Texas Institute for Brain Injury and Repair 

The Texas Institute for Brain Injury and Repair at UT Southwestern Medical Center (TIBIR) is a comprehensive and transformative approach to how brain injuries are prevented and treated. We will draw on our depth of technology advances, innovative research, and exemplary patient care as part of a unique collaboration to enhance the treatment and diagnosis of brain injuries.

Latest News

Spring 2015 TIBIR Pilot Grant Awardees

Levi Good, Ph.D., Instructor of Neurology and Neurotherapeutics
“A longitudinal study of electrophysiological and histological correlates of repeated mild traumatic brain injury”

John Hart, M.D., Professor of Neurology and Neurotherapeutics and Psychiatry
“Transcranial Direct Cortical Stimulation for TBI”

Lakshmi Raman, M.D., Assistant Professor of Pediatrics
“Maintenance of CPP in moderate to severe traumatic brain injury attenuates CNS inflammation after TBI”

Yingfei Wang, Ph.D., Assistant Professor of Pathology and Neurology and Neurotherapeutics
“The role of a novel nuclease PAAN1 in traumatic brain injury”

Rong Zhang, Ph.D., Associate Professor of Internal Medicine and Neurology and Neurotherapeutics
“Aerobic Exercise as a Treatment for TBI”


North Texas Sports Concussion Registry Study (CON-TEX) opens for enrollment

The CON-TEX study is designed to capture comprehensive, longitudinal data on sports-related concussion and mild TBI subjects. The data will give a “snapshot” of the current state of concussion assessment and treatment in youth athletes in the Dallas-Fort Worth area, a highly relevant, understudied population. The information gathered will be the foundation on which the design of rigorous clinical research and valuation of treatments will be built. Individuals enrolled in the registry will have the opportunity to participate in future clinical trials testing innovative therapies and diagnostic approaches. Learn more.


TIBIR funding leads to discovery of connection between concussions in NFL players and brain changes later in life

Dr. John Hart, lead investigator for the study (on left), and Dr. Munro Cullum, a study co-author.
(l–r)John Hart, M.D., lead investigator for the study (on left), and Munro Cullum, Ph.D., a study co-author.

In the first study of its kind, former National Football League (NFL) players who lost consciousness due to concussion during their playing days showed key differences in brain structure later in life. The findings were reported in JAMA Neurology, and they represent the first study to compare the relationship between hippocampal volume, memory performance, and concussion severity. Read more.


Texas Institute for Brain injury and Repair acquires TissueCyte 1000 microscopes

The microscopes are the latest generation in serial two-photon laser imaging, and are the centerpiece of TIBIR's new Whole Brain Microscopy Facility. The facility will be a major resource for scientists researching traumatic brain injury and neurodegenerative diseases.  Read more.

UT Southwestern’s Dr. Julian Meeks (right) and Dr. Denise Ramirez view a tissue sample at one of two new TissueCyte 1000 microscopes, the only ones of their kind in Texas and two of just a handful in existence around the world.
UT Southwestern’s Julian Meeks, Ph.D., (right) and Denise Ramirez, Ph.D., view a tissue sample at one of two new TissueCyte 1000 microscopes.

TIBIR funding propels research, leads to additional funding and publication

Jenny Hsieh, Ph.D., (middle), one of the first recipients of a grant from TIBIR, has been awarded R01 and R21 grants in addition to a DoD Discovery Award. Dr. Hsieh says the support from TIBIR led to the additional grants by allowing her lab to complete work on aberrant neurogenesis in epilepsy. Her research was published in Nature Communications.

Jenny Hsieh, Ph.D.(middle) and her team, graduate student Rebecca Brulet (far left) and Visiting Assistant Professor Kyung-Ok Cho, Ph.D. (far right). Missing: Zane Lybrand (Postdoc) and Farrah Tafacory (Masters Student, UT Dallas).
Jenny Hsieh, Ph.D.(middle) and her team, graduate student Rebecca Brulet (far left) and Visiting Assistant Professor Kyung-Ok Cho, Ph.D. (far right). Missing: Zane Lybrand (Postdoc) and Farrah Tafacory (Masters Student, UT Dallas).