PF-06412528 IN CHILDREN 7-17 YEARS FOR THE TREATMENT OF MODERATE-TO-SEVERE CHRONIC PAIN

AN OPEN-LABEL, NON-RANDOMIZED, MULTICENTER, ASCENDING DOSE BY AGE, SINGLE- AND MULTIPLE-DOSE EVALUATION OF THE EFFECTIVENESS, SAFETY, AND TOLERABILITY OF OXYMORPHONE HCl IMMEDIATE-RELEASE ORAL LIQUID FOR ACUTE POSTOPERATIVE PAIN IN PEDIATRIC SUBJECTS

ANBL09P1, A COG Pilot Study of Intensive Induction Chemotherapy and 131I-MIBG Followed by Myeloablative Busulfan/Melphalan (Bu/Mel) for Newly Diagnosed High-Risk Neuroblastoma

ANBL1221,A Phase II Randomized Trial of Irinotecan/Temozolomide with Temsirolimus (NSC# 683864, IND# 61010) or Chimeric 14.18 Antibody (ch14.18) (NSC# 623408, IND# 4308) in Children with Refractory, Relapsed or Progressive Neuroblastoma

ANBL1232, Utilizing Response- and Biology-Based Risk Factors to Guide Therapy in Patients with Non-High-Risk Neuroblastoma

ANBL12P1,Pilot Study Using Myeloablative Busulfan/Melphalan (BuMel) Consolidation Following Induction Chemotherapy for Patients with Newly Diagnosed High-Risk Neuroblastoma

ANHL1131, Intergroup Trial for Children or Adolescents with B-cell Non-Hodgkin Lymphoma (NHL) or Mature B-cell Leukemia (B-AL): Evaluation of Rituximab Efficacy and Safety in High Risk Patients

ANHL12P1, A Randomized Phase II study of Brentuximab Vedotin (NSC# 749710) and Crizotinib (NSC# 749005) in Patients with Newly Diagnosed Anaplastic Large Cell Lymphoma (ALCL) IND #117117

AOST1322, Phase II Study of Eribulin (IND# 122686, NSC# 707389) in Recurrent or Refractory Osteosarcoma

ARQ197-A-U303 A PHASE 3, RANDOMIZED, DOUBLE-BLIND STUDY OF TIVANTINIB (ARQ 197)IN SUBJECTS WITH MET DIAGNOSTIC-HIGH INOPERABLE HEPATOCELLULAR CARCINOMA (HCC) TREATED WITH ONE PRIOR SYSTEMIC THERAPY

ARST1321, Pazopanib Neoadjuvant Trial in Non-Rhabdomyosarcoma Soft Tissue Sarcomas (PAZNTIS): A Phase II/III Randomized Trial of Preoperative Chemoradiation or Preoperative Radiation Plus or Minus Pazopanib (NSC# 737754, IND# 118613)

ASCT1221, A Randomized Phase II Study Comparing Two Different Conditioning Regimens Prior to Allogeneic Hematopoietic Cell Transplantation (HCT) for Children with Juvenile Myelomonocytic Leukemia (JMML)

ASPREE Study: Asprin in Reducing Events in the Elderly

Active Management of Preoperative Anemia to Reduce Erythrocyte Transfusion in Patients Undergoing Cardiac Surgery (APART)

Acute Stroke or Transient Ischemic Attack Treated with Aspirin or Ticagrelor and Patient Outcomes (Socrates)

Adding Liraglutide to High Dose Insulin: Breaking the Cycle

Adherence to Disease-Modifying Therapies in Pediatric Multiple Sclerosis

Adherence to Surveillance After Lung Cancer Treatment

Adhesion Markers for T-Cell Regulatory Activity in Inflammatory Bowel Disease

Adiponectins, ceramides, and depressive symptoms in obese adolescents

Adjunctive Neurovascular Support for Wide-neck aneurysm Embolization and Reconstruction (ANSWER) Study

Adjunctive Smart Phone Based Smoking Cessation Treatment

Advanced MR Imaging Techniques in the Characterization of Renal Cell Carcinoma: Correlation with Pathology and Gene Expression Profiles

Age of Blood in Children in Pediatric Intensive Care units (ABC PICU)

Amgen Protocol:20090340 An open label study evaluating the safety and efficacy of long-term dosing of Romiplostim in Thrombocytopenic pediatric subjects with immune ( Idiopathic ) Thrombocytopenia Purpura (ITP)

Amiodarone (PM101), Lidocaine or Neither for Out-Of-Hospital Cardiac Arrest Due to Ventricular Fibrillation or Tachycardia

An Analysis of Genomic and Molecular Profiles of Lung Cancer for the Prediction of Response to Therapy and Clinical Outcomes

An Evaluation of Pediatric Patients presenting to a Tertiary Care, Level 1 Trauma Pediatric Emergency Department transferred from another Emergency Center.

An International, Multicenter, Prospective Observational Study of the Safety of Maraviroc used with Optimized Background Therapy in Treatment-Experienced HIV-1 Infected Patients

An Investigation of Tumor Metabolism in Patients Undergoing Surgical Resection

An Investigation of the NMP22 Bladder Check Test for Early Detection of Bladder Cancer

An Observational Study of Hepatitis C (HCV)/ HIV Co-Infected Compared to HCV Mono-Infected Subjects

An Observational Study of Hepatitis C Virus in Pregnancy (HCV)

An Open-Label Extension Study of the Long-Term Safety of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis (IPF)

An Open-Label Study to Assess the Safety and Tolerability of ISIS 396443 in Patients with Spinal Muscular Atrophy who Previously Participated in ISIS 396443-CS2 or ISIS 396443-CS10

An Open-Label safety study for previously treated ataluren (PTC124) patients with nonsense mutation dystrphinopathy

An Open-Label, Multi-Center, 48-Week Study with a Concurrent Untreated Control Arm to Evaluate the Efficacy and Safety of Eteplirsen in Duchenne Muscular Dystrophy

An extension protocol for subjects who were previously enrolled in other Tivantinib(ARQ 197) protocols.

Analysis of Functional Recovery after West Nile Neuroinvasive Disease

Analysis of Morphogenic Effect of hDAB21P on Prostate Cancer and its Disease Correlation

Analysis of endothelial cells in rheumatoid arthritis

Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial

Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4) Study

Antibiotic Safety in Infants with Complicated Intra-Abdominal Infections(SCAMP Trial)

Antidepressant Treatment at an Inner City Asthma Clinic

Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH)-II: A Phase III Randomized Multicenter Clinical Trial of Blood Pressure Reduction for Hypertension in Acute Intracerebral Hemorrhage

Antiplatelet Strategy for Peripheral Arterial Interventions for Revascularization of Lower Extremities (ASPIRE PAD)

Approaches and Decisions for Acute Pediatric TBI

Arterial Elasticity: A Substudy of Strategic Timing of AntiRetroviral Treatment (START)

Assessing speech in patients with cleft palate using real-time MRI.

Assessment of Bleeding Severity in Children with Immune Thrombocytopenia (ITP)

Assessment of Calcium Metabolism, Parathyroid Function and Vitamin D Status in Disorders of Mineral Metabolism

Assessment of Clinical Effects of Cholesteryl Ester Transfer Protein Inhibition with Evacetrapib in Patients at a High-Risk for Vascular Outcomes - the ACCELERATE study

Assessment of added diagnostic value and impact on workflow of post-processed spectral detector CT data

Associating PARP-1-Mediated ADP-Ribose Production with Clinical Outcomes in Ovarian Cancer

Association between patient weight and successful defibrillation

Association of serum vitamin D concentration with Infection outcomes for children after surgery

Attenuation of Corticosteroid-Induced Hippocampal Changes

Aurora Kinase A as a Biomarker for the Detection of Bladder Cancer

Autonomy and participation in exercise in persons with Multiple Sclerosis

Autoreactive Treg in human Type 1 or Type 2 diabetes

BABY HUG FU II: PEDIATRIC HYDROXYUREA PHASE III CLINICAL TRIAL FOLLOW-UP OBSERVATIONAL STUDY II

BIPOLAR-SCHIZOPHRENIA NETWORK FOR INTERMEDIATE PHENOTYPES: PSYCHOSIS AND AFFECTIVE RESEARCH DOMAINS

BMS AI452032: Phase 3 open label study evaluating the efficacy and safety of pegylated interferon lambda-1a, in combination with ribavirin and daclatasvir for treatment of chronic HCV infection with treatment naive genotypes 1, 2, 3 or 4 in subjects co-infected with HIV

BOTOX treatment in pediatric upper limb spasticity: Double-blind study. Protocol: 191622-101

BOTOX(RegisteredTM) Treatment in Adult Patients with Post-Stroke Lower Limb Spasticity

BOTOX(RegisteredTM) Treatment in Pediatric Lower Limb Spasticity: Double-blind Study. Protocol: 191622-111

BOTOX(RegisteredTM) Treatment in Pediatric Upper Limb Spasticity: Open-label Study. Protocol: 191622-105

BOTOX(RegisteredTM) Treatment of Pediatric Lower Limb Spasticity: Open-label Study Protocol 191622-112

BTTC09-01: A Phase I-II trial Everolimus and Sorafenib in Patients with Recurrent High-Grade Gliomas

BTTC11-01: Randomized, double-blind, placebo-controlled trial of lacosamide for seizure prophylaxis in patients with High-Grade Gliomas

BTTC12-01: A Phase II Trial of Oral Pazopanib plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) without Prior Bevacizumab Exposure and (B) after Failing Prior Bevacizumab

Baby Observational and Nutritional Study (BONUS)

Baked Egg for Egg Allergic Children

Bang for the Buck : Assessing the impact of different features of a web-based decision aid to improve decision making for asymptomatic carotid disease

Banking of Tissue and Establishing Continuous Cell Lines and Xenografts From Neoplasia (South Plains Oncology Consortium Bank [SPOC])

