Awards for August 2012

Federal Awards

Abrams, John, NIH, Molecular and Genetic Control of Programmed Cell Death, $346,221; Abrams, John, NIH, Molecular and Genetic Control of Programmed Cell Death - Diversity Supplement, $63,038; Adinoff, Bryon, UT Dallas/NIH, Genetic and Environmental Modulators of Brain’s Response to Marijuana Cues, $5,954; Ahn, Chul, Univ. of North Texas/NIH, Social Vigilance and Altherosclerotic Risk, $39,180; Amatruda, James, Univ. of Minn./NIH, Molecular Epidemiology of Pediatric Germ Cell Tumors, $11,277; Attanasio, Massimo, NIH, Role of GLIS2 in Development of Cystic Kidney Disease, $68,028; Bai, Xiaoying, NIH, Role of Transcriptional Intermediary Factor TIF1g in Vertebrate Hematopoiesis, $249,000; Banerjee, Subhash, Univ. of Toledo/NIH, CORAL – Cardiovascular Outcomes in Renal Atherosclerotic Lesions, $1,310; Barton, Theresa, HRSA, Ryan White Program; Dallas FAN, $1,100,000; Beutler, Bruce, NIH, Mutagenic Analysis of LPS Response, $813,237; Beutler, Bruce, NIH, Mutagenic Analysis of LPS Response, $51,789.

Blount, Paul, NIH, Molecular Mechanisms of Mechanosensitive Channel Gating, $333,900; Blount, Paul (J. Parker, Fellow), NIH, Functional Protein-Lipid Interactions for Mechanosensitive Channel MscS - Diversity Fellowship, $29,455; Brekken, Rolf (K. Aguilera, Fellow), NIH, SPARC as Regulator of Collagen Signaling in Pancreatic Cancer - Diversity Fellowship, $29,597; Burgess, Shawn, Duke Univ./NIH, Development of Novel Therapies for NIDDM: Project 3, $87,335; Cadeddu, Jeffrey, UT Arlington/NIH, Transrectal Imaging of Prostate Cancer Using Globally Convergent Method, $81,485; Cavanagh, Dwight, Jaeb Ctr. for Health Research/NIH, Cornea Donor Study, $400; Choi, Changho, NIH, In-Vivo Detection of 2-Hydroxyglutarate in Gliomas by Spectroscopic MRI, $207,495; Choy, Hak, American Coll. of Radiology/NIH, Radiation Therapy Oncology Group (RTOG) Committee Chair, $8,750; Cullum, Munro, UT Dallas/U.S. Dept. of Defense, Novel Treatment of Emotional Dysfunction in PTSD-Cullum, $88,783; Devous, Michael, UT Dallas/NIH, Neuroimaging of Dedifferentiation and Memory Across Lifespan, $18,037.

Dozmorov, Igor, Univ. of Florida/NIH, Characterization of SLE-Susceptibility Loci on Mouse Chromosome 1, $14,820; Drazner, Mark, Duke Univ./NIH, STICH – Surgical Treatment of Ischemic Heart Failure, $600; Fitzgerald, John, Duke Univ./NIH, IPFNET: Idiopathic Pulmonary Fibrosis Clinical Research Network – STEP and PANTHER Protocols, $6,106; Gattineni, Jyothsna, NIH, Fibroblast Growth Factor 23 (FGF23) and its Receptors, $145,195; Goldberg, Mark, NIH, Network of Excellence in Neuroscience Clinical Trials (NEXT), $318,000; Green, Carla, Univ. of Virginia/NIH, Analysis of New Circadian Mutant, $103,296; Gupta, Rana, NIH, FZfp423 in Control of Preadipocyte Determination, $137,629; Gupta, Roopali, HRSA, Teaching Interprofessional Learners an Individualized Approach for Geriatric Preventive Medicine, $77,691; Haller, Ronald, NIH, Exercise Adaptations in Mitochondrial Myopathy: Therapeutic Implications, $521,451; Hibbs, Ryan, NIH, 3-D Structure and Function of Neuronal Nicotinic Acetylcholine Receptors, $248,775.

Huang, Hao, NIH, Structural Development of Human Fetal Brain – U.S.-China Collaborative Supplement, $98,670; Huber, Kimberly, NIH, Mechanisms of mGluR Function and Dysfunction in Mouse Autism Models, $406,760; Johnson, Jane (M. Borromeo, Fellow), NIH, Functional Role of Ascll in Developing Spinal Cord, $29,420; Karandikar, Nitin (A. Tyler, Fellow), NIH, Immunotherapy Induced Regulation of Demyelinating Disease, $29,282; Kennard, Beth, UT Dalllas/NIH, Neuroimaging Biomarkers of Outcome for Diffuse Axonal Injury, $25,008; Khera, Amit, Univ. of Toledo/NIH, CORAL – Cardiovascular Outcomes in Renal Atherosclerotic Lesions, $1,040; Kohler, Jennifer, NIH, Metabolic Incorporation of Photocrosslinking Sugars to Study Sialoside Function, $307,751; Kohler, Jennifer, NIH, Metabolic Incorporation of Photocrosslinking Sugars to Study Sialoside Function - Diversity Supplement, $49,146; Kramer, Helmut, NIH, AMPylation, Novel Mechanism Regulating Visual Neurotransmission, $318,000.

Kraus, Lee, NIH, Activity of Nuclear Receptor Coregulators with Chromatin, $396,966; Kraus, Lee, NIH, Activity of Nuclear Receptor Coregulators with Chromatin - Diversity Supplement, $89,040; Lee, William, NIH, UT Southwestern: Clinical Site for Drug-Induced Liver Injury Network, $247,605; Levine, Benjamin, Univ. of Colorad/U.S. Dept. of Defense, Prediction of Acute Mountain Sickness Using Blood-Based Test, $79,036; Levine, Benjamin, NASA, Cardiac Atrophy and Diastolic Dysfunction During and After Long-Duration Spaceflight: Functional Consequences for Orthostatic Intolerance and Risk of Cardiac Arrhythmias, $50,818; Levine, Beth (C. He, Fellow), NIH, Novel Autophagy Gene Beclin 2 in Prevention of Type 2 Diabetes and Obesity, $90,000; Liu, Yi, NIH, Transcriptional and Post-transcriptional Regulation of Neurospora Circadian Clock, $337,875; Lu, Hanzhang, NIH, Vascular Physiology in Brain White Matter, $212,076; Lu, Hanzhang, UT Dallas/NIH, Neuroimaging of Dedifferentiation and Memory Across Lifespan, $19,356.

Luebke, Kevin, NIH, Ligands for Hairpin Precursor of MicroRNA Linked to Cancer and Heart Disease, $306,950; MacDonald, Raymond, Vanderbilt Univ./NIH, Genetic Control of Pancreatic Endocrine Cell Development, $51,551; MacDonald, Raymond, Vanderbilt Univ./NIH, Architecture and Communication Controlling the Efficient Generation of Beta Cells; VUMC37153, $39,625; McKnight, Steven (R. Halfman, Fellow), NIH, Contributions of Protein Aggregation to Gene Regulation and Phenotypic Diversity, $318,000; Minna, John, NIH, SPORE in Lung Cancer, $2,300,000; Morrison, Sean, NIH, Regulation of Stem Cell Aging, $298,661; Niederkorn, Jerry, NIH, Core Grant for Vision Research, $610,481; Olson, Eric (G. Huang, Fellow), NIH, Retinoic Acid Signaling in Heart Development and Regeneration, $124,554; Otwinowski, Zbyszek, Northwestern Univ./NIH, Center for Structural Genomics of Infectious Diseases, $79,867.

Pandita, Tej, Albert Einstein Coll. of Medicine/NIH, Rapid Development of Radioprotectors Using Anti-Apoptotic Approach, $75,000; Parada, Luis, NIH, Neurofibromatosis Research Center: From Animal Models to Therapeutics, $1,263,336; Patel, Vishal, NIH, Role of MicroRNA in Kidney Development and Pathogenesis of PKD, $145,555; Peng, Fangyu, NIH, Noninvasive Assessment of Traumatic Brain Injury with PET Using 64CuCl2, $208,295; Perez-Fontan, Julio, NIH, National Children’s Study Centers - Lamar County, $2,078,288; Phillips, Margaret, NIH, Targeting S-Adenosylmethionine Decarboxylase for HAT Drug Discovery, $838,349; Rege, Robert, UT Arlington/NIST, Quantitative Hyperspectral Imaging Visualizing Tissue Biochemistry During Clinic, $9,510; Rodriguez-Baez, Norberto, Johns Hopkins Univ./NIH, Effect of HBV DNA Methylation and Mutant 1762T/1764A on Viral Load and HCC, $223,828; Rosen, Michael (C. Pak, Fellow), NIH, Determining Structural Topology of Nephrin-Receptor-Signaling Complexes, $52,190.

Rosenberg, Roger, Columbia Univ./NIH, Epidemiology of Familial Late-Onset Alzheimer’s Disease, $56,000; Ross, Elliott, NIH, G Protein-Coupled Receptors - Structure and Regulation - Equipment Supplement, $31,800; Russell, David, Univ. of Calif. at San Diego/NIH, LIPID-MAPS, Sterol Core J, $486,085; Russell, David, Univ. of Calif at San Diego/NIH, LIPID-MAPS, Sterol Core J, $230,000; Sanchez, Pablo, Univ. of Alabama/NIH, Natural History of CMV-Related Hearing Loss and Feasibility of CMV Screening; CHIMES, $79,545; Sanchez, Pablo, Duke Univ./NIH, Fluconazole Prophylaxis for Prevention of Candidiasis in Infants <750 grams="" birth="" weight="" 1="" 000="" b="">Satterthwaite, Anne, NIH, Inhibitory Receptors in Early B Cell Development, $238,438; Scaglioni, Pier (K. Schuster, Fellow), NIH, Lung Cancer Initiating Cells in Tumor Mouse Model Deficient in Cdkn2ab, $57,734; Schiller, Joan, Easter Coop. Oncology Group/NIH, ECOG Clinical Trials - Federal Payments, $4,950; Schmid, Sandra, NIH, Mechanisms Regulating Clathrin-Mediated Endocytosis, $322,820; Schmid, Sandra, NIH, Defining the Role of Dynamin in Endocytosis, $307,166; Schmid, Sandra, NIH, Clathrin Coated Vesicle Cycle, $211,438.

Schwarz, Margaret, NIH, EMAP II: Pulmonary Vascular Mediator, $502,345; Self, David, Mount Sinai School of Medicine/NIH, Molecular Neurobiology of Drug Addiction, Pj 4, $266,000; Self, David (N. Buzin, Fellow), NIH, Role of TrkB Receptor and Its Signaling Pathways in Cocaine Reward and Addiction, $29,405; Shay, Jerry, NIH, Cancer Biology Training Grant, $321,872; Shay, Jerry (S. Wong, Fellow), U.S. Dept. of Defense, New Telomerase Inhibition Targets for Breast Cancer Therapy, $42,735; Skapek, Stephen, NIH, ARF Controls Vascular Regression During Eye Development, $381,586; Skinner, Celette, NIH, Parkland-UT Southwestern PROSPR Center: Colon Cancer Screening in Safety Net, $854,471; Snell, William, NIH, Gamete Membrane Adhesion and Fusion During Fertilization, $278,250; Sun, Xiankai, NIH, Noninvasive Assessment of Pancreatic Beta-Cell Mass, $361,777; Sun, Xiankai, U.S. Dept. of Defense, Molecular Innovations toward Theranostics of Aggressive Prostate Cancer, $118,457; Tamminga, Carol, Mount Sinai School of Medicine/NIH, Epigenetic Mechanisms of Depression, $158,792.

Timaran, Carlos, Univ. of Medicine & Dentistry of New Jersey/NIH, Carotid Revascularization Endarterectomy vs. Stent Trial (CREST), $17,450; Toto, Robert, Univ. of Utah/NIH, Systolic Blood Pressure Intervention Trial (SPRINT) - CKD Recruitment, $54,298; Trivedi, Madhukar, NIH, Clinical Trial Network: North Texas Node, $770,396; Tu, Benjamin, NIH, Metabolic Signals Driving Cell Growth and Proliferation, $314,820; Tu, Benjamin (S. Kaochar, Fellow), NIH, Temporal Dynamics of mRNP Granules in Relation to Cellular Metabolic State, $52,190; Vazquez, Miguel, NIH, Anatomic and Functional Predictors of Arteriovenous Fistula Maturation, $208,998; Wang, Junmei, NIH, Protein Design Using Physical Scoring Functions Integrated with Site Couplings, $198,750; Wang, Shusheng, NIH, Regulation of Ocular Angiogenesis by MicroRNAs, $357,750; Washington, Doris, NIH, Characterization of Regulatory T Cells Generated in DNA Abeta42 Immunized Mice, $79,479.

Willson, James, NIH, Cancer Center Support Grant - CTRP Data Registration Supplement, $74,981; Willson, James, NIH, Cancer Center Support Grant - Leadership Award Supplement, $47,638; Womack, Kyle, Univ. of Calif. at San Diego/NIH, ADNI-2: Alzheimer's Disease Neuroimaging Initiative 2, $51,025; Wu, Tianfu, Johns Hopkins Univ./NIH, Hopkins Lupus Cohort, $12,839; Zhang, Rong, NIH, Mild Cognitive Impairment: Cerebrovascular Dysfunction and Exercise Training (MPI), $865,598.

Non-Federal Awards

Bachoo, Robert, CPRIT, Novel MRI and MRS Methods for Imaging Cancer Metabolism: P02, $213,590; Brugarolas, James, CPRIT, Identification of a Novel Oncogene in Clear-Cell Renal Cell Carcinoma, $408,511; Buszczak, Michael, CPRIT, Improved Transgenesis Platform for Systematic Screening of Tumor Suppressor Activity in Complete Gene Families in Drosophila, $240,403; Cannon, Stephen, Muscular Dystrophy Assn., Disease Pathogenesis and Modification in Mouse Model of HypoPP, $132,749; Chen, Zhijian (X. Cai, Fellow), Howard Hughes Med. Inst., Regulation of MAVS in Antiviral Signaling, $43,000; Choe, Kevin, American Brain Tumor Assn., Genome-Wide Search for Mediators of Gliomag Initiation and Progression, $50,000; Choi, Changho, CPRIT, Novel MRI and MRS Methods for Imaging Cancer Metabolism: P04, $261,947; Corey, David (D. Dodd, Fellow), Life Sciences Research Fndtn., Mechanism of Promoter Targeted RNAs, $56,000.

Goldstein, Joseph (M. McFarlane, Fellow), Howard Hughes Medical Institute, Compensatory Appetite Stimulation in Ghrelin-Deficient Mice, $43,000; Graff, Jonathan (R. Ugrankar, Fellow), American Diabetes Assn., Characterization of Novel Genetic Factors of Hyperglycemia Identified in Drosophila Melanogaster through Partial Genome Screen, $42,750; Huber, Kimberly, Simons Fndtn., Mechanisms of Synapse Elimination by Autism-Linked Genes, $300,000; Le, Lu (A. Patel, Fellow), Children’s Tumor Fndtn., Epigenetic Mechanisms Underlie Malignant Peripheral Nerve Sheath Tumor Development, $32,000; Merritt, Matthew, CPRIT, Novel MRI and MRS Methods for Imaging Cancer Metabolism: P03, $216,603; Nijhawan, Deepak, Sass Fndtn. For Med. Research, Identifying Cancer Targets in Regions of Broad Genomic Celetion in Ovarian Cancer, $12,875.

Olson, Eric, Fondation Leducq, MiR-216a: Cell Death-Regulating microRNA During Myocardial Repair (P. da Costa Martins, Fellow), $150,015; Olson, Eric, Fondation Leducq, MiR-216a: Cell Death-Regulating MicroRNA During Myocardial Repair (P. da Costa Martins, Fellow), $150,015; Satterthwaite, Anne, Alliance for Lupus Research, Functional Relationships Between Lupus Susceptibility Loci Lyn and Ets1, $163,687; Sharifi, Nima, Howard Hughes Med. Inst., Ligand-Independent Expression of Androgen Responsive Genes, $75,000; Sherry, Dean, CPRIT, Novel MRI and MRS Methods for Imaging Cancer Metabolism: C01, $31,650; Wang, Richard, Burroughs Wellcome Fund, Akt-Mediated Regulation of Autophagy & Tumorigenesis through Formation of Beclin 1/Keratin Intermediate Filament Complex, $140,000; Zhu, Hao, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $223,600.

Industry Sponsored Awards, dollar amounts not available

Corey, David, Allele Selective Inhibition of Mutant Huntingtin by Single-Stranded Antisense Oligonucleotides (CHDI: A-5533); Haley, Barbara, Comparison of Chemo Plus Trastuzumab Plus Placebo vs. Chemo plus Trastuzumab Plus Pertuzumab as Adjuvant Therapy in Patients with Operable HER2-Positive Primary Breast Cancer; Husain, Mustafa, Trial of H1-Coil Deep Transcranial Magnetic Stimulation (TMS) in Conjunction with Mood Stabilizers in Subjects with Bipolar Depression; Jain, Raksha, Ph3 Study of Ivacaftor in Subjects with Cystic Fibrosis with R117H-CFTR Mutation; Journeycake, Janna, Dalteparin Sub-Analysis of Kids-DOTT Trial; Lavery, Lawrence, Ph3 Study of HP802-247 in Treatment of Venous Leg Ulcers; Miller, David, OVA1® Post Marketing Surveillance Study PS110001; Mohan, Chandra, Treatment of Murine Lupus and Anti-GBM Disease with BTK Inhibitor; Pride, Glenn, ACE: Aneurysm Coiling Efficiency Study of Penumbra Coil 400 System; Raskin, Philip, Ph2 Study of RM-131 Administered to Patients with Diabetic Gastroparesis.

Szmuk, Peter, Study of Oral Codeine Sulfate Administration in Pediatric Subjects 2-17 years with Post-Procedural Pain; Szmuk, Peter, Trial of Intravenous Ibuprofen in Pediatric Patients; Vega, Gloria, Adipocyte Cellularity in South Asians; Welch, Babu, Post Approval Registry, Elana Surgical Kit HUD; Winick, Naomi, Study of Dasatinib with Standard Chemotherapy in Pediatric Patients with Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia.