Philip Shaul, MD
Professor
Recent Publications
Seetharam D, Mineo C, Gormley AK, Gibson LL, Vongpatanasin W, Chambliss KL, Hahner LD, Cummings ML, Kitchens RL, Marcel YL, Rader DJ, Shaul PW ,
"High density lipoprotein promotes endothelial cell migration and reendothelialization via scavenger receptor-B type I "
Circ. Res. ,
98:
63-72 ,
2006
Vongpatanasin W, Thomas GD, Schwartz R, Cassis LA, Osborne-Lawrence S, Hahner L, Gibson LL, Black S, Samols D, Shaul PW ,
"CRP causes downregulation of vascular AT2 receptors and systolic hypertension in mice "
Circulation ,
115:
1020-1028 ,
2007
Kumar P, Tall GG, Chambliss KL, Yuhanna IS, Wu Q, Mumby SM, Mineo C, Shaul PW ,
"Direct interactions with Galpha i and Gbeta-gamma mediate nongenomic signaling by ERalpha "
Mol. Endocrinol. ,
21:
1370-1380 ,
2007
Schwartz R, Osborne-Lawrence S, Hahner L, Gibson LL, Gormley AK, Vongpatanasin W, Zhu W, Word RA, Seetharam D, Black S, Samols D, Mineo C, Shaul PW ,
"CRP downregulates endothelial NO synthase and attenuates reendothelialization in vivo in mice "
Circ. Res. ,
100:
1452-1459 ,
2007
Umetani M, Domoto H, Gormley AK, Yuhanna IS, Cummins CL, Liverman AB, Javitt NB, Shaul PW, Mangelsdorf DJ ,
"27-Hydroxycholesterol is an endogenous selective estrogen receptor modulator that inhibits the cardiovascular effects of estrogen "
Nat. Med. ,
:
,
2007
Significant Publications
Chen Z, Yuhanna IS, Galcheva-Gargova Z, Karas RH, Mendelsohn ME, Shaul PW ,
"Estrogen receptor alpha mediates nongenomic activation of eNOS by estrogen "
J. Clin. Invest. ,
130:
401-406 ,
1999
Yuhanna IS, Zhu Y, Cox BE, Hahner LD, Osborne-Lawrence S, Lu P, Anderson RGW, Mendelshoh ME, Hobbs HH, Shaul PW ,
"High density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase "
Nature Med. ,
7:
853-857 ,
2001
Shaul PW, Smart EJ, Robinson LJ, German Z, Yuhanna IS, Ying Y, Anderson RGW, Michel T ,
"Acylation targets endothelial nitric oxide synthase to plasmalemmal caveolae "
J. Biol. Chem. ,
271:
6518-6522 ,
1996
Assanasen C, Mineo C, Seetharam D, Yuhanna IS, Marcel YL, Connelly MA, Williams DL, de la Llera-Moya M, Shaul PW, Silver DL ,
"Cholesterol binding, efflux and a PDZ-interacting domain of SR-BI mediate HDL-initiated signaling "
J. Clin. Invest. ,
115:
969-977 ,
2005
Mineo C, Gormley AK, Yuhanna IS, Osborne-Lawrence S, Gibson LL, Hahner L, Shohet RV, Black S, Salmon JE, Samols D, Karp DR, Thomas GD, Shaul PW ,
"FcRIIB mediates C-reactive protein inhibition of endothelial NO synthase "
Circ. Res. ,
97:
1124-1131 ,
2005
