UT Southwestern in the News — May 2010

KXAS-TV (NBC5) – Scans with lower radiation doses (May 28, 2010)
The latest-generation CT scan is faster, easier for doctors to read and, apparently, safer. For years, CT scans have diagnosed medical conditions deep beneath the skin. With patients sounding the alarm about high levels of radiation, hospitals are scrambling for new technology. UT Southwestern rolled out a scanner that lowers radiation by a third. Scan time is under a minute; older scanners take several minutes. Dr. Ed Stehel, assistant professor of radiology, said physicians can get diagnostic information to work stations quicker to interpret the exam.

R&D Magazine – UT Southwestern researchers use novel sperm stem-cell technique to produce genetically modified rats (May 28, 2010)
For two decades, the laboratory mouse has been the workhorse of biomedical studies and the only mammal whose genes scientists could effectively and reliably manipulate to study human diseases and conditions. Now researchers at UT Southwestern ave added another experimental research animal to the scientific stable: the rat. In a new study appearing in the June issue of Nature Methods, UT Southwestern researchers detail how they created 35 new rat "lines," with each type of animal harboring mutations in specific genes. Dr. Kent Hamra, assistant professor of pharmacology and lead author of the study, comments. Read More

KERA FM 90.1 (National Pubic Radio) – New CPR method saving lives (May 27, 2010)
Carrollton paramedics are among North Texas first-responders in the Resuscitation Outcomes Consortium, known as ROC. It's a multi-year study designed to improve cardiac survival rates. Dr. Ahamed Idris, director of Emergency Medicine Research at UT Southwestern, says paramedics have changed the way they performed CPR: doing continuous chest compressions instead of "mouth to mouth" resuscitation. Listen

KDFW-TV (FOX) CH 4 – Teen on Mend after Horrific Boat Accident (May 27, 2010)
Kristen Kilpatrick was maimed in a boating accident about one year ago, but the North Texas teenager has made an incredible recovery, thanks to reattachment surgery. The 19-year-old TCU student lost most of her right arm when she fell off the family boat and was hit by the propeller. However, Dr. Joseph Borrelli, a surgeon at UT Southwestern, reattached her severed limb, and physical therapy is helping Kilpatrick learn to again move her arm.

Women's Health Magazine – How to deal with depression (May 26, 2010)
Though there are no hard stats, anecdotal evidence suggests that women are increasingly treating antidepressants like Advil: We go on them when we feel bad, stop when we feel better (or when the side effects bum us out), and go on them again if the blues come back. But new research shows that an on-again, off-again relationship with antidepressants can have far more repercussions than anyone realized. When you toss your pills, says Madhukar Trivedi, M.D., a leading depression researcher at the Mood Disorders Research Program and Clinic at UT Southwestern, "you run the risk that if your depression comes back, the same treatment won't work." Read More

WFAA-TV (CH 8) – Fort Worth police chief promotes hormone therapy (May 25, 2010)
Sex drive. Mental focus. Energy. All were topics of discussion at a recent voluntary Wellness Seminar for Fort Worth police officers. Chief Jeffrey Halstead called the meeting to share his testimony about testosterone. He said he didn't have enough, and hit rock bottom, until he was treated with hormone therapy. UT Southwestern endocrinologist Dr. Richard Auchus says the Chief is encouraging a socially acceptable form of narcotics. Watch Video

KDAF-TV (Ch 33) – TCU student nearly 100 percent recovered after doctor re-attaches arm (May 21, 2010)
To ever move her fingers again seemed unlikely for 19- year-old Kristen Kilpatrick. One year ago, Kristen was fishing with friends in Erath County when the boat she was on lurched forward and sent her into the chilly morning water. The two story pontoon boat ran over her, and at the other end the propeller sliced into her right arm. "All I kept saying was I don't believe it," Kristen said. "I don't have an arm, I don't have an arm." Kristen had lost a lot of blood and there was concern she wouldn't survive the 100 mile air ambulance flight to Parkland Hospital. UT Southwestern orthopedic surgeon Dr. Joseph Borrelli was on call at Parkland that night.