Berlin Heart EXCOR Pediatric Ventricular Assist Device Post Approval Study

Bio-specimen Bank for Pediatric Tumors and Cancer Predispositions

Biomarkers for Post-Transplant Lymphoproliferative Syndrome in Children

Blood Repository for Food Allergic Patients

Brain specific cholesterol (24S-hydroxycholesterol) as a serum biomarker for hemorrhagic transformation in acute ischemic stroke

Breast Cancer Rehabilitation Improving Daily Function and Participation

Burn Multicenter Proposal: Development of an Inhalation Injury Scoring System to Predict Severity of Inhalation Injury

CAF PINT: Coagulation and Fibrinolysis in Pediatric Insulin Titration Trial Study Protocol Document

CALGB 30610/RTOG 0538: Phase III Comparison of Thoracic Radiotherapy Regimens in Patients with Limited Small Cell Lung Cancer also Receiving Cisplatin and Etoposide

CALGB C80702- A PHASE III TRIAL OF 6 VERSUS 12 TREATMENTS OF ADJUVANT FOLFOX PLUS CELECOXIB OR PLACEBO FOR PATIENTS WITH RESECTED STAGE III COLON CANCER

CCTL019A2205B: Long Term Follow-Up of Patients Exposed to Lentiviral-Based CD19 directed CART Cell Therapy

CCTL019B2202: A Phase II, single arm, multicenter trial to determine the efficacy and safety of CTL019 in pediatric patients with relapsed and refractory B-cell acute lymphoblastic leukemia

CCTL019B2206: A multicenter study of apheresis collection of peripheral blood mononuclear cells (PBMC) in patients with CD19 expressing malignancies who could be eligible for a CTL019 clinical research trial

CDC Public Health Surveillance for Bleeding Disorders - Registry for Bleeding Disorders Surveillance

CHILDREN'S MEDICAL CENTER DNA/CELL/TISSUE REPOSITORY (CMCDR)

COV02520124: An Open-Label, Safety and Pharmacokinetic Study of Hydromorphone Hydrochloride Extended-Release Tablets (Once-Daily Hydromorphone) in Opioid-Tolerant Pediatric Subjects with Chronic Pain

CRAD001CUS224T, Phase II Study of Everolimus (RAD001, AFINITOR(RegisteredTM)) for Children with Recurrent or Progressive Ependymoma

CTLA-4 Ig (Abatacept) FOR PREVENTION OF ABNORMAL GLUCOSE TOLERANCE AND DIABETES IN RELATIVES AT-RISK FOR TYPE 1 DIABETES MELLITUS: TN18

Calcium Intake and the Risk of Nephrolithiasis

Can a clinical decision rule be validated in the pediatric population to identify thoracic injuries and reduce the use of chest radiographs as a screening diagnostic test for evaluation of blunt torso trauma?

Can patient Anxiety be Alleviated with Music Therapy (The CALM Study)

Center for International Blood and Marrow Transplant Research (CIBMTR) - Consent for Participation and Donation of Blood Samples

Cerebral oxygenation and autoregulation in preterm infants: association with morbidity and mortality

Ceritinib in mutation and oncogene directed therapy in metastatic or locally advanced Anaplastic/Undifferentiated Thyroid Cancer

Characterization of Familial Idiopathic Pulmonary Fibrosis

Characterization of PDGFR-b perivascular cells from infantile hemangiomas

Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry.

Chronic Kidney Disease Antidepressant Sertraline Trial (CAST)

Chronic Kidney Disease in Children-Prospective Cohort Study (CKID)

Citicoline for Alcohol Dependence

Clinical Assessment of the Performance of a Fractional CO2 Laser System (Fraxel Repair Laser) intended for treatment of perioral rhytides/wrinkles

Clinical Development of Cancer-Specific MRS Biomarkers in Malignant Gliomas

Clinical Development of MR Spectroscopy and Imaging in Brain Cancers

Clinical Outcomes and Radiation Safety after Endovascular Repair of Complex Abdominal Aortic Aneurysms using Custom-Made Devices (CMD)

Clinical Performance of Elecsys Troponin T Gen 5 in Subjects with Symptoms of Acute Coronary Syndrome (ACS): ACS Collection Study for Serum Claim

Clinical Registry of Nephrolithiasis, Osteoporosis and Other Disorders of Mineral Metabolism

Clinical Studies on Bile Acids Barretts Esophagus

Clinical Study to Evaluate the Safety and Effectiveness of the Zenith(RegisteredTM) Branch Endovascular Graft-Iliac Bifurcation (PRSERVE)

Clinical Trial of Entecavir/Pegylated Interferon in Immunotolerant Children with Chronic HBV Infection. Hepatitis B Research Network

Clinical Trial of the On-X Valve Using Low Dose Anticoagulation

Clinical and Immunological Studies of Vitiligo

Clinical and Translational Research Center (CTRC) Case Study Protocol

Cloacal defects following obstetrical injury: presenting characteristics and subjective symptoms after sphincteroplasty

Coarctation of the Aorta Stent Trial (COAST)

Coarctation of the Aorta: Long Term Outcomes and Comorbidities

Cognitive Changes in Demylinating Diseases (A Longitudinal Study of Cognitive Assessment in patients with Multiple Sclerosis, Acute Disseminated Encephalomyelitis, Transverse Myelitis, Neuromyelitis Optica, Neurosarcoidosis and Optic Neuritis)

Cognitive and Sensorimotor Mechanisms of Autism Spectrum Disorder (ASD)

Colesevelam Oral Suspension as Monotherapy or Add-on to Metformin Therapy in Pediatric Subjects with Type 2 Diabetes Mellitus

Collaborative Assessment of Pediatric Transverse Myelitis: Understand, Reveal, Educate or CAPTURE study

Combination Therapy of Peginterferon Alfa-2a and Tenofovir versus Tenofovir Monotherapy in HBeAg-positive and HBeAg-negative Chronic Hepatitis B

Comparative Analysis of Chronobiological Changes in Burn, Trauma and Traumatic Brain Injury

Comparison Between Surgical vs Balloon Angioplasty vs Intravascular Stent Placement for Recurrent or Native Coarctation of the Aorta

Comparison of Endorectal Coil Magnetic Resonance Imaging Versus Pelvic Digital Coil Resonance Magnetic Imaging at 3 Tesla for Detection and Local Staging of Prostate Cancer

Comparison of the effect of different nephron sparing strategies on normal renal parenchyma

Compassionate Use of Omegaven in the Treatment of Parenteral Nutrition Induced Hepatic Injury

Comprehensive and Multidisciplinary Approach to Evaluation of Young Women with Heavy Menstrual Bleeding (HMB): Impact on Diagnosis, Management and Outcomes

Continuous Diffusion of Oxygen (CDO) Treatment for Healing of Diabetic Foot Ulcers

Contribution of growth factor expression to post-stroke cortical plasticity- Pilot

Controlled Randomized Double Blinded Prospective Study on the Role of Decompression of Lower Extremity Nerves for the Treatment of Patients with Symptomatic Diabetic Neuropathy With Chronic Nerve Compression

Coping with Cancer II

Corneal sensitivity and nerve fiber morphology in patients with obstructive sleep apnea.

Correction of B0 inhomogeneity Induced by Orthodontic Appliances in MRI

Correlation of changes in BMI z-score with ALT in Pediatric NAFLD

Criterion-related validity of the Wisconsin Stone-QOL: evaluating evidence for generalizability and predictive value

CureGN: Cure Glomerulonephropathy Network

Dallas Regional Autoimmune Disease Registry

Database Registry for Psychotic Disorders (DRPD)

Database of Medical Information from Healthy Volunteers

Database registry to Examine Brain Connections and Brain Function in Mental Disorders and Neural Network Biomarkers for Relational Memory and Psychosis in Schizophrenia

Defining the Tear Film Proteome

Detection of Diffuse Beta-amyloid Plaques in TBI Patients Using PET Imaging

Detection of Impaired Intrinsic Bone Strength in vivo by Ultrasound Critical Angle Reflectometry

Determining an Optimal Weaning Method of Nasal Continuous Positive Airway Pressure in Preterm Neonates

Developing a self-persuasion intervention promoting adolescent HPV vaccination

Development of a Multi-modality Non-Radiologic Image Repository and Registry

Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) (Protocol NIH N01-DK-6-2203)

Do Antenatal Steriods Affect Maturation of the Amplitude Integrated Electroencephalogram in Late Preterm Infants? A Secondary Study by the NRN for the MFMU ALPS Trial

Docosahexaenoic acid (DHA) for the treatment of pediatric concussion related to sports injury

Double-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD)

Double-Blind, Proof-of-Concept (POC) Trial of Low Field Magnetic Stimulation (LFMS) Augmentation of Antidepressant Therapy in Treatment-Resistant Depression (TRD)

E1411: Intergroup Randomized Phase II Four Arm Study In Patients With Previously Untreated Mantle Cell Lymphoma Of Therapy With: Arm A = Rituximab+ Bendamustine Followed By Rituximab Consolidation (RB [?] R); Arm B = Rituximab + Bendamustine + Bortezomib Followed By Rituximab Consolidation (RBV[?] R), Arm C = Rituximab + Bendamustine Followed By Lenalidomide + Rituximab Consolidation (RB [?] LR) or Arm D = Rituximab + Bendamustine + Bortezomib Followed By Lenalidomide + Rituximab Consolidation (RBV [?] LR)

E1412: Randomized Phase II Open Label Study of Lenalidomide R-CHOP (R2CHOP) vs RCHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisone) in Patients with Newly Diagnosed Diffuse Large B Cell Lymphoma

E1912: A Randomized Phase III Study of Ibrutinib (PCI- 32765)-based Therapy vs Standard Fludarabine, Cyclophosphamide, and Rituximab (FCR) Chemoimmunotherapy in Untreated Younger Patients with Chronic Lymphocytic Leukemia (CLL)

