Protein Chemistry Core:
Major Equipment Roster

Peptide Synthesis

Applied Biosystems 433A

Single-peptide, batch synthesizer with Fmoc and t-Boc chemistry capability at a scale of 0.1 to 0.5 mmol.

Applied Biosystems 430A

Single-peptide, batch synthesizer with Fmoc and t-Boc chemistry capability at a scale of 0.1 to 0.5 mmol. Fast cycles allow a 20mer peptide to be synthesized in 8h.

Perseptive Biosystems Pioneer

Fmoc chemistry only, continuous flow instrument, which will synthesize two peptides simultaneously.

Rainin Symphony

Multiple-peptide synthesizer using batch-synthesis methodology and either Fmoc or t-Boc chemistry. Up to 12 peptides can be synthesized simultaneously.

Advanced Chemtech APEX396

Multiple-peptide synthesizer using batch-synthesis methodology and either Fmoc or t-Boc chemistry. Number of peptides that can be synthesized at one time depend on the RV block used and the desired synthesis scale.

Peptide Institute Hydrogen Fluoride Apparatus

Permits safe handling of HF required for final cleavage and deprotection of t-Boc synthesized peptides.

Mass Spectrometry

Waters LR Reflectron MALDI-TOF

High-sensitivity, high-resolution MALDI-TOF with reflectron capability.

Protein Sequencing

Applied Biosystems 494

We have two 4-channel Edman protein sequencers, one of which is dedicated for handling 32P-labeled samples.