Dallas Morning News – Simmonses' gift honors Paul Bass (May 24, 2010)
Philanthropists Annette and Harold Simmons, who have already donated nearly $178 million to UT Southwestern Medical Center, have given $2 million more through the Southwestern Medical Foundation to honor the couple's friend Paul M. Bass Jr. Bass, vice chairman of First Southwest Co., died in March at age 74. He served 13 years as chairman of Southwestern Medical Foundation and spent three decades as a civic volunteer dedicated to improving health care in Dallas. The new endowment will support the Paul M. Bass Center for Neurosurgical Innovation, which will be part of the Harold and Annette Simmons Comprehensive Center for Research and Treatment in Brain and Neurological Disorders. Read More

Los Angeles Times – Rodent of the Week: Male fat is different from female fat (May 21, 2010)
Men often carry extra weight on their stomachs while women tend to accumulate fat on the butt, hips and thighs. A new mouse study suggests why: It seems that female fat tissue and male fat tissue behave very differently. Researchers at UT Southwestern examined mouse genes (fat distribution in mice is similar to humans) and found only 138 genes that were common to both male and female fat cells. That means that fat on men is governed by a largely different gene expression profile than fat on women. The discovery of distinct male and female fat genes might yield clues to understanding what happens after menopause, said Dr. Deborah Clegg. Read More

KDAF-TV (CH 33) – Student with cochlear implant overcomes challenges (May 21, 2010)
Chirping birds is a sound that Michael Noble doesn't take for granted. Michael was born deaf, and at the age of two became the first child in north Texas to have cochlear implant surgery at UT Southwestern. Michael went through years of intense speech therapy and decided in the 7th grade he wanted to go Southern Methodist University, where he breezed through in just three years and graduated last weekend. UT Southwestern assistant professor Dr. Walter Kutz, who implants about four kids a month, comments.

KXAN-TV (NBC) CH 5 – Smart snacking on the run (May 21, 2010)
There are some choices at the drive-through that won't wreck your diet. Bernadette Latson, a registered dietician at UT Southwestern, says some of these options may be OK in snack form. "Just like your money, you can decide how you're going to spend your calories," she says. Latson says a snack calorie count under 200 is a good limit. Read More

United Press International – Male, female fat cells different in mice (May 20, 2010)
Genes dictate if fat is stored on belly or hips — in particular, gender genes, U.S. researchers said. Researchers at UT Southwestern, who studied mice, say they were surprised to find major differences between male and female fat cells. "We found that out of about 40,000 mouse genes, only 138 are commonly found in both male and female fat cells," senior author Dr. Deborah Clegg said. "This was completely unexpected. We expected the exact opposite — that 138 would be different and the rest would be the same between the sexes." Read More

Dallas Morning News – Rise in cases leaves Dallas-area abused kids waiting for help (May 16, 2010)
The Children's Advocacy Center says it cannot keep up with the growing number of children who need counseling after suffering physical or sexual abuse. Even after adding another counselor, the center — which handles Dallas cases referred through Child Protective Services — has had to place children on a waiting list because of increases in the past five months. Dr. Matthew J. Cox, medical director for REACH and assistant professor of pediatrics at UT Southwestern, comments. Read More

Science Daily – Belly fat or hip fat: It really is all in your genes, says researcher (May 16, 2010)
The age-old question of why men store fat in their bellies and women store it in their hips may have finally been answered: Genetically speaking, the fat tissue is almost completely different. Dr. Deborah Clegg, assistant professor of internal medicine at UT Southwestern and senior author of the study appearing in the International Journal of Obesity, comments. Read More

Dallas Morning News – Over-the-counter DNA kit worries genetics experts (May 14, 2010)
The FDA challenged San Diego-based Pathway Genomics for failing to get its genetic-test kit reviewed by the federal agency before taking it to the marketplace. Experts in genetic testing, both local and national, were relieved that the test was pulled. UT Southwestern's Dr. David Euhus comments. Read More