E2112:A Randomized Phase III Trial of Endocrine Therapy plus Entinostat/Placebo in Men and Postmenopausal Women with Hormone Receptor-Positive Advanced Breast Cancer

E2211:A Randomized Phase II Study of Temozolomide or Temozolomide and Capecitabine in Patients with Advanced Pancreatic Neuroendocrine Tumors

E2607: A Phase II Trial of Dasatinib in KIT-Positive Patients with Unresectable Locally Advanced or Stage IV Mucosal, Acral and Vulvovaginal Melanomas

E3A06: Randomized Phase III Trial of Lenalidomide Versus Observation Alone in Patients with Asympotomatic High-Risk Smoldering Multiple Myeloma

E3F05 Phase III Study of Radiation Therapy with or without Temozolomide for Symptomatic or Progressive Low-Grade Gliomas

E4512: A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-Small Cell Lung Cancer: Crizotinib versus Placebo for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion Protein

EA8141: A Prospective Phase II Trial of Neoadjuvant Systemic Chemotherapy Followed by Extirpative Surgery for Patients with High Grade Upper Tract Urothelial Carcinoma

EMR200147-500: A prospective, randomized, placebo-controlled, double-blind clinical trial to evaluate whether EGRIFTA(RegisteredTM) (tesamorelin for injection), 2 mg once daily SC, increases the risk of development or progression of diabetic retinopathy when administered to HIV-infected subjects with abdominal lipohypertrophy and concomitant diabetes

EMR200147-501: A phase 4, observational, multicenter, 10-year prospective cohort safety study comparing subjects with HIV-associated abdominal lipohypertrophy exposed to EGRIFTA (tesamorelin for injection) to a similar group of subjects not exposed to EGRIFTA

EP-ILC-201, Phase 2 Study of Inhaled Lipid Cisplatin in Pulmonary Recurrent Osteosarcoma

ERK AD-Index in the Diagnosis of Alzheimer[Single Quote]s Disease: Clinical Feasibility Protocol

EXenatide Study of Cardiovascular Event Lowering Trial (EXSCEL): A Randomized, Placebo Controlled Clinical Trial to Evaluate Cardiovascular Outcomes After Treatment with Exenatide Once Weekly in Patients with Type 2 Diabetes Mellitus

Early Psychiatric Intervention After Orthopaedic Trauma: A Prospective, Randomized Double-Blinded Placebo Controlled Trial

Effect of the NIOSH-WPV Training Course on Nurse Confidence and Attitudes towards Managing Aggressive and Violent Patients in Acute Care Settings

Effect of Passive Immunization on the Progression of Mild Alzheimer[Single Quote]s Disease: Solanezumab (LY2062430) Versus Placebo

Effect of Pharmacological Reversal of Hyperuricemia on Features of the Metabolic Syndrome

Effect of Proton Pump Inhibitor on Bioavailability of Effervescent Calcium Magnesium Citrate

Effect of lactation on ectopic lipid after gestational diabetes

Effectiveness of using electrical cauterization to treat woman found to have a specific type of bladder inflammation ( trigonitis ) with refractory lower urinary tract symptoms.

Effects of Dietary Potassium on WNK1, Blood Pressure, and Insulin Metabolism

Effects of Ghrelin on Sympathetic Nerve Activity in Humans

Effects of Nebivolol on Microvascular Perfusion in the Skeletal Muscles During Exercise in Hypertensive Patients

Effects of Pre-operative pregabalin and ketamine to prevent development of phantom pain in patients undergoing lower extremity amputation

Effects of a Community Based Exercise Program in Adults with Severe Burns

Efficacy and safety of FIAsp compared to insulin aspart both in combination with insulin detemir in adults with Type 1 diabetes. NN1218-3852

Efficacy and safety of semaglutide once-weekly versus exenatide ER 2.0 mg once-weekly as add-on to 1-2 oral antidiabetic drugs (OADs) in subjects with type 2 diabetes

Efficacy of Leptin Replacement in Treatment of Genetic and Acquired Lipodystrophies

Efficacy of Social Interaction Skills Training (SIST) Post Burn Injury: A Prospective Randomized Intervention Study

Electrical Stimulation for Improving Balance in Diabetes

Elucidation of the Role of Fat in Abnormally Acidic Urine in Patients with Nephrolithiasis

Environmental and Genetic Risk Factors for Pediatric Multiple Sclerosis

Establishing Moderators and Biosignatures of Antidepressant Response for Clinical Care (EMBARC)

Establishing a Database on the Plasma Level of Klotho in Humans, in Health and Disease

Establishment of Urologic Tissue and Serum Repository

Establishment of a biorepository at the University of Texas Southwestern for the Study of PHPV and PVR

Establishment of the Pediatric Obesity Weight Evaluation Registry (POWER): A prospective pilot project of children and adolescents presenting for weight management.

Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH)

Evaluation of Clinical Characteristics and Surgical Outcomes in Female Patients with a Urethral Diverticulum

Evaluation of Cystatin C as an Early Biomarker of Renal Dysfunction in Children with Multiple Organ Dysfunction Syndrome

Evaluation of New Self-Test Visual Function Assessment System for Diabetic Retinopathy (Phase II - DRAMA Study)

Evaluation of Pediatric Musculoskeletal Infection at Children[Single Quote]s Medical Center According to Evidence Based Guidelines: Severity of lllness Validation and Other Etiologies

Evaluation of Radiation-Induced Vasculopathy by Transcranial Doppler (TCD) Among Survivors of Childhood Medulloblastoma Treated with Cranial Radiation Therapy

Evaluation of Respiratory Acoustic Monitor in Children After Surgery

Evaluation of SEDline EEG monitoring in pediatric patients undergoing General Anesthesia or sedation

Evaluation of System Enhancements for Magnetic Resonance Imaging Hardware and Software in a Clinical Setting

Evaluation of Systemic Hypothermia Initiated After 6 Hours of Age in Infants > or equal to 36 Weeks Gestation with Hypoxic-Ischemic Encephalopathy: A Bayesian Evaluation (Late Hypothermia Study for HIE)

Evaluation of Thrombin Generation in Children with Venous Thromboembolism

Evaluation of cone-beam CT image quality

Evaluation of microRNAs as novel markers of cardiotoxicity in children undergoing anthracycline therapy for pediatric cancer

Evaluation of the UroVysion Test in Predicting Recurrence and/or Progression of Disease in Patients Receiving initial BCG for Primary High Grade Papillary Ta-T1 and CIS Urothelial Carcinoma of the Bladder

Evaluation of the biochemical and Biophysical Properties of Meibomian lipid Samples collected From Meibomian Glands of normal Donors and Dry Eye Patients

Evidence-based colorectal cancer screening for the uninsured

Exercise in Burn Survivors

Expression of co-inhibitory receptors in inflammatory disease and cancer

Extended Survival Analysis of the Dallas Newborn Cohort

FLU 006: Anti-Influenza Hyperimmune Intravenous Immunoglobulin Clinical Outcome Study

Factors affecting Emergency Department admissions in opioid-dependent patients, requiring Naloxone administration

Factors associated with adolescent HPV vaccine use in UTSW and Parkland affiliated clinics

Family Studies of Sensorimotor and Neurocognitive Heterogeneity in Autism Spectrum Disorders (ASD)

Feasibility Study using Imaging Biomarkers in Lung Cancer

Feasibility and Validity of Home-based Teleneuropsychological Screening Evaluation in Pediatric Multiple Sclerosis: An Examination of Cognitive and Academic Performance

Feasibility of CT Perfusion (CTP) as a noninvasive method for characterizing pulmonary lesions as benign or malignant: Comparison of CTP findings with histopathology and other imaging results.

Feasibility of nonmydriatic fundoscopic imaging using the PanOptic ophthalmoscope and IExaminer in the pediatric emergency room setting

Fever related illness non-urgent visit costs to a large pediatric emergency department.

Field Pilot Trial of Hypotensive Resuscitation versus Standard Resuscitation in Patients with Hemorrhagic Shock after Trauma

Finding the Causes of Rare Skin Diseases

Follow Up of and Continued Access to Covered Cheatham-Platinum Stent for Prevention or Treatment of Aortic Wall Injuries Associated with Aortic Coarctation (COAST II)

Fort Worth Program for Community Survivorship (ProComS)

Fragile X Clinical and Research Consortium Registry and Database Study

GLORIA - AF: Global Registry on Long-Term Oral Anti-thrombotic TReatment In PAtients with Atrial Fibrillation[?] (PHASE II/III)

GLORIA-AF: Global Registry on Long-term Oral Anti-thrombotic Treatment in Patients with Atrial Fibrillation

GOG 0244: The Lymphedema and Gynecologic Cancer (LEG) Study: Incidence, Risk Factors and Impact in Newly Diagnosed Patients

GOG 0275: A PHASE III RANDOMIZED TRIAL OF PULSE ACTINOMYCIN-D VERSUS MULTI-DAY METHOTREXATE FOR THE TREATMENT OF LOW-RISK GESTATIONAL TROPHOBLASTIC NEOPLASIA

GOG 0277- (IRCI 001): A Phase III Randomized Trial of Gemcitabine (NSC# 613327) plus Docetaxel (NSC# 628503) followed by Doxorubicin (NSC# 123127) v. observation for uterus-limited, High Grade Uterine Leiomyosarcoma

GOG 0278: EVALUATION OF PHYSICAL FUNCTION AND QUALITY OF LIFE (QOL) BEFORE AND AFTER NON-RADICAL SURGICAL THERAPY (EXTRA FASCIAL HYSTERECTOMY OR CONE BIOPSY WITH PELVIC LYMPHADENECTOMY) FOR STAGE IA1 (LVSI+) and IA2-IB1 (<= 2CM) CERVICAL CANCER

