Awards for May 2017

Federal Awards

Ahmad, Zahid, NIH, Molecular Basis of Autosomal Dominant Hypercholesterolememia in Multiethnic Cohort, $186,814; Amatruda, James, Children’s Hosp of Phila/NIH, Solid Malignancy Integrated Translational Science Center, $13,438; Boothman, David, NIH, Use of Beta-lapachone for Lung Cancer Chemotherapy, $301,626; Brekken, Rolf, Houston Methodist Resch Inst/NIH, Effects of VEGF and Collagen Signaling on Biodistribution of TAMs in PDAC, $18,737; Burma, Sandeep, NIH, Mechanisms of EXO1 Regulation in Response to Radiation-Induced DNA Damage, $288,684; Cao, Dian, NIH, Autophagy in Metabolic Distress and Cardiac Function: Regulation by the HDAC-FoxO, $132,097;

Deberardinis, Ralph, NIH, Metabolic Regulators of Tumor Cell Growth, $346,275; Deberardinis, Ralph, Emory Univ/NIH, Signaling and Targeting of 6-Phosphogluconate Dehydrogenase in Human Cancers, $21,137; Deberardinis, Ralph, Univ of Cincinnati/NIH, Metabolic Adaptive Responses in Cancer, $16,642; Fu, Yang-Xin, Univ of NC/NIH, Novel Therapeutic Approaches to Treating Chronic Hepatitis B Virus Infection, $45,767; Garcia, Christine, NIH, Pulmonary Fibrosis and Telomerase Dysfunction, $401,848; Gardner, Lisa (Fellow A. Shaikh), Natl Science Fdn, Graduate Research Fellowship Program, $46,000; Gardner, Lisa (Fellow M. McDaniel), Natl Science Fdn, Graduate Research Fellowship Program, $46,000; Gardner, Lisa (Fellow W. Costello), Natl Science Fdn, Graduate Research Fellowship Program, $46,000;

Gerber, David, NIH, Development of New Cancer Treatments and Investigators, $167,279; Glass, Donald, NIH, Investigating the Causes of Keloid Formation, $166,320; Goldstein, Joseph, NIH, Molecular Basis of Cholesterol Metabolism, $8,575,351; Huang, Jun-Shen, NIH, JAK2 Signaling in Erythropoiesis, $397,500; Husain, Mustafa, Columbia Univ/NIH, Treatment of Psychosis and Agitation in Alzheimer's Disease, $121,500; Jiang, Jin, NIH, Cell Signaling in Development and Regeneration, $774,198; Lehrman, Mark, NIH, The N-Glycosylation Pathway and Signaling by Free Mannose-6-Phosphate, $372,061; Levine, Benjamin (Fellow C. Hearon), NIH, Abnormal Vascular, Metabolic, and Neural Function During Exercise in HFpEF, $56,694;

Otwinowski, Zbyszek, NIH, Accurate Measurements of Phasing Signal to Determine Macromolecular Structures, $329,825; Patel, Vishal, NIH, MicroRNAs: New Regulators of Disease Progression in Polycystic Kidney Disease, $328,050; Phelan, Herbert, Univ of Wisconsin/NIH, Communication Tool to Assist Severely Injured Older Adults, $46,039; Punaro, Marilynn, Baylor Scott & White/NIH, Center for Lupus Research, $112,517; Raskin, Philip, Univ of S. Florida/NIH, Type 1 Diabetes TrialNet Data Coordinating Center, $256,645; Rypma, Bart, NIH, BOLD and its Discontents: Age-Differences in the Neurophysiology of fMRI Signal, $295,569; Scherer, Philipp, NIH, White Adipose Tissue Physiology, Mitochondrial Function and Adiponectin, $417,852; Scherer, Philipp, Yale Univ/NIH, Metabolic Markers and Predictors of Childhood Obesity, $21,156;

Schmid, Sandra, NIH, Mechanisms Regulating Clathrin-Mediated Endocytosis, $375,360; Shaul, Philip, Univ of Cincinnati/NIH, Role of Endothelial and Macrophage ApoER2, $347,000; Shay, Jerry (Fellow A. Ludlow), NIH, Manipulating hTERT Splicing in Lung Cancer Cells, $144,720; Skapek, Stephen, Children’s Hosp of Phila/NIH, Solid Malignancy Integrated Translational Science Center, $34,766; Street, Nancy, UT El Paso/NIH, BUILDing Scholars – Research Enrichment Core, $60,926; Tiro, Jasmin, NIH, Developing a Self-Persuasion Intervention Promoting Adolescent HPV Vaccination, $352,522; Toto, Robert, NIH, UTSW Center for Translational Medicine UL1, $4,981,558; Toto, Robert, NIH, UTSW Center for Translational Medicine KL2, $393,281; Toto, Robert, NIH, UTSW Center for Translational Medicine TL1, $110,253;

Towler, Dwight, NIH, Osteogenic Regulation of Vascular Calcification, $405,000; Vitetta, Ellen, Health Resch Inc/NIH, Development of an Assay to Predict Efficacy of Ricin Toxin Subunit Vaccines, $290,646; Wang, Jing, UT Arlington/NIH, Recovery of True Scatter in Blocked Regions for Blocker-Based Scatter Correction of CBCT, $8,748; Wolf, Matthias, NIH, Wolf-Renal Regulation, $81,000; Wright, Woodring, NIH, Gene Expression in Aging and Development, $354,369; Zhang, Chun-Li, NIH, In Vivo Reprogramming of Glial Fate for Spinal Cord Repair, $313,031; Zhu, Hao, NIH, Reactivation of Embryonic Growth Programs in Liver Cancer, $333,517.

Nonfederal Awards

Amatruda, James, Baylor Col of Med/CPRIT, The Adolescent and Childhood Cancer Epidemiology and Susceptibility Service, $324,489; Ariizumi, Kiyoshi, CPRIT, Targeting the DC-HIL Receptor for Anti-Cancer Immunotherapy, $389,922; Blount, Paul, Welch Fdn, Determining Protein Interactions for a Channel Involved in Mechanosensing, $80,000; Chopra, Rajiv, CPRIT, Recruitment of Rising Star, $416,053; Cowell, Lindsay, Univ of Kansas/PCORI, Greater Plains Collaborative Clinical Data Research Network Phase II, $159,169; Douglas, Peter, Welch Fdn, Stress-Mediated Actin Phosphorylation in Endocytosis and Intestinal Barrier Function, $65,000; Fox, Amanda, Fdn for Anesthesia Educ and Resch, Medical Student Fellowship 2017 Summer Program, $4,200;

Goldberg, Mark, UT System, Lone Star STroke Clinical Trial Network, $412,724; Horton, Jay, Fondation Leducq, Triglyceride Metabolism in Obesity & Cardiovascular Disease, $99,000; Hsiang, Michelle, Univ of Calif SF/Gates Fdn, UCSF Global Health Group Subcontract, $12,682; Iannaccone, Susan, Muscular Dystrophy Assn, MDA Care Center, $65,000; Jewell, Jenna, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Member, $500,001; Jiang, Jin, Welch Fdn, Biochemical Study of Hh Signaling at the Primary Cilium, $110,000; Jiang, Steve, CPRIT, Translating Online Adaptive Radiotherapy from Lab to Clinical Practice, $298,621; Jiang, Steve, CPRIT, Pediatric Radiation Oncology with Movie Induced Sedation Effect, $278,282; Joachimiak, Lukasz, Welch Fdn, Structural Basis for Chaperone Function in Polyglutamine Aggregation, $65,000; Kehoe, Siobhan, Women & Infants Hosp/PCORI, Cancer of the Uterus and Treatment of Urinary Incontinence, $23,465;

