Matthew Porteus, MD

Assistant Professor

Recent Publications Porteus, MH, Cathomen, T, and Baltimore, D , "Efficient Gene Targeting Mediated by AAV and DNA Double-Strand Breaks " Cell Biol , 23/10: 3558-3565 , 2003

Urnov, Miller, Lee, Beausejour, Rock, Augustus, Jamieson, Porteus, Gregory, and Holmes , "Highly efficient endogenous human gene correction using designed zinc-finger nucleases " Nature , 435: 646-651 , 2005

Porteus, MH, and Baltimore, D , "Chimeric Nucleases Stimulate Gene Targeting in Human Cells " Science 300 , : 763 , 2003

Urnov, Miller, Lee, Beausejour, Rock, Augustus, Jamieson, Porteus, Gregory, and Holmes , "Highly efficient endogenous human gene correction using designed zinc-finger nucleases " Nature , 435: 646-651 , 2005

Pruett-Miller, Connelly, Maeder, Joung, and Porteus , "Comparison of Zinc Finger Nucleases for Use in Gene Targeting in Mammalian Cells " Molecular Therapy , 16: 707-717 , 2008

Pruett-Miller, Reading, Porter, and Porteus , "Attenuation of Zinc Finger Nuclease Toxicity by Small Molecule Regulation of Protein Expression " PLoS Genetics , 5: e1000376 , 2009

Significant Publications
Porteus, MH, Brice AEJ, Bulfone, A, Usdin, TB, Ciaranello, RD, and Rubenstein, JLR , "Isolation and characterization of a library of cDNA clones that are preferentially expressed in the embryonic telencephalon " Mol Brain Res , 12: 7-22 , 1992

Porteus, MH, Bulfone, A, Ciaranello, RD, and Rubenstein, JLR , "Isolation and characterization of a novel cDNA clone encoding a homeodomain that is developmentally regulated in the ventral forebrain " Mol Brain Res , 7: 221-229 , 1991

Porteus, MH, Bulfone, A, Puelles, L., Liu, JK, Puelles L, Lo, L-C, and Rubenstein, JLR , "Dlx-2, Mash-1, Map-2 expression and bromodeoxyuridine incorporation define molecularly distinct cell populations in the embryonic mouse forebrain " J Neuroscience , 14/11: 6370-9383 , 1994