GOG 0279: A PHASE II TRIAL EVALUATING CISPLATIN (NSC #119875) AND GEMCITABINE (NSC #613327) CONCURRENT WITH INTENSITY-MODULATED RADIATION THERAPY (IMRT) IN THE TREATMENT OF LOCALLY ADVANCED SQUAMOUS CELL CARCINOMA OF THE VULVA

GOG 0286B: A RANDOMIZED PHASE II/III STUDY OF PACLITAXEL/CARBOPLATIN/METFORMIN (NSC#91485) VERSUS PACLITAXEL/CARBOPLATIN/PLACEBO AS INITIAL THERAPY FOR MEASURABLE STAGE III OR IVA, STAGE IVB, OR RECURRENT ENDOMETRIAL CANCER NCT #022065687

GOG 0724: Phase III Randomized Study of Concurrent Chemotherapy and Pelvic Radiation Therapy with or without Adjuvant Chemotherapy in High-Risk Patients with Early-stage Cervical Carcinoma Following Radical Hysterectomy

GOG 238: A Randomized Trial of Pelvic Irradiation with or without Concurrent Weekly Cisplatin in Patients with Pelvic-only Recurrence of Carcinoma of the Uterine Corpus

GOG 263: Randomized Phase III Clinical Trial of Adjuvant Radiation versus Chemoradiation in Intermediate Risk, Stage I/IIA Cervical Cancer Treated with Initial Radical Hysterectomy and Pelvic Lymphadenectomy

GOG 264: A Randomized Phase II Trial of Paclitaxel and Carboplatin vs. Bleomycin, Etoposide, and Cisplatin for Newly Diagnosed Advanced Stage and Recurrent Chemonaive Sex Cord-Stromal Tumors of the Ovary

GOG 265: A Phase II Evaluation of ADXS11-001 (NSC 752718, BB-IND #13,712) in the Treatment of Persistent or Recurrent Squamous or Non-Squamous Cell Carcinoma of the Cervix

GOG 274: A PHASE III TRIAL OF ADJUVANT CHEMOTHERAPY AS PRIMARY TREATMENT FOR LOCALLY ADVANCED CERVICAL CANCER COMPARED TO CHEMORADIATION ALONE: THE OUTBACK TRIAL (ANZGOG 0902/GOG-0274/RTOG 1174)

GOG 281:A RANDOMIZED PHASE II/III STUDY TO ASSESS THE EFFICACY OF TRAMETINIB (GSK 1120212) IN PATIENTS WITH RECURRENT OR PROGRESSIVE LOW-GRADE SEROUS OVARIAN CANCER OR PERITONEAL CANCER.

GOG-0076HH: A Phase I/II Trial of Paclitaxel, Cisplatin and CTEP Supplied Agent ABT-888 (IND#77840, NSC#737664) in the Treatment of Advanced, Persistent, or Recurrent Carcinoma of the Cervix

GOG-0225: CAN DIET AND PHYSICAL ACTIVITY MODULATE OVARIAN, FALLOPIAN TUBE AND PRIMARY PERITONEAL CANCER PROGRESSION-FREE SURVIVAL

GOG-0283: A PHASE II TRIAL OF DCTD-SPONSORED DASATINIB (NSC #732517 IND #120636) IN RECURRENT /PERSISTENT OVARY, FALLOPIAN TUBE, PRIMARY PERITONEAL, AND ENDOMETRIAL CLEAR CELL CARCINOMA CHARACTERIZED FOR THE RETENTION OR LOSS OF BAF250a EXPRESSION

GOG-270: GROningen INternational Study on Sentinel nodes in Vulvar cancer(GROINSS-V) II: An Observational Study

GS-US-248-0122: A Long Term Follow-up Registry for Subjects Who Achieve a Sustained Virologic Response to Treatment in Gilead-Sponsored Trials in Subjects with Chronic Hepatitis C Infection

Gemfibrozil for Nicotine Smoking Cessation

Gender Disparity and Hormones in Cystic Fibrosis

Gene Discoveries in Subjects with Crohns Disease of African Descent

Genetic Determinants of Keloid Formation Study

Genetic Determinations of Familial Chest Wall Abnormalities

Genetic Studies in Addiction

Genetic Variation in a Multi-Ethnic Population

Genetic and Biomarker Study of Alzheimer's Disease

Genetic regulators of metabolism and development in children

Group Lifestyle Balance Adapted for Impaired Mobility (GLB-AIM): Translating the GLB to Promote Healthy Weight in People with Mobility Disability (Impairment)

Guiding Evidence Based Therapy Using Biomarker Intensified Treatment (GUIDE IT)

H+-ATPase B-subunit Dysfunction and Calcium Nephrolithiasis

H-29892, Case Ascertainment for Epidemiologic Studies of Childhood Cancers and Hematological Conditions

HALF-PINT Heart and Lung Failure-Pediatric Insulin Titration Trial Study

HIV Disease Database

Health Correlates of Bullying in Pediatric Neurofibromatosis

Health Topics Survey

Hematopoietic Stem Cell Transplantation for CD40 Ligand Deficiency

Hemodialysis Fistula Maturation Consortium

Hepatocellular carcinoma Early Detection Strategy study (HEDS)

Herpes simplex virus (HSV) infection in young infants

Heterotaxy Syndrome and Intestinal Rotation Abnormalities - A Prospective Study

High Resolution Magnetic Resonance Imaging in Patients with Brain Tumors

Hippocampal Neurogenesis in Human Subjects (Pilot Study)

Hormonal Influences on the Airways

Human Analogs of RAE-1 (Retinoic Acid Early Transcript): Post-Transplant Rejection and Acute Renal Failure

Human Neonatal Brain MRI

Hydrocortisone treatment of Cardiovascular Insufficiency in Term and Late Preterm Infants: A Randomized Controlled Trial

Hypertension and Antihypertensive Therapy in Elderly Women

Hypertrophic Cardiomyopathy in Children: Age Specific Risk Stratification for Sudden Death

I-SPY 2 TRIAL (Investigation of Serial Studies to Predict Your Therapeutic Response with Imaging And moLecular Analysis 2)

ICON 1: Physician Treatment Decisions and Patient-Reported Outcomes in Pediatric Refractory Immune Thrombocytopenia

INS-3: A Phase 3, Randomized, Double-Masked, Placebo-Controlled Study of the Efficacy and Safety of myo-Inositol 5% Injection to Increase Survival without Severe Retinopathy of Prematurity (Reduce-ROP) in Extremely Premature Infants

INSPPIRE to Study Acute Recurrent and Chronic Pancreatitis in Children

IV Ibuprofen for the Prevention of Post-ERCP Pancreatitis: A Pilot Study

Icariin to Prevent Corticosteroid-related Memory Changes

Identification of Genomic Predictors of Adverse Events after Cardiac Surgery

Immunologic and Genetic Profiles in Subsets of Morphea Patients

Impact of Body weight on the pharmacokinetic analysis of Doxorubicin and Cyclophosphamide in Breast Cancer Patients

Impact of the AHRQ TeamSTEPPS Curriculum on Biometric Stress-Markers, Team Performance and ACLS Algorithm Adherence

Implantation of the HiRes90K(TM) Advantage Cochlear Implant with HiFocus(TM) Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults with Partial Deafness

Implementation of an Electronic Medical Record Guided Intra-Operative Anesthesia Handoff Process: An Outcome Based Study

Improving CKD Detection and Care in a High-Risk, Underserved Population

Improving Emergency Department DischargeThrough Physician Directed Instructions and A Simple Algorithm Designed for Residents in Training: The R2D2 Disposition Protocol

Improving Pain Management and Long Term Outcomes Following High Energy Orthopedic Trauma (PAIN Study)

Incidence and outcome of rhinovirus in children undergoing hematopoietic stem cell transplantation

Incidence of local PIN site inflammation following Gamma Knife procedure (IPin study)

Incubator Weaning of Moderately Preterm infants: A Randomized Controlled Trial

Induction in Nulliparous Women at 39 Weeks to Prevent Adverse Outcomes: A Randomized Controlled Trial

Instant Total Contact Cast (ITCC) To Heal Diabetic Foot Ulcers: An Investigator Blinded Randomized, Controlled Clinical Trial with Three Parallel Treatment Groups

Integrating Evidence Based Pediatric Pre-Hospital Protocols into Practice

Interagency Registry of Mechanically Assisted Circulatory Support

International Pediatric Peritoneal Dialysis Network (IPPN)

International Pediatric Stroke Study-2

Interstitial Radioactive Iodine Implants for the Treatment of Pan-invasive Pituitary Macroadenomas

Investigating the Feasibility of Using Rapid Cine-MRI for Monitoring Moving and Deforming Tumors

Investigational Plan for the Clinical Study of the ARTISAN(RegisteredTM) Aphakia Lens for the Correction of Aphakia in Children

JCV Antibody Program in Patients with Relapsing Multiple Sclerosis Receiving or Considering Treatment with Tysabri: STRATIFY-2

JoLT-Ca A Randomized Phase III Study of Sublobar Resection (SR) versus Stereotactic Ablative Radiotherapy (SAbR) in High Risk Patients with Stage I Non-Small Cell Lung Cancer (NSCLC), The STABLE-MATES Trial

Keeping moms toasty: Are we doing enough? Retrospective analysis of the prevalence of maternal hypothermia following an elective cesarean delivery and its potential causes

Kidney Cancer New Pathway Discovery Project

LDL and Cholesterol Metabolism

LIDO (Lidocaine Infusion as a Treatment for Cocaine Relapse and Craving)

LONG TERM INVESTIGATIVE FOLLOW-UP IN TRIALNET (LIFT)(Protocol TN-16)

LTS13769: An open-label, multicenter, multinational extension study of the long-term safety and pharmacokinetics of repeated biweekly infusions of neoGAA in patients with Pompe disease

Lenticulostriate Vasculopathy in Preterm Infants: Characteristics, Associated Conditions, Inter-rater Reliability of Cranial Ultrasound Readings and Long-term follow-up

Leucine in DBA: The Use of Novel Therapies to Reconstitute Blood Cell Production and Promote Organ Performance, using Bone Marrow Failure as a Model: A Pilot, Phase I/II Study of the Amino Acid Leucine in the Treatment of Patients with Transfusion-Dependent Diamond Blackfan Anemia

Leveraging Technology To Provide The Next Generation of Clinical Connectivity

Lidocaine Infusion for Chronic Pain in Opioid Dependent Patients

Liraglutide Effect and Action in Diabetes: Evaluation of cardiovascular outcome Results

Liver Diseases Database

Local Antibiotic Therapy to Reduce Infection after Operative Treatment of Fractures at High Risk of Infection: A Multicenter Randomized, Controlled Trial (VANCO) [FDA IND #119891]

Long-term effectiveness of Sacrospinous Ligament Fixation (SSLF) versus Uterosacral ligament Suspension (ULS) with and without perioperative Behavioral Therapy/ Pelvic muscle Training: The Extended operations and pelvic muscle training in the management of apical support loss ( E-OPTIMAL) study

Low Carbohydrate Diet: The Effects on Non Alcoholic Fatty Liver Disease in Obese Teens

Low-Dose UVA1 Radiation in Cutaneous Lupus Patients

Low-dose propofol infusion as an abortive treatment for migraine headaches in pediatric patients

Lung Cancer Mutation Consortium Protocol

Lurasidone Effects on Tissue Glutamate in Schizophrenia

M12-667 Extension Study to Evaluate the Long-Term Safety and Efficacy of Elagolix in Subjects with Moderate to Severe Endometriosis-Associated Pain

M9177: Phase II Study of Dose-Adjusted EPOCH+/- Rituximab in Adults with Untreated Burkitt Lymphoma, C-Myc Positive Diffuse Large B-Cell Lymphoma and Plasmablastic Lymphoma

MECHANISMS OF MUSCLE ATROPHY IN SEVERE BURN AND INJURY

MISTIE III: A phase III, randomized, open-label, 500-subject clinical trial of minimally invasive surgery plus rt-PA in the treatment of intracerebral hemorrhage.

MK5172-052: A Phase II/III Randomized Clinical Trial to Study the Efficacy and Safety of the Combination Regimen of MK-5172 and MK-8742 in Subjects with Chronic Hepatitis C Virus Infection and Chronic Kidney Disease

MRI Examination Performance Efficiency Improvement

Maintenance Chemotherapy Versus Consolidative Stereotactic Body Radiation Therapy (SBRT) plus Maintenance Chemotherapy for Stage IV Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II Trial

Major Extremity Trauma Research Consortium (METRC)

Management and Outcome of Patients with Hysterectomy and Myomectomy

Markers predicting adverse pregnancy outcomes

Mechanism of Increased Ambulatory Blood Pressure in Patients With Intradialytic Hypertension and Hemodialysis Controls: A Case Control Study and Crossover Trial Comparing Carvedilol and Prazosin Hydrochloride

Micro-RNA Expression Profiling of Patients with Primary Immunodeficiency Diseases.

Mild Cognitive Impairment: Cerebrovascular Dysfunction and Exercise Training

Mild and Moderate TBI Biomarker Study

Minimally Invasive Prostatic Vapor Ablation - Multicenter, Randomized, Controlled Study for the Treatment of BPH (Rezum II)

Mitigating the Gastrointestinal Side Effects of Dimethyl Fumarate (DMF) through a Novel Intervention

Molecular Basis of Autosomal Dominant Hypercholesterolemia and Other Severe Dyslipidemias in a Multiethnic Cohort

Molecular Basis of Cholesterol Metabolism and Selected Other Genetic Disorders

Molecular Characteristics of Tumor Cells

Molecular Genetic Changes of Ovarian Cancer

Molecular Studies of Cutaneous Lupus

Molecular mechanisms of renal phosphate transport in human health and disease

Molecularly Targeted Therapy for Soft Tissue Sarcoma in Texas - Biospecimen Banking Protocol

Montreal Cognitive Assessment for Detection of MCI in African Americans

Multi Center Prospective Analysis of Treatment Outcome in Patients with Large Acoustic Neuromas Receiving Subtotal Resection with Backup Stereotactic Radiation Therapy (A.N.S.R.S)

Multi-center, randomized controlled study of the NeuRx(RegisteredTM) Diaphragm Pacing System[?] in participants with Amyotrophic Lateral Sclerosis (ALS)

Multi-modality study of brain function using near-infrared spectroscopy and transcranial direct current stimulation (tDCS).

Multi-site, prospective, open-label, long-term, flexible dose, interventional study to evaluate the safety and tolerability of clobazam as adjunctive therapy in paediatric patients aged >=1 to <=16 years with Dravet Syndrome 14362B

Multi-site, prospective, randomised, double-blind, placebo-controlled, parallel-group, interventional study to evaluate the efficacy, safety, and tolerability of clobazam as adjunctive therapy in paediatric patients aged >=1 to <=16 years with Dravet Syndrome 14362A

Multicenter ALS Cohort Study of Oxidative Stress and Disease Progression

Multicenter PLS Cohort Study of Oxidative Stress and Disease Progression

Muscle Invasive Bladder Cancer Quality of Care Initiative: A Two Phased Improvement Protocol

Muscular Dystrophy Association (MDA) U.S. Neuromuscular Disease Registry

Mutational Spectrum of Anterior Segment ophthalmic disorders

N1174: Phase I/Comparative Randomized Phase II Trial of TRC105 plus Bevacizumab versus Bevacizumab in Bevacizumab-Naive Patients with Recurrent Glioblastoma Multiforme

NMTRC V0706, A Phase II Trial of Nifurtimox for Refractory or Relapsed Neuroblastoma or Medulloblastoma

NN2211-3659 Efficacy and safety of liraglutide in combination with metformin versus metformin monotherapy on glycemic control in children and adolescents with type 2 diabetes [?] A 26-week double-blind, randomised, parallel group, placebo controlled multi-centre trial followed by a 26-week open-label extension

NN7999-3774 Safety, Efficacy and Pharmacokinetics of N9-GP in Previously Treated Children with Hemophilia B

NON-INVASIVE HEMOGLOBIN (SPHB) MEASUREMENT VIA PULSE CO-OXIMETRY ON PEDIATRIC SUBJECTS

NRG BN001 Randomized Phase II Trial of Hypofractionated Dose-Escalated Photon IMRT or Proton Beam Therapy Versus Conventional Photon Irradiation With Concomitant and Adjuvant Temozolomide in Patients With Newly Diagnosed Glioblastoma

NRG-HN001: RANDOMIZED PHASE II AND PHASE III STUDIES OF INDIVIDUALIZED TREATMENT FOR NASOPHARYNGEAL CARCINOMA BASED ON BIOMARKER EPSTEIN BARR VIRUS (EBV) DEOXYRIBONUCLEIC ACID (DNA)

NSABP B-51: A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chest Wall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative Axillary Nodes After Neoadjuvant Chemotherapy

National Collaborative to Improve Care of Children with Complex Congenital Heart Disease: A project of the Joint Council of Congenital Heart Disease (JCCHD)

Natural History Study of the Development of Type 1 Diabetes (Protocol TN-01)

Near-Infrared Spectroscopy for Pediatric Acute Scrotum and Testicular Torsion

Nebulized magnesium sulfate versus normal saline as a vehicle for albuterol in children with moderate to severe asthma exacerbation: a randomized controlled trial.

Negative Pressure Wound Therapy as a Drug Delivery System

Negative Pressure Wound Therapy in High Risk Patients Undergoing Cesarean Section

Nephrolithiasis in Patients with Primary Hyperparathyroidism

Nephrotic Syndrome Study Network

Neural Correlates of Effort Computation in Schizophrenia

Neural Mechanisms of Multiple Sclerosis Related Cognitive Change

Neural Mechanisms of Tyrosine Kinase Inhibitor-Induced Hypertension in Humans

Neural mechanisms of aldosterone-induced insulin resistance.

Neurobiology of Alzheimer's Disease and Aging - (Genetics of Dementing Brain Diseases)

Neurodevelopmental Effects of Donor Human Milk vs. Preterm Formula in ELBW Infants

Neuroimaging and Neurodevelopmental Outcome: A Secondary to Surfactant Positive Airway Pressure and Pulse Oximetry Trial (Support-IRB File #012005-019)

Neuroimaging to predict coma emergence and recovery: A pilot study (NICER pilot)

Neutrophil Function in Cystic Fibrosis Patients

Non-Invasive Evaluation of Brain Oxygen Metabolism Using Magnetic Resonance Imaging

Non-invasive Visualization by Diagnostic Ultrasonography of the Radial Artery in Vivo of Normal Subjects and Subjects with Chronic Kidney Disease

Nonmyeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Thalassemia

North Texas Burn Rehabilitation Model System

North Texas Traumatic Brain Injury Model System: Clinical Data and Demographic Information of Patients with Traumatic Brain Injury [Protocol Number H133A020526]

Novel Prediction Models for Patient-Centered Clinical Outcomes after Transcatheter Aortic Valve Replacement for Aortic Stenosis

Novel Therapies in Moderately Severe Alcoholic Hepatitis

Novel Therapies in Severe Alcoholic Hepatitis

Novel Treatment of Emotional Dysfunction in PTSD

OVA1(RegisteredTM) Post Marketing Surveillance Study PS110001

Observational Study of Children Acute Liver Failure in North America (Cohort Study)

Observational Study of Children with Hepatitis B Virus Infection in North America: A Cohort study protocol of the Hepatitis B Research Network (HBRN)

Observational Study of Hepatitis B Virus (HBV) in Patients Coinfected with Human Immunodeficiency Virus (HIV)

Observational Study of Persons with Hepatitis B Virus Infection in North America (Cohort Study)

Occult Gastrointestinal Bleeding caused by Portal Hypertensive Gastropathy in patients with Chronic Liver Disease

Odyssey Outcomes:A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Effect of Alirocumab (SAR236553/REGN727) on the Occurrence of Cardiovascular Events in Patients Who Have Recently Experienced an Acute Coronary Syndrome

Once-Weekly intravenous liposomal amphotericin B (AmBisome) for fungal prophylaxis in pediatric high-risk hematologic malignancy: A retrospective evaluation of safety and tolerability

Ondansetron for Bipolar Disorder and Alcohol Use Disorders

Open-Label Follow-Up Study of the VIPES Study to Evaluate Long-Term Efficacy and Safety of the VIASKIN Peanut

Optimization and Validation of Magnetic Resonance Imaging of Brown Adipose Tissue in Humans

Optimizing Cooling Strategies at <6 hours of Age for Neonatal Hypoxic-Ischemic Encephalopathy(HIE)

Oral Insulin for Prevention of Diabetes in Relatives At Risk For Type 1 Diabetes Mellitus (Type 1 Diabetes TrialNet Protocol TN-07)

Osteomyelitis: Procalcitonin to diagnose and monitor osteomyelitis.

Outcomes AlloMap Registry (OAR) study and sub study: Utility of Donor-Derived Cell-free DNA in Association with Gene-Expression Profiling (AlloMap) in Heart Transplant Recipients (D-OAR)

Outcomes of Children with Blunt Abdominal Trauma Transferred to a Pediatric Trauma Center After Blunt Abdominal Injury

PEANUT SUBLINGUAL IMMUNOTHERAPY INDUCTION OF CLINICAL TOLERANCE IN NEWLY DIAGNOSED PEANUT ALLERGIC 12 TO 48 MONTH OLD CHILDREN

PERL: A multicenter clinical trial of allopurinol to prevent GFR loss in type 1 Diabetes

PET Avidity in Cachexia-Inducing Lung and Gastrointestinal Tumors

PFAST: Pediatric Foramen Ovale and Stroke in Sickle Cell Disease

PHASE 3B/4 RANDOMIZED SAFETY ENDPOINT STUDY OF 2 DOSES OF TOFACITINIB IN COMPARISON TO A TUMOR NECROSIS FACTOR (TNF) INHIBITOR IN SUBJECTS WITH RHEUMATOID ARTHRITIS

PIDTC 6902, A Retrospective and Cross-Sectional Analysis of Patients Treated for SCID Since January 1, 1968

PIDTC Protocol # 6903, Analysis of Patients Treated for Chronic Granulomatous Disease Since January 1, 1995

PIDTC Protocol # 6904, Analysis of Patients Treated for Wiskott-Aldrich Syndrome Since January 1, 1990

PPHM 1202: SUNRISE: A Phase III, Randomized, Double-Blind, Placebo-Controlled Multicenter Trial of Bavituximab Plus Docetaxel versus Docetaxel Alone in Patients with Previously Treated Stage IIIb/IV Non-Squamous Non-Small-Cell Lung Cancer

PROSPR Project 1: Identifying and tracking personalized CRC screening regimens for patients in clinical settings

PROSPR Project 3: Organizational & patient factors influencing guideline-based CRC screening

Parkinsons Disease biomarkers program

Parkland Memorial Hospital Tbit(TM) Evaluation

Parkland-UT Southwestern PROSPR Center: Cervical Cancer screening in a safety net

Parkland-UT Southwestern PROSPR Center: Colon cancer screening in a safety net

Paroxysmal Nocturnal Hemoglobinuria (PNH) Registry

Participation in Registry, Research Database, and Research Sample Repository for Patients Undergoing Hematopoietic Cell Transplantation or Cellular Therapies

Pathophysiology of Uric Acid Nephrolithiasis

Patient-centered Research into Outcomes Stroke patients Prefer and Effectiveness Research (PROSPER)

Pediatric Cataract Surgery Outcomes Registry

Pediatric Multiple Sclerosis and other Demyelinating Diseases Database

Peri-operative Assessment of the Hypothalamic-Pituitary-Adrenal Axis Predicts Outcome in Neonates Undergoing Cardiac Surgery

Permanent gastric electrical stimulation in children and adolescents

Personalized Genetic History and Triple Negative Breast Cancer

Pharmacokinetics of amlodipine besylate at delivery and during lactation

Pharmacologic MRI in Cocaine-addiction

Pharmacological Therapy for Calcium Phosphate Urolithiasis

Phase 0 pharmacodynamic study of the effects of itraconazole on tumor angiogenesis and the Hedgehog pathway in early-stage non-small cell lung cancer

Phase 1B study of PD-0332991 in combination with T-DM1 in the treatment of patients with advanced HER2-positive breast cancer

Phase 2 Historically Controlled Trial of Corticosteroids in Young Boys with DMD

Phase 2 Study of Rasagiline for Treatment of Amyotrophic Lateral Sclerosis

Phase 3, Randomized, Placebo-Controlled, Double-blind, Multi-Center, Two-Part Study of Patritumab (U3-1287) in Combination with Erlotinib in EGFR Wild-type Subjects with Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) Who Have Progressed on at Least One Prior Systemic Therapy

Phase I Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of Topical GSK 1278863 in Healthy Volunteers and Diabetic Patients, and Repeat Doses of GSK 1278863 in Diabetic Patients for the Treatment of Diabetic Foot Ulcers

Phase I/II Trial of Fenretinide/LXS oral powder (NSC 374551) plus Ketoconazole in Recurrent Ovarian Cancer, Fallopian Tubes and Primary Peritoneal Carcinoma

Phase II Randomized, Double Blind, Placebo Controlled, Safety and Pharmacokinetic Study of a Single Dose of Inositol in Premature Infants

Phase II Study of Stereotactic Ablative Radiotherapy (SABR) for Low/Intermediate Risk Prostate Cancer with Injectable Rectal Spacer

Phase II Trial of Hippocampal-Avoiding Whole Brain Irradiation with Simultaneous Integrated Boost for Treatment of Brain Metastases

Phase II Trial of Molecularly Determined Treatment of Children and Young Adults with Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

Phase II Trial of Sipuleucel-T and Stereotactic Ablative Body Radiation (SABR) for Patients with metastatic castrate-resistant Prostate Cancer (mCRPC)

Phase II multicenter randomized, double blind, placebo controlled study assessing the efficacy of buparlisib (BKM120) plus paclitaxel vs. placebo plus paclitaxel in patients with platinum pre-treated recurrent or metastatic head and neck squamous cell carcinoma

Phase II study of VS-6063, a Focal Adhesion Kinase (FAK) inhibitor, in patients with KRAS mutant non-small cell lung cancer

Phase II trial of carboplatin/paclitaxel and cetuximab, followed by carboplatin/paclitaxel/cetuximab and erlotinib, with correlative studies in patients with metastatic or recurrent squamous cell carcinoma of the head and neck.

Phase III Intergroup Study of Temozolomide Alone versus Radiotherapy with Concomitant and Adjuvant Temozolomide versus Radiotherapy with Adjuvant PCV Chemotherapy in Patients with 1p/19q Co-deleted Anaplastic Glioma

Phase III Trial on Concurrent and Adjuvant Temozolomide Chemotherapy in Non-1P/19Q Deleted Anaplastic Glioma: The Catnon Intergroup Trial

Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Ularitide (Urodilantin) Intravenous Infusion in Patients Suffering from Acute Decompensated Heart Failure [TRUE-AHF]

Philips Pivotal Clinical Trial for MRI-guided High Intensity Focused Ultrasound Ablation of Uterine Fibroids

Physiological, Neural and Cognitive Bases of Age-Related Working Memory Change

Pilot Observational Study to Determine Feasibility of a Standardized Treatment of Pulmonary Exacerbations in Patients with Cystic Fibrosis (STOP)

Pilot Study of NeuroTriage Device in Patients with Potential Brain Injury and/or Impairment

Pilot Study of patient acceptance in allowing surgeon training of new technologies

Pilot study to determine prevalence of nonadherence to antihypertensive medications in the primary care clinics

Pilot study to investigate potential clinical applications of newly identified general tumor markers

Pilot study: Intensive education in a residential camp setting for families of young children with Type 1 diabetes

Plasma ceramides and correlation with adiponectin levels in children and adolescents with type 2 diabetes.

Platelet-Oriented Inhibition in New TIA and minor ischemic stroke (POINT) Trial

Post Approval Study of the AcrySof IQ Toric High Cylinder Power Intraocular Lens (IOL)

Post Operative Neurogenic Pain and Peripheral Nerve Surgical Treatment Options

Potential Role of Gastrointestinal Alkali Loss in Patients with Uric Acid Nephrolithiasis

Potential Role of Gastrointestinal Microflora in Increased Acid Production in Patients with Uric Acid Nephrolithiasis

PrECOG 0102-Randomized, Double-Blind, Placebo-Controlled Phase II Trial of Fulvestrant (Faslodex) plus Everolimus in Post-Menopausal Patients with Hormone-Receptor Positive Metastatic Breast Cancer Resistant to Aromatase Inhibitor Therapy

Predicting Response to Standardized Pediatric Colitis Therapy: The PROTECT Study

Predicting Treatment Response for Cervical Cancer: Assessment Using BOLD MRI

Predictors and impact of MyChart use among patients treated at an NCI-designated cancer center

Pregnancy Effects on Airway Disease

Pregnancy Outcomes of Women with Pulmonary Hypertension

Prehospital Air Medical Plasma (PAMPer) Phase III Multicenter, Prospective, Randomized, Open-label, Interventional Trial

Prehospital Tranexamic Acid Use for Traumatic Brain Injury

Preventing Perinatal Depression (PRE-D): Developing Tools and Interventions

Procurement of Patient Tissue Samples to Facilitate the Study of Disorders of Mineral Metabolism

Procurement of Patient and Control Blood Samples for Deposit in a Cell/DNA Repository to Facilitate the Study of Disorders of Mineral Metabolism

Prolonging Remission in Depressed Elderly (PRIDE).

