Juan Pascual, MD

Assistant Professor

Recent Publications Pascual JM, Wang D, Yang R, Shi L, Yang H, De Vivo DC. , "Structural signatures and membrane helix 4 in GLUT1: inferences from human blood-brain glucose transport mutants " J Biol Chem , 283(24): 16732-42 , June 2008

Pascual JM, Wang D, Hinton V, Engelstad K, Saxena CM, Van Heertum RL, De Vivo DC. , "Brain Glucose Supply and the Syndrome of Infantile Neuroglycopenia " Arch. Neurol , : , 2007

Wang D, Pascual JM, Yang H, Engelstad K, Mao X, Cheng J, Yoo J, Noebels JL, De Vivo DC. , "A mouse model for Glut-1 haploinsufficiency " Hum. Mol. Genet. , 15: 1169-79 , 2006

Pascual JM. , "Fever, molecular excitability and epilepsy " Neurosci. Lett. , 368: 1 , 2004

Significant Publications
J. M. Pascual, C.C. Shieh, G. E. Kirsch, A.M. Brown , "K+ pore structure revealed by reporter cysteines at inner and outer surfaces " Neuron , 14: 1055-1063 , 1995

J. M. Pascual, A. Karlin , "State-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor " J. Gen. Physiol. , 111: 717-739 , 1998

J. M. Pascual, A. Karlin , "Delimiting the binding site for quaternary ammonium lidocaine derivatives in the acetylcholine receptor channel " J. Gen. Physiol. , 112: 611-621 , 1998

J. M. Pascual, D. Wang, R.L. van Heertum, K. Engelstad, D.C. De Vivo , "Imaging the footprint of Glut1 deficiency on the brain " Ann. Neurol. , 52: 458-464 , 2002

Pascual JM, Wang D, Lecumberri B, Yang H, Mao X, Yang R, De Vivo DC. , "GLUT1 deficiency and other glucose transporter diseases " Eur. J. Endocrinol. , 150: 627-33 , 2004