2015 News Releases

Gene-editing technique successfully stops progression of Duchenne muscular dystrophy

Gene-editing technique successfully stops progression of Duchenne muscular dystrophy

 

Using a new gene-editing technique, a team of scientists from UT Southwestern Medical Center stopped progression of Duchenne muscular dystrophy (DMD) in young mice.

Structure of protein family that has been implicated in disease development identified

Structure of protein family that has been implicated in disease development identified

 

UT Southwestern Medical Center researchers – along with colleagues at the University of Pennsylvania – have determined the first atomic structure of a protein from the two-pore channel (TPC) family.

International team of scientists detect inherited traits tied to sleep, wake, and activity cycles associated with severe bipolar disorder

International team of scientists detect inherited traits tied to sleep, wake, and activity cycles associated with severe bipolar disorder

 

Researchers here found that those with bipolar disorder awoke later and slept longer, on average were awake fewer minutes overall, and were active for shorter periods than those without the disorder.

Cell model of Lou Gehrig’s disease to aid in search for more effective drug therapies

Cell model of Lou Gehrig’s disease to aid in search for more effective drug therapies

 

There are no effective drugs to treat this disease, which is also known as amyotrophic lateral sclerosis or ALS, primarily because scientists lack an appropriate cell model of the disease.

Scientists discover a new role for RNA in safeguarding chromosome number in human cells, with implications for cancer biology

Scientists discover a new role for RNA in safeguarding chromosome number in human cells, with implications for cancer biology

 

UTSW molecular biologists have identified a gene called NORAD that helps maintain the proper number of chromosomes in cells, and that when inactivated, causes the number of chromosomes in a cell to become unstable, a key feature of cancer cells.

Liver hormone works through brain’s reward pathway to reduce preference for sweets, alcohol

Liver hormone works through brain’s reward pathway to reduce preference for sweets, alcohol

 

A liver hormone works via the brain’s reward pathway to reduce cravings for sweets and alcohol in mammals, UT Southwestern Medical Center researchers have found.

Dr. Alfred G. Gilman, UTSW Nobel Laureate: 1941-2015

Dr. Alfred G. Gilman, UTSW Nobel Laureate: 1941-2015

 

Nobel Laureate Dr. Alfred G. Gilman, former Chairman of Pharmacology and Dean of the UT Southwestern Medical School, as well as former Executive Vice President for Academic Affairs and Provost at UT Southwestern Medical Center, died on Dec. 23, 2015.

UT Southwestern establishing Wellstone Muscular Dystrophy Center to further research for new treatments using gene-editing technique

UT Southwestern establishing Wellstone Muscular Dystrophy Center to further research for new treatments using gene-editing technique

 

The National Institutes of Health has awarded UT Southwestern Medical Center researchers a $7.8 million grant to establish a Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center, one of six nationally.

UT Southwestern selected to join Pulmonary Fibrosis Foundation’s Care Center Network

UT Southwestern selected to join Pulmonary Fibrosis Foundation’s Care Center Network

 

UT Southwestern Medical Center’s Pulmonary Fibrosis Program is one of 40 programs nationally – and the only one in North Texas – to be selected to be part of the Pulmonary Fibrosis Foundation Care Center Network.

Scientists identify mechanisms to reduce epileptic seizures, and restore brain function and memory following traumatic brain injury

Scientists identify mechanisms to reduce epileptic seizures, and restore brain function and memory following traumatic brain injury

 

UT Southwestern Medical Center researchers have found that halting production of new neurons in the brain following traumatic brain injury can help reduce resulting epileptic seizures, cognitive decline, and impaired memory.