Prospective Evaluation of Patients with Hip Pathology Undergoing Treatment

Prospective Evaluation of Ruxolitinib Efficacy for CNL/aCML Patients with Mutation of CSF3R

Prospective MRI evaluation of liver function and recovery in pregnancies complicated by HELLP syndrome

Prospective Registry of Pediatric/Adolescent/Young Adult Patients Treated for Upper and/or Lower Extremity Deformity and/or Limb Length Discrepancy

Prospective Research in Infants with Mild Encephalopathy

Prospective and Retrospective Outcomes in Nasal, Functional, Cosmetic, and Reconstructive Surgery

Prospective, Multi-Center Adolescent Clavicle Shaft Fracture Registry

Prospective, multicentre, international Registry of male and female patients newly diagnosed with atrial fibrillation. GARFIELD

Protocol HVTN 505: Phase 2b, randomized, placebo-controlled test-of-concept trial to evaluate the safety and efficacy of a multiclade HIV-1 DNA plasmid vaccine followed by a multiclade HIV-1 recombinant adenoviral vector vaccine in HIV-uninfected, adenovirus type 5 neutralizing antibody negative, circumcised men and male-to-female (MTF) transgender persons, who have sex with men

Protocol for Creation of Primary Liver Cancer Cell/Tissue/DNA Repositories

Protocol for Long Term Study of Brain Injury in Children - Blood, Serum, CSF and DNA Repository and Database

Psychiatry Clinical Research Infrastructure (P-CRI) Healthy Controls Database

Psychoeducation for HCV and Alcohol Behaviors

Psychological Prospective Monitoring of Children and Adolescents Referred for Gender Dysphoria to a Multidisciplinary Care Center

Quality of Life Assessment in the Pediatric Cardiac Population: Testing the Pediatric Cardiac Quality of Life Inventory

Quality of Life after Risk-Reducing Removal of Ovaries

RANDOMIZED, MULTICENTER, PHASE III, OPEN-LABEL STUDY OF ALECTINIB VERSUS CRIZOTINIB IN TREATMENT-NA[?]VE ANAPLASTIC LYMPHOMA KINASE[?]POSITIVE ADVANCED NON[?]SMALL CELL LUNG CANCER

RCT of strategies to improve screening rates among a cohort of cirrhotic patients at high risk for developing HCC, in a safety-net health system.

RTOG 0813: Seamless Phase I/II Study of Stereotactic Lung Radiotherapy (SBRT) for Early Stage, Centrally Located Non-Small Cell Lung Cancer (NSCLC) in Medically Inoperable Patients

RTOG 0912: A RANDOMIZED PHASE II STUDY OF CONCURRENT INTENSITY MODULATED RADIATION THERAPY (IMRT), PACLITAXEL AND PAZOPANIB (NSC 737754)/PLACEBO, FOR THE TREATMENT OF ANAPLASTIC THYROID CANCER

RTOG 1306 A RANDOMIZED PHASE II STUDY OF INDIVIDUALIZED COMBINED MODALITY THERAPY FOR STAGE III NON-SMALL CELL LUNG CANCER (NSCLC)

RTOG 631 Phase II/III study of image-guided radiosurgery/SBRT for localized spine metastasis

RTOG 815 PHASE III PROSPECTIVE RANDOMIZED TRIAL OF DOSE-ESCALATED RADIOTHERAPY WITH OR WITHOUT SHORT-TERM ANDROGEN DEPRIVATION THERAPY FOR PATIENTS WITH INTERMEDIATE-RISK PROSTATE CANCER

RTOG 920 A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally-Advanced Resected Head and Neck Cancer

RTOG 924 ANDROGEN DEPRIVATION THERAPY AND HIGH DOSE RADIOTHERAPY WITH OR WITHOUT WHOLE-PELVIC RADIOTHERAPY IN UNFAVORABLE INTERMEDIATE OR FAVORABLE HIGH RISK PROSTATE CANCER: A PHASE III RANDOMIZED TRIAL

Racial Influences on Medical Therapy in Glaucoma

Raise your hand if you[Single Quote]re not here: How do glaucoma patients perceive their vision loss?

Randomized Trial of Adjuvant Curcumin after Radical Prostatectomy

Randomized Trial of the Safety and Effectiveness of 3% vs. 23% Hypertonic Saline for the Treatment of Pediatric Intracranial Hypertension: A Pilot Study

Randomized double blind placebo Controlled parallel- group study to assess cardiovascular outcomes following treatment with ertugliflozin in subjects with type 2 diabetes mellitus and established vascular disease.

Randomized trial of laparoscopic versus abdominal hysterectomy for benign indications and impact on surgical success

Randomized, Double Blind, Placebo-Controlled Trial of the Safety and Efficacy of HORIZANT(RegisteredTM) (Gabapentin Enacarbil) Extended-Release Tablets for the Treatment of Alcohol Use Disorder

Randomized, Double-Blind, Multicenter, Phase 3 Study Comparing Veliparib Plus Carboplatin and Paclitaxel Versus Placebo Plus Carboplatin and Paclitaxel in Previously Untreated Advanced or Metastatic Squamous Non-Small Cell Lung Cancer (NSCLC)

Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Multicenter Study To Assess The Efficacy And Safety Of Rifaximin Soluble Solid Dispersion (SSD) Tablets For The Prevention Of Complications In Subjects With Early Decompensated Liver Cirrhosis

Randomized, Double-Blind, Vehicle-Controlled Pilot Study of the Efficacy and Safety of HylaCareTM in the Treatment of Acute Skin Changes in Patients Undergoing External Beam Radiotherapy for Tumors of the Breast.

Rate of return of patients discharged from a large pediatric emergency room with abnormal discharge vital signs.

Reduction of Cardiac Steatosis and Improvement of Diastolic Function by Modulating Metabolic Health in Obese Individuals

Regional Manual Therapy and Motor Control Exercise for the Management of Chronic Low Back Pain with Hip and Spine Motion Loss: A Randomized Clinical Trial

Registry Study to Evaluate the Clinical Outcomes of Cancer Patients and Benign Diseases Treated With Radiation at the University of Texas Southwestern Medical Center

Registry and Biorepository for the study of Inflammatory Bowel Disease

Registry for Asthma Characterization and Recruitment 2

Regulation of Renal Calcium Transport by Acid-Base and Magnesium

Rehabilitation of liver transplant patients: A preliminary study on post-liver transplant patients at UT Southwestern Medical Center

Representation of Facial Identity and View-point in the Ventral Temporal Cortex

Research to Evaluate an Effective Community-level Intervention for Young Black Men Who Have Sex with Men

Resection of skull base tumors involving facial nerve: Results after immediate nerve grafting

Retrospective Analysis of the Use of Remifentanil for Cesarean Delivery under General Anesthesia.

Retrospective Chart Review Case Study Renal Transplantation in the Presence of HLA-DQ and DP Antibodies: An Option for Highly Sensitized Patients

Retrospective Chart Review of Lung Cancer Patients from 2000 to 2008

Retrospective Chart Review of Renal Cell Carcinoma patients treated from 1/1/2000 to 10/1/2013

Retrospective Review of Failure Rate of Fixation and Resubluxation of Lisfranc Fracture Dislocation Treated with Open Reduction Internal Screw Fixation

Retrospective Review of Palliative Care Patients with Cachexia: 2002-2013

Retrospective imaging evaluation of obstructive and restrictive diffuse lung diseases.

Retrospective/Prospective analysis of PET and PET-CT studies for the diagnosis of brain, head & neck, thoracic, abdominal and pelvic diseases

Reversing Corticosteroid-Induced Memory Impairment. November, 2009

Risk Factor Analysis of Hereditary Breast and Ovarian Cancer

Risk Factors Underlying Increased Susceptibility and Severity of Lupus Nephritis

Risk Stratification and Identification of Immunogenetic and Microbial Markers of Rapid Disease Progression in Children with Crohn's Disease

Rituximab Plus Cyclophosphamide Followed by Belimumab for the Treatment of Lupus Nephritis

Role of Intestinal Microbiota in Children with Intestinal Failure and Bacterial Overgrowth

S1400 - Phase II/III Biomarker-Driven Master Protocol for Second Line Therapy of Squamous Cell Lung Cancer

SBRT Spine: Phase II Study of Stereotactic Body Radiation Therapy and Vertebroplasty for Localized Spinal Metastasis

SPOC-2012-001, Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors

SPOC-2013-001, Phase I Study of Fenretinide (4-HPR, NSC 374551) Lym-X-Sorb(LXS) Oral Powder Plus Ketoconazole Plus Vincristine in Patients with Recurrent or Resistant Neuroblastoma (IND #: 68,254)

SPOC-2014-001, Expanded Access Study of Fenretinide (4-HPR, NSC 374551) Lym-X-Sorb(LXS) Oral Powder Plus Ketoconazole in Patients with Recurrent or Resistant Neuroblastoma (IND #68,254)

SPRITES (Sertraline Pediatric Registry For the Evaluation of Safety): A Non-Interventional, Longitudinal, Cohort Study to Evaluate the Effects of Long-term Sertraline Treatment in Children and Adolescents

SQUELCH-C: Study of Quadruple Therapy with Eltrombopag for Chronic Hepatitis C

Safety Lead-in Phase II Trial of Neo-adjuvant SABR for IVC Tumor Thrombus in Newly Diagnosed RCC

Safety of Ultrasound-guided supraclavicular block: A retrospective analysis of consecutive case over a 4- year period in a teaching institution

Sentinel Lymph Node Working Group Data Acquisition Project

Shortness of Breath During Exertion in Obesity

Sildenafil for Treatment of Microvascular Compromise in Alzheimer's Disease

Silent Infarct Transfusion Trial (SITT)

Simultaneous Bilateral vs Unilateral Total Knee Arthroplasty, a Review of Safety and Efficacy at a Single Institution