Lavery, Lawrence, Amer Diabetes Assn, Negative Pressure Wound Therapy as a Drug Delivery System, $199,968; Le, Lu Quang (Fellow C. Liao), Dermatology Fdn, Mechanisms Regulating Hair Pigmentation and Development, $55,000; Leavey, Patrick, CPRIT, Using Imaging and Computational Tools to Improve Risk Stratification in Children, $322,907; Levine, Beth, Washington Univ/Natl Inst of Infectious Dis, Autophagy Modulators as Novel Broad-Spectrum Anti-Infective Agents, $1,470,402; Li, Wen-Hong, Juvenile Diabetes Resch Fdn, Physiology of Beta Cell Functional Heterogeneity and Therapeutic Opportunity for T1D, $250,000; Medin, Paul, CPRIT, Peripheral Nerve Tolerance to Single-Session Stereotactic Irradiation, $299,382; Meeks, Julian, Welch Fdn, Identifying New Mammalian Bile Acid Receptors, $65,000;

Morrison, Sean (Fellow S. Geula), EGL Charitable Fdn, Deciphering the Mechanisms Regulating the Age of Hematopoietic Stem Cells, $80,848; Nam, Yunsun, Welch Fdn, Structure and Function of MicroRNA Precursors, $80,000; Phillips, Margaret, Welch Fdn, Purine Salvage Pathways as Potential Drug Targets in Trypanosomatid Parasites, $110,000; Powell, Craig, Baylor Col of Med/Autism Speaks, Identifying Biomarkers of GI Morbidity in ASD, $48,968; Reese, Michael, Welch Fdn, Unravelling the Non-Canonical Activation Mechanism of Toxoplasma Kinases, $65,000; Schmid, Sandra, CPRIT, Dynamin GTPase: Novel Pro-Apoptotic Cancer Therapeutic Target, $100,000;

Siegwart, Daniel, Welch Fdn, Design and Synthesis of Activatable pH-Responsive Water Soluble Dyes for Biomedical Imaging, $80,000; Srivastava, Divya, Amer Soc for Dermatologic Surg, Patient Satisfaction with Mohs Micrographic Surgery for Treatment of Melanoma in situ, $5,300; Trivedi, Madhukar, Massachusetts Genl Hosp/PCORI, Switching vs. Augmentation in Treatment Resistant Depression, $476,000; Wang, Sam, Soc for Surgery of Alimentary Tract, Identifying Genetic Biomarkers in Hispanic/Latino Gastric Cancer Patients, $20,000; Wu, Jiang, Welch Fdn, Tumor Suppression Function of Brg1/SMARCA4 is Disrupted by DCLK1-Mediated Phosphorylation, $65,000; Yancey, Kim (Fellow J. Gill), Dermatology Fdn, Transcriptional and Metabolic Adaptations Determining Melanoma Sites of Metastasis, $55,001; Yu, Hongtao, Welch Fdn, Biochemical and Structural Analysis of Cohesin and its Regulators, $110,000. 

Industry Sponsored Awards, dollar amounts not available

Ahmed, Tasneem, Hoffmann-La Roche, Study of Ulcerative Colitis Patients Previously Enrolled in Etrolizumab Phase 2/3 Studies; Bartolome, Sonja, Reata Pharma, Study of Bardoxolone Methyl for Pulmonary Hypertension; Collins, Robert, Beat AML, Biomarker-Based Treatment of AML; Gerber, David, Lineberger Cancer Center, Phase 2 Trial of Pembrolizumab; Greenberg, Benjamin, Medday Pharma, Effect of MD1003 in Progressive Multiple Sclerosis; Miller, David, Advaxis Inc, Phase 3 Study of ADXS11-001 for High Risk Locally Advanced Cervical Cancer; Murakami, Carol, Gilead Sciences, Phase 2 Study of GS-9674 for Nonalcoholic Steatohepatitis; Richardson, Debra, US Biotest, Phase 2 Study of Intraperitoneal NanoPac for Epithelial Ovarian Cancer Surgery; Tannin, Grace, Versartis Inc, Long-Term Study of Somavaratan in Children with Growth Hormone Deficiency.