WFAA-TV (ABC) CH 8 – UT Southwestern team may have found breakthrough in E. coli battle (May 13, 2010)
UT Southwestern researchers say they've made a huge breakthrough that could one day keep E. coli from ever reaching the table. For four years, Dr. Vanessa Sperandio, with
UT Southwestern, has been working with cow samples to figure out how to prevent the spread of food-borne illnesses, like E. coli. The focus is on EHEC, a strain of E. coli found in 70 to 80 percent of cattle. While it won't hurt the animal, it can make people deathly ill. Sperandio and her team now believe the answer lies within a chemical in cows. Watch Video

Dallas Morning News – Pump enriching lives of end-stage heart patients (May 13, 2010)
In January, the Food and Drug Administration approved the use of the mechanical heart pump for advanced heart-failure. As few as 20,000 or as many as 500,000 Americans, most of them elderly, could benefit annually from the pump or future versions of it. Three local medical centers — Medical City, UT Southwestern and Baylor University — began offering the HeartMate II pump to end-stage heart-failure patients this year. Dr. Dan M. Meyer, a cardiothoracic surgeon, implanted 25 heart pumps at Baylor and
UT Southwestern last year and expects to double that this year. However, elderly patients also have been known to resist the pump. Dr. Mark Drazner, a cardiologist and medical director of UT Southwestern's heart-failure and transplant program, also comments. Read More

KTVT-TV (CBS) CH 11 – Eye procedure clearing childhood cataracts (May 13, 2010)
When thinking about cataracts, most people admit they think of senior citizens. But hundreds of babies are born with cataracts each year. Doctors in North Texas are using cutting edge technology to help children see from an early age, but the procedure has been questioned by some in the medical profession for implanting acrylic lenses in the eyes of infants. The American Medical Association's Archive of Ophthalmology recently published a study on the procedure, including input from a local doctor and families. Dr. David Weakley, director of Division of Ophthalmology at Children's Medical Center in Dallas and Plano, as well as a professor at UT Southwestern, comments.

KTVT-TV (CBS) CH 11 – State grant increasing Fort Worth colon screenings (May 13, 2010)
Turning 50 means the AARP sends you a card in the mail and your doctor tells you it's time for a colonoscopy. While early detection saves lives, screenings among the uninsured at John Peter Smith Hospital are low. A $900,000 research grant from the Cancer Prevention and Research Institute should help. Dr. Keith Argenbright, an associate professor at UT Southwestern and the medical director at the Moncrief Cancer Institute, said, "We're reaching out to these patients calling them up and inviting them to a colonoscopy or a home colon testing kit." The Moncrief Cancer Institute, UT Southwestern and JPS are together on the project that will randomly select candidates for the colon cancer screening program from JPS.

KTVT-TV (CBS) CH 11 – DNA testing kits to hit Walgreens shelves soon (May 12, 2010)
The largest U.S. drugstore chain, Walgreen Co., will start selling genetic testing kits at many of its stores later this month. But some doctors have serious ethical concerns about the kits, especially if the results are wrong. For instance, a genetic predisposition to Alzheimer's is rare, and a simple DNA test is likely to miss other indicators. "What if somebody says, 'I don't want to live with Alzheimer's disease, I'd rather die'? And so at the age of 45, he kills himself," asked Dr. Myron Weiner, an Alzheimer's expert at
UT Southwestern. Linda Robinson, a genetic counselor at UT Southwestern, said, "One of the concerns we have about this type of testing is that if a person tests negative for just one of the markers for breast cancer, they would assume that they're not going to get the disease and they would not follow up with normal cancer surveillance, such as mammograms."

Dallas Morning News – On-field injury leads to teen baseball player's cancer diagnosis (May 10, 2010)
At the edge of the baseball field, a slight young man in black shorts and T-shirt whipped a baseball around with members of the Royse City Bulldogs. Just a couple of weeks earlier doctors worked on Jake Owen's ruptured spleen following an on-field collision. Kari Owen remembered their terrifying diagnosis, and the last thing she wanted was for her 15-year-old son to suffer any more pain. Doctors there discovered that Jake's internal bleeding was coming from his spleen — and that he had not one spleen, but three, his mother said. During routine blood tests before surgery, doctors also found the cause of the enlarged spleen. Jake had chronic myelogenous leukemia. Dr. Robert Collins, a professor of internal medicine specializing in hematologic malignancies and bone marrow transplants at UT Southwestern, comments. Read More

United Press International – Nausea may be flu, not morning sickness (May 9, 2010)

U.S. doctors warn nausea and vomiting, especially after the first trimester, may be signs of flu. Researchers at UT Southwestern found nausea and vomiting — usually signs of flu in children but not in adults — were common in pregnant women with flu. "Both physicians and patients should be aware of these findings so treatment is not delayed," study lead author Dr. Vanessa Rogers said in a statement. "I think our findings should encourage people to be vigilant and to take symptoms seriously." Read More

Fort Worth Business Press – UTA professor developing nanomedicine for cancer (May 9, 2010)
Wei Chen, assistant physics professor at UT Arlington, has a background in chemistry. And although he’s in the physics department, he’s actually working on nanomedicine research. Looking for a possible future cancer treatment, Chen works with others from diverse areas. Dr. Keith Argenbright, associate professor at UT Southwestern and medical director of the affiliated Moncrief Cancer Institute, comments. Read More

Wall Street Journal – When a c-section makes sense (May 4, 2010)
Medical experts say many c-sections-which involve delivering a baby through a surgical incision-are performed unnecessarily. "There is no question we're doing a lot more
c-sections than necessary," says Bruce Meyer, executive vice president for health system affairs and professor in the department of obstetrics and gynecology at UT Southwestern. He says several factors including doctors' fear of litigation, a growing demand among patients for elective caesareans that aren't medically necessary and more induced labors have contributed to the growing rates of c-sections. Read More

Dallas Morning News – 5 ways parents can keep their kids well (May 4, 2010)
Parents always want to listen to the pediatrician when a child is sick. But what do the pediatricians want parents to hear when the goal is to keep children well? That's the question we posed to three doctors, including Dr. Joel B. Steinberg, professor of pediatrics at UT Southwestern and attending physician at Children's Medical Center Dallas. Steinberg says 80 percent of kids younger than a year old regularly eat french fries — a food he'd like to see less of in children's diets along with macaroni and cheese, mashed potatoes, fried and other high-fat foods, and high-sugar drinks. Steinberg respects the anxiety that some parents express about possible links between vaccines and autism, even though no such connections have been proven. He suggests discussing concerns with your child's pediatrician, who should be up to speed on the latest research. Read More

CNN – Obese kids more vulnerable to bullies (May 4, 2010)
Children in grades 3 through 6 who are obese are more likely to be bullied than their normal-weight peers, a new study has found. Positive interactions with parents may help prevent bullying in the first place, according to another new study, presented today at the annual meeting of the Pediatric Academic Societies in Vancouver, B.C. In that study, researchers at UT Southwestern analyzed data from the 2007 National Survey of Children's Health, which included more than 45,000 parents of children between the ages of 10 and 17. Children whose parents shared ideas and talked often with them were about 40 percent less likely to bully other children compared to the children of parents who said they didn't do those things regularly. On the other hand, the children of parents who said they are often angry with them or who feel bothered by them were up to three times more likely to be bullies, according to the study. Read More

Bloomberg/Business Week – Involved parents less likely to raise bullies (May 4, 2010) 
Parents can play an important role in preventing their children from becoming bullies by helping them with homework and getting to know their friends, a new study suggests. "Improving parent-child communication and parental involvement with their children could have a substantial impact on child bullying," said study author Dr. Rashmi Shetgiri, a pediatrician and researcher at UT Southwestern and Children's Medical Center in Dallas. Shetgiri and colleagues analyzed a 2007 national survey of 45,897 parents with children aged 10 to 17. Among other things, the survey asked whether the children were bullies. About 15 percent of children were identified as bullies. Read More