June Awards — September 2010

Federal Awards

Abrams, John, NIH, Genetics Training Program, $122,218; Amatruda, James, NIH, Generation and Rapid Mapping of Low-Penetrance Disease Alleles in Zebrafish, $325,775; Bharucha, Kamal, NIH, Neuro­endocrine Control of Energy Balance by Drosophila AKH/Glucagon Receptor, $143,640; Boothman, David, NIH, Ku70 Binding Protein-5 (KUB5), Novel Factor in Nonhomologous End Joining, $328,888; Brown, E. Sherwood, NIH, Antidepressant Treatment at Inner City Asthma Clinic, $431,665; Brown, Kathlynn (T. Diaz, fellow), NIH, Using Isolated Cell-Specific Peptides to Improve Cancer Immunotherapy, $28,697; Browning, Jeffrey, NIH, Non-Alcoholic Fatty Liver Disease, Eth­nicity and Hepatic Metabolism, $132,570; Butovich, Igor, NIH, Biochemistry and Biophysics of Preocular Tear Film - Equipment Supplemental, $131,106; Byerly, Matthew, Duke Univ./NIH, Comparison of Long-Acting Injectable Medications for Schiz­ophrenia, $82,909.

Byerly, Matthew, Univ. of North Carolina-Chapel Hill/NIH, CATIE: Metformin in Treatment of Anti­psychotic-Induced Weight Gain in Schizophrenia, $4,530; Caban, Mabel, NIH, Effects of Disability on Diagnosis of Breast Cancer, $124,200; Carroll, Thomas J., NIH, Role of Wnt Signaling in Kidney Tubule Formation, $310,860; Chan, Roger, NIH, Biome­chanical Characterization of Vocal Fold Tissues, $396,914; Chan, Roger, NIH, Biomechanical Charac­terization of Vocal Fold Tissues-Admin. Supple­mental, $116,361; Chiang, Cheng-Ming, NIH, E-2 Cellular Complexes in HPV Chromatin Tran­scription - ARRA Stimulus 2 Yr Resub, $282,894; Chuang, David, NIH, Inborn Errors of Metabolism in Cell Culture, $369,760; Cobb, Melanie, NIH, Cell & Molecular Biology Training Program, $399,547.

Crandall, Craig (M. Ganio, fellow), NIH, Thermo­regulatory Function in Euhydrated and Dehydrated Obese Individuals, $47,606; Crandall, Craig, NIH, Heat Stress and Circulatory Control, $288,123; Crandall, Craig, National Space Biomedical Research Inst., Temperature Regulatory and Cardio­vascular Responses to Exercise During Long Duration Space Flight, $25,000; DeBerardinis, Ralph, NIH, Metabolic Regulation in Growth-Factor-Dependent Cells, $133,920; Eisch, Amelia, NIH, Basic Science Training Program in Drug Abuse, $404,885; Eisch, Amelia, NIH, New Horizons in Adult Neurