Research Awards - January 2012

Federal Awards

Alto, Neal, NIH, Bacterial Regulation of Eukaryotic Signaling Enzymes: Structure and Function, $301,496; Bezprozvanny, Ilya, NIH, Deranged Calcium Signaling and Polyglutamine Expansion Disorders, $33,656; Brown, E. Sherwood, NIH, Citicoline for Bipolar Disorder and Cocaine Dependence, $338,697; Brown, E. Sherwood, NIH, Attenuation of Corticosteroid-Induced Hippocampal Changes, $269,734; Brown, E. Sherwood, NIH, Reversing Corticosteroid-Induced Memory Impairment, $235,682; Byerly, Matthew, Duke Univ./NIH, Comparison of Long-Acting Injectable Medications for Schizophrenia, $83,961; Chen, Zhijian, NIH, Biochemical Dissection of RIG-I Antiviral Pathway, $396,771; Chook, Yuh Min, NIH, Structures and Mechanisms of Nuclear Import and Export, $276,976; Corey, David, NIH, Recognition of Chromosomal DNA by Chemically Modified Oligonucleotides, $295,442; Cowell, Lindsay, Duke Univ./NIH, Host Susceptibility S. Aureus, $19,708.

Elias, Carol, NIH, Neural Basis of Leptin Action on Reproduction, $329,234; Elliott, Jeffrey, NIH, Mechanisms of SOD1 Toxicity in ALS, $30,292; Farrar, John, NIH, Type 1 Interferon-Regulated T Helper Development, $353,523; Friedman, Deborah, Univ. of Rochester/NIH, Data Coordination and Biostatics Center for NORDIC Network, $12,344; Fullinwider, John, Houston Academy of Medicine/NIH, Dallas Community Partners Survey, $4,620; Gardner, Kevin, NIH, High Throughput Screen Development for Modulators of PAS/Coactivator Interactions (MPI) - Admin Supplement, $39,625; Gerber, David, Texas Tech Univ. Health Science Ctr./NIH, Phase I Trial Combining Fenretinide and Safingol to Target Overproduction, $65,638; Gimpel, Nora, Univ. Of North Texas Health Science Ctr./NIH, GoodNEWS (Genes, Nutrition, Exercise, Wellness and Spiritual Growth) Trial, $58,122; Greene, Robert, NIH, Glial Control of CNS State-Related Activity, $334,928.

Herz, Joachim, NIH, Metabolism of the VLDL Receptor and ApoE Receptor 2, $396,771; Klesse, Laura, Univ. of Alabama/U.S. Dept. of Defense, Neurofibromatosis Consortium (STARS - Protocol 101 Lovastatin), $82,550; Lavery, Lawrence, New York Univ. School Of Medicine/NIH, Wound EMR to Decrease Limb Amputations in Persons with Diabetes - ARRA Stimulus AHRQ, $190,859; Margraf, Linda, Natl. Childhood Cancer Fndtn./NIH, Cancer Therapy Evaluation Program; #021174, $3,456; Monteggia, Lisa, Mount Sinai School of Medicine/NIH, Neural Substrates of Appetitive Behavior in Mood and Motivation - Monteggia, $68,894; Okada, Pamela, Children’s Research Inst./NIH, Lorazepam for Treatment of Pediatric Status Epilepticus, $49,297; Parada, Luis, Mount Sinai School of Medicine/NIH, Neural Substrates of Appetitive Behavior in Mood and Motivation - Project II, $107,170; Patel, Ashish, Cedars-Sinai Med. Ctr./NIH, Role of GWAS Identified Variants as Predictors of Outcome to Anti-TNFa Therapy in Pediatric Inflammatory Bowel Disease, $4,725.

Paulk, M. Elizabeth, Dana-Farber Cancer Inst./NIH, Black-White Differences in Advanced Cancer Communication, Acceptance and Care, $86,669; Raskin, Philip, Case Western Reserve Univ./NIH, Epidemiology of Diabetes Interventions and Complications (EDIC), $269,600; Rogers, Zora, Baylor College Of Medicine/NIH, TCD with Transfusions Changing to Hydroxyurea (TWiTCH), $139,987; Ross, Theodora, NIH, Huntington Interacting Protein- 1(HIP1) and the Promotion of Neoplasia, $274,664; Rutherford, Cynthia, UT Health Science Ctr. at Houston/NIH, Region VI Comprehensive Hemophilia Program, $39,127; Shetgiri, Rashmi, NIH, Community-based Prevention of Youth Violence in Latinos, $126,626; Skapek, Stephen, NIH, TGF2-2 Controls p19Arf During Eye Development, $308,367; Sperandio, Vanessa, NIH, Quorum Sensing Regulation of EHEC Virulence Genes, $451,839; Suel, Gurol, Cornell Univ./NSF, CD1 Type 1: Distilling Freeform Natural Laws from Experimental Data - ARRA Stimulus Funding, $90,000.

Sweeney, John, Univ. of Chicago/NIH, ACE: Translational Studies of Insistence on Sameness in Autism, $272,663; Szmuk, Peter, Children’s Hospital Boston/U.S. Food and Drug Administration, GAS Study: Assessment of Long-Term Neurodevelopmental Outcomes in Pediatric Patients Administered Regional and General Anesthesia as Neonates or Infants, $1,332; Tamminga, Carol, NIH, Antipsychotic Influence on Altered MTL Neuronal Activity in Schizophrenia, $349,718; Tamminga, Carol, Beth Israel Deaconess Med. Ctr./NIH, Bipolar-Schizophrenia Consortium for Parsing Immediate Phenotypes, $32,000; Toto, Robert, Univ. Of Utah/NIH, Systolic Blood Pressure Intervention Trial (SPRINT) Clinical Center Networks (NHLBI) - ARRA Stimulus funding, $40,376; Toto, Robert, Univ. Of Utah/NIH, Pulse Wave Velocity and Central Aortic Pressure Outcome in SPRINT, $23,380; Westover, Arthur, NIH, Cardiovascular Risks of Prescription Amphetamine Use in National Veterans Study, $171,155; Zimmern, Philippe, New England Research Institutes/NIH, UITN Steering Committee, $84,523.

Non-Federal Awards

Babb, Tony (S. Lorenzo, Fellow), American Heart Assn. SW, Dyspnea Exertion in Obese Women: Effects of Exercise Training and Weight Loss, $40,000; Cadeddu, Jeffrey, UT Dallas/Texas Emerging Tech Fund, Future Semiconductor Commercialization (FUSION), $100,000; Chiang, Cheng-Ming, CPRIT, Arginine Methylation Link to HPV-16-Induced Cervical Cancer, $100,000; Chook, Yuh Min, CPRIT, Mechanisms of CRM1-Mediated Nuclear Export in Cancer, $263,157; Coppari, Roberto, American Heart Assn. Natl., Physiological Relevance of SIRT1 in Brain on Body Energy Metabolism, $77,000; DeMartino, George, CPRIT, Small Molecule Inhibitors of Proteasome Assembly: New Strategy for Cancer Therapy, $100,000; Elmquist, Joel (K. Kim, Fellow), American Heart Assn. SW, SF-1 in Ventromedial Hypothalamic Nucleus and Energy Homeostasis, $42,000; Galindo, Rene, Alex’s Lemonade Stand, Pediatric Sarcoma, Rhabdomyosarcoma and Mechanisms of Origin, $125,000; Gao, Jinming, CPRIT, Turn ON Tumor Contrast for Surgical Resection of Head and Neck Cancers, $321,752.

German, Dwight, Simons Fndtn., Identification of Candidate Serum Antibody Biomarkers for Autism Spectrum Disorders (ASD), $118,338; Haller, Ronald, Muscular Dystrophy Assn., Impaired Oxidative Capacity in McArdle Disease: Causes and Treatment, $127,700; Hofmann, Sandra, CPRIT, Protein Palmitoyltransferases as Novel Therapeutic Targets for Acquired Lung Cancer Vulnerabilities, $100,000; Iyengar, Puneeth, Natl. Lung Cancer Partnership, Inflammation and Lung Cancer Radiation Therapy Resistance thru Systemic Metabolic Dysregulation, $54,000; Janowski, Bethany, CPRIT, Regulation of Cyclooxygenase-2 (COX-2) Expression by Noncoding RNAs in Cancer, $210,526; Jiang, Qiu-Xing, CPRIT, Enabling Structure Determination of Functional Human Telomerase Holoenzyme, $225,824; McCulley, James, Research To Prevent Blindness, RPB Unrestricted Research Grant - 2012, $100,000; Mineo, Chieko, American Diabetes Assn., Role of Pentraxins and Endothelial Fegamma Receptor 11B in High-Fat Diet-Induced Insulin Resistance, $129,195.

Mirzaei, Hamid, CPRIT, Develop Cutting-Edge Proteomics Core Facility Based on High Resolution, High Accuracy Mass Spectrometry and High Throughput, Web-Based Bioinformatics Technology, $1,080,000; Nwariaku, Fiemu (K. Pozo, Fellow), NANETS, Identification of New RET-Associated Signaling Mechanisms in Medullary Thyroid Carcinoma (MTC), $50,000; Olson, Eric (M. Carrer, Fellow), American Heart Assn. SW, Role of microRNA 378 in Cardiac Metabolism and Hypertrophy, $25,000; Parada, Luis, CPRIT, Functional and Structural Characterization of Small Chemical Compounds that Arrest Glioma Stem Cell Growth with High Activity and Specificity, $499,955; Peltz, Matthias, American Heart Assn. SW, Influence of Metformin on Myocardial Substrate Metabolism and Function in Model of Ischemia and Cardioplegic Arrest, $70,000; Pfeiffer, Julie, American Cancer Society, Ribavirin Uptake as Determinant of HCV Treatment Response, $180,000; Rubin, Craig, Donald W. Reynolds Fndtn., Comprehensive Programs to Strengthen Physicians' Training in Geriatrics, $523,928.

Shay, Jerry (S. Singel, Fellow), Susan G. Komen For The Cure, Identify Key Genes in Breast Cancer Genome as Biomarkers of Chemosensitivity or Prognosis, $60,000; Siegelman, Mark, Crohn’s & Colitis Fndtn. Of America, CD44act Dependent Trafficking of Highly Potent Subset of Regulatory T Cells in Human IBD, $115,830; Sperandio, Vanessa, Burroughs Wellcome Fund, Interkingdom Signaling in Bacterial Pathogenesis, $80,000; Tu, Benjamin, Damon Runyon Cancer Research Fndtn., Novel Strategy for Attacking Tumors Based on Identification of Fundamental Carbon-Source Signal Driving Cell Growth, $150,000; Wang, Shusheng, Research To Prevent Blindness, Role of microRNA-23-27-24 Family Member in Age-Related Macular Degeneration, $62,500; Wright, Woodring, CPRIT, Validation of Factors of Telomerase Action (Assembly, Modification, Recruitment, Activation): Potential Targets for Telomerase Inhibition Therapy, $324,194.

Yan, Nan, Alliance For Lupus Research, Identification of Endogenous Nucleic Acids as Targets in Lupus, $177,120; Yu, Yonghao, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Members, $1,250,000; Zhang, Chun-Li, Whitehall Fndtn. Inc., Cellular Plasticity of Adult Brain, $75,000; Zigman, Jeffrey (D. Derderian, Fellow), American Heart Assn. SW, Role of Ventral Tegmental Area in Ghrelin’s Mediation of Eating Behaviors, $42,000.

Industry Sponsored Awards,
dollar amounts not available

Burner, James, Hospital Investigation of Serologic Testing and Results (HI-STAR) Study; Chang, Alice, Dose-Finding Study of Abiraterone Acetate in Adult Women with 21-Hydroxylase Deficiency; Corey, David, Allele Selective Inhibition of Mutant Huntingtin by Mismatch-Containing Duplex RNAs; Gerber, David, PhI Study of BMS-936558 in Combination with Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, or Carboplatin/Paclitaxel in Subjects with Treatment-Naive Stage IIIB/IV Non-small Cell Lung Cancer (NSCLC); Girod, Carlos, Ph3 Study of Pirfenidone in Patients w Idiopathic Pulmonary Fibrosis; Inrig, Jula, Bardoxolone Methyl Evaluation in Patients with Chronic Kidney Disease and Type 2 Diabetes: Occurrence of Renal Events (BEACON); Jain, Mamta, 240 mg BI 201335 Once Daily in combination with Pegylated Interferon alpha 2a and Ribavirin for Treatment of Chronic Hepatitis C (HCV) Genotype I Infection in HIV/HCV Co-Infected Patients; Jain, Mamta, Ph3 Study of TMC435 plus PegIFNa-2a (Pegasys) and Ribavirin (Copegus) Triple Therapy in Chronic Hep C Genotype-1 Sjbs with HIV Type 1.

Kenkel, Jeffrey, Fat Tissue Graft Viability and Survivability; Kershaw, Corey, Trial Eval Effect of Oral BIBF 1120, 150 mg 2x/Day, on Annual Forced Vital Capacity Decline, in Patients with Idiopathic Pulmonary Fibrosis (IPF); Lee, William, Study to Determine Safety and Pharmacokinetics of Ifetroban Injection in Hepatorenal Syndrome; Olson, Eric, Delivery Means of Anti-MiRs and MiR Mimics to Heart in Animal Models; O’Suilleabhain, Padraig, Carbidopa-Levodopa Extd-Release (CD-LD ER) Taken Alone/In Combination with Carbidopa-Levodopa Immediate Release (IR) to IPX066 Followed by Extensive Study of IPX066 in Subjects with Advanced Parkinson's Disease; Petroll, Walter, HRT III Rostock Corneal Module; Pride, Glenn, Feasibility Study of MicroVention Neurovascaular Self-Expanding Retrievable Stent System in Treatment of Wide-Necked Intracranial Artery Aneurysms; Raskin, Philip, Study of Pregabalin for Treatment of Subjects with Painful Diabetic Peripheral Neuropathy with Background Treatment of NSAID for Other Pain Conditions.

Rohrich, Rod, Scar Prevention and Clinical Effectiveness of Novel Mechanomodulating Polymer (REFINE study); Sawant, Amit, Development of Real-time Volumetric Monitoring Using Vision RT's AlignRT; Vusirikala, Madhuri, Ph3 Study of US-ATG-F Prophylaxis as Supplement to Standard Prophylaxis to Prevent Mod-Severe Chronic GVHD in Adult Acute Myeloid Leukemia, Acute Lymphoid Leukemia, and Myelodysplastic Syndrome Patients after Allogenic Stem Cell Transplantation from Unrelated Donors; Whitson, Jess, Three-Month Study with Planned Three-Month Safety Extension.

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