Christopher Lu, MD

Professor

Recent Publications Lu, C.Y. and Senitko, M. , "The inflammatory response to ischemic acute renal injury. " Seldin and Giebisch?s The Kidney: Physiology and Pathophysiology. Academic Press. Ed. Alpern, R.J. and Hebert, S.C. Fourth edition. Academic Press. , : 2577-2590 , 2008

Kielar, M.L.; John, R.; Bennett, M.; Richardson,J.A.; Shelton, J.M.; Chen, L.; Jeyarajah, D.R.; Zhous, X.J.; Zhou, H.; Chiquett, B.; Nagami, G.T.; Lu, C. Y. , "The maladaptive role of interleukin 6 in ischemic acute renal failure. " J. Am. Soc. Nephrol. , 16: 3315-3325 , 2005

Zhang, Y., Woodward, V. K., Shelton, J. M., Richardson, J. A., Link, D. C., Zhou, X. J., Kielar, M. L., Jeyarajah, D. R. and Lu, C. Y. , "Ischemia/ reperfusion induces G-CSF gene expression by renal medullary thick ascending limb cells in vivo and in vitro. " Am J. Physiol - Renal Physiology , 286: F1193-201 , 2004

Wang, Y. ......Lu, C. Y. , "An early proinflammatory signal in ischemic AKI is expression of interferon-regulatory-factor-1 by proximal tubules " J Am Soc Nephrol , 2009 in press: , Spring 2009

Significant Publications
Lu, C.Y., Calamai, E.G. and Unanue, E.R. , "A defect in the antigen-presenting function of macrophages from neonatal mice. " Nature , 282: 327-329 , 1979

Redline, R.W. and Lu, C.Y. , "The role of local immunosuppression in murine fetoplacental listeriosis. " J. Clin. Invest. , 79: 1234-1241 , 1987

Penfield, J.G., Y.Wang, S. Li, M.A. Kielar, S.C. Sicher, D.R. Jeyarajah, and Lu, C.Y. , "Injury from transplant surgery recruits recipient MHC Class II-positive leukocytes, including dendritic cells, into the transplanted kidney in a rat model where there is no rejection. " Kidney International , 56: 1759-1769 , 1999

Lu, C.Y., Penfield, J.G., Kielar, M.L., Vazquez, M.A., Jeyarajah, D.R , "Perspectives in basic science: Hypothesis: is renal allograft rejection initiated by the response to injury sustained during the transplant process? " Kidney International , 55: 2157-2168 , 1999

Lu, C.Y., J Hartono, M. Senitko, J. Chen. , "The inflammatory response to ischemic acute kidney injury: a result of the ?right stuff? in the ?wrong place.? " Current Opinion in Nephrology & Hypertension , 16 (2): 72-89 , 2007