Situational Factors Associated with Caregiver Burnout in Emergency Department Nurses (FACE)

Something New Under the Sun: A Randomized, Double-Blinded, Controlled Trial of UVA1 Phototherapy in Morphea

Sphingosine-1-phosphate signaling in IBD

Spinal Muscular Atrophy (SMA) Biomarkers in the Immediate Postnatal Period of Development

Standard Consent for Psychiatric Screening

Standardizing creatinine clearance estimation for the Calvert formula to improve the safety and efficacy of carboplatin

Stem Cell Studies in Peritoneal Dialysis

Strategic Timing of AntiRetroviral Treatment (START)

Strategies Using Darbepoetin alfa to Avoid Transfusions in Chronic Kidney Disease

Stroke Hyperglycemia Insulin Network Effort (SHINE) Trial

Studies of Pediatric Liver Transplantation (SPLIT)

Studies of daily anatomic change and tumor position for adaptive radiation therapy

Study of Genetic Predisposition of type 2 diabetes mellitus among South Asians

SureScan Pacing System Post-Approval Study (SureScan PAS)

Survey of Morbidity and Mortality Among High Risk Preterm Infants (GDB)

Survival Outcomes after Debulking Surgery in Gynecologic Patients with Decreased Preoperative Core Muscle Size

Sustain-5- Add on Basal Insulin: Efficacy and safety of semaglutide once- weekly versus placebo as add-on to basal insulin alone or basal insulin in combination with metformin in subjects with type 2 diabetes

Sustained Treatment of Paroxysmal Atrial Fibrillation Post-Approval Study (STOP AF PAS)

Systolic Blood Pressure Intervention Trial(SPRINT)

T2008-002, A Phase I Trial of NECTAR (Nelarabine, Etoposide and Cyclophosphamide in T-ALL Relapse): A Joint Study of TACL, POETIC and ITCC

T2009-003, A Pilot Study of Decitabine and Vorinostat with Chemotherapy for Relapsed ALL

T2014-004, A retrospective cohort study of re-induction treatment outcome among pediatric patients with relapsed or refractory B-cell precursor acute lymphoblastic leukemia (ALL)

TDCS Enhanced Stroke Recovery and Cortical Reorganization

TIGER 1: A Randomized, Open-Label, Phase II Study of CO-1686 or Erlotinib as First-Line Treatment of Patients with EGFR-Mutant Advanced Non-Small Cell Lung Cancer (NSCLC)

TRANSCRANIAL DIRECT CURRENT STIMULATION FOR THE TREATMENT OF POSITIVE AND COGNITIVE SYMPTOMS IN SCHIZOPHRENIA

TRICS-III: Transfusion Requirements in Cardiac Surgery

Technology Development for Intracellular Metabolites at 7 Tesla

Technology development for optimization of MRI protocols in the clinical and research setting

The American Thrombosis and Hemostasis Network (ATHN)

The Development of Electroencephalography (EEG) as a Biomarker in Clinical Psychiatry Research

The Effect of Heat Intolerance on Exercise and Physical Function

The Effect of Maternal Habitus on Twin Growth and Evaluation of Fetal Anatomy

The Effect of Simple basal Insulin titration, Metformin Plus Liraglutide for Type 2 Diabetes With Very Elevated HbA1c - The SIMPLE Study

The Effect of Simulated Spaceflight on Intracranial Pressure

The Effects of Extended Duration of Long-Chain Polyunsaturated Fatty Acid (LCP)-Supplementation on Cognitive, Visual and Immunological Development in Toddlers

The Effects of Oral Pregabalin on Post-Mastectomy Pain Syndrome following Mastectomy: A Retrospective Review

The Feasibility and Acceptability of Incorporating Electronic Assessment Tools during Outpatient Visits for Patients in the Maintenance Phase of Therapy for Acute Lymphoblastic Leukemia

The GAS study, A multi-site, randomized controlled trial comparing regional and general anesthesia for effects on neurodevelopmental outcome and apnea in infants.

The Glucose Transporter Type I Deficiency (G1D) Registry

The Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE Study)

The Gut Microbiome in Psychiatric Illness

The IDEA Study (Individualized Decisions for Endocrine therapy Alone): A prospective, single-arm cohort study of patients receiving endocrine therapy alone (without radiotherapy) after breast conserving surgery for early-stage, post-menopausal breast cancer patients whose tumors have favorable biologic features

The Impact of Gait Training on the Metabolic Costs of Walking and Cardiorespiratory Capacity in Persons Post Stroke

The Management and Outcome of Gestational Trophoblastic Disease

The Management and Outcome of Invasive/In Situ Cervical Carcinoma

The Management and Outcome of Uterine Cancer

The Medical Arm of Mechanical Circulatory Support (MedaMACS) Study

The Medtronic Melody(R) Transcatheter Pulmonary Valve Post-approval Study

The NEMO trial (NRAS melanoma and MEK inhibitor): A randomized Phase III, open label, multicenter, two-arm study comparing the efficacy of MEK162 versus dacarbazine in patients with advanced unresectable or metastatic NRAS mutation-positive melanoma

The Natural History of CMV-Related Hearing Loss and the Feasibility of CMV Screening as Adjunct to Hearing Screening in Newborns

The Natural History of Stargardt Disease: Prospective Observational Study of Rod Function in Stargardt Disease

The Pediatric ERCP Database Initiative (PEDI)

The Role Mitochondrial Dysfunction in Non-Alcoholic Fatty Liver Disease

The Role of Aldosterone on Augmented Exercise Pressor Reflex in Hypertension

The Role of CAR and its Application in Bladder Cancer

The SENTRY Clinical Study. A Prospective, Multi-Center Study of the Novate Sentry Bioconvertible Inferior Vena Cava Filter.

The Surpass Intracranial Aneurysm Embolization System Pivotal Trial to Treat Large or Giant Wide Neck Aneurysms

The University of Texas Southwestern Cardiology Clinical Research Database (CCRD) and Research Program

The Utility of Atropine in Pediatric RSI - A Change in the Standard of Care

The Utility of Telemedicine in the Management Migraine: A Pilot Study

The effectiveness of contact lens care solutions on Pseudomonas biofilms formed in the presence of neutrophils

The effects of a lipid and of a phosphate meal on serum fibroblast growth factor (FGF) 19 levels and renal phosphate excretion in humans.

The examination of inter-rater reliability of the Child-SCAT3 and the SCAT3 in the pediatric emergency department for the evaluation of sports-related concussions

The impact of ultrasound IV placement on DVT risk

The incidence and significance of a prior cancer diagnosis among patients with lung cancer

The long term impact of walking practice on functional mobility and quality of life in persons with Parkinson Disease

The management and outcome of pre-invasive and invasive vulvar carcinoma

The relationship between brain iron accumulation and beta-amyloid deposition in middle-aged and older adults

The role of cardiovascular insults on aging changes in brain structure and vascular function and their cognitive outcomes.

Therapeutic Hypothermia After Pediatric Cardiac Arrest (THAPCA)

Therapeutic Potential of EffCaMgCit During PPI Use: A Multi-dosing Study

Time Limited Observational Study of Moderately Preterm (29 0/7 [?] 33 6/7 wks)

Tissue Procurement and Outcome Collection for Patients with Head and Neck Tumors

Tissue Procurement and Outcome Collection for Patients with Hematologic Malignancies

Towards Measures of Lupus Nephritis Activity & Damage for Children

Transcranial direct current stimulation (tDCS) in chronic stroke recovery-Pilot

Transfusions of Prematures (TOP) Trial: Does a Liberal Red Blood Cell Transfusion Strategy Improve Neurologically-Intact Survival of Extremely-Low-Birth-Weight Infants as Compared to a Restrictive Strategy?

Transition Readiness and Quality of Life in Patients with Congenital Urologic Conditions

Trial of Continuous Compressions versus Standard CPR in Patients with Out-Of-Hospital Cardiac Arrest

UT Neuropsychiatry Research Program: (DBC)

UT Southwestern Hepatitis Tissue Repository

UT Southwestern Hepatocellular Carcinoma (HCC) Early Detection Study

UT Southwestern Liver Disease Repository and Registry

UTSW SBRT Prospective Clinical Registry for Oligometastic disease, Consolidation therapy, Debulking prior to Chemotherapy, or Re-Irradiation

Ultrasound Findings In Placenta Accreta

Use of the CA-125 Algorithm for the Early Detection of Ovarian Cancer in Low Risk Women

Using Imaging and Computational Tools to Improve Risk Stratification in Children with Bone Cancer

Utility of Natriuretic Peptides in assessing Fluid Responsiveness in children with Shock

Value of Liquid Potassium Magnesium Citrate in Controlling Hypertension

Vascular Effects of Infection in Pediatric Stroke

Vilazodone in Adolescents with Major Depression

Vitamin D Homeostasis in Sarcoidosis

Vitamin D and type 2 diabetes (D2d study)

Vitamin E Supplimentation in Burn Patients

When Is An ICP Transducer Providing A Value Reflecting True ICP? (WAIT A TIC)

Whole Blood Platelet Aggregation in Chronic Kidney Disease on Aspirin and Clopidogrel Study

Zenith(RegisteredTM) TX2(RegisteredTM) Low Profile Endovascular Graft for Blunt Thoracic Aortic Injury Clinical Study

Zenith(RegisteredTM) p-Branch[?] Multicenter Study

`A Phase 1, Multiple-dose, dose-escalation Trial of PT2385 Tablets, A Hif-2(RegisteredTM) Inhibitor, in Patients with Advanced Clear Cell Renal Cell Carcinoma

first trimester ultrasound and placenta accreta

g A Randomized, Controlled Double-blind Study Comparing the Efficacy and Safety of Voclosporin (23.7 mg BID, or 39.5 mg BID) with Placebo in Achieving Remission in Patients with Active Lupus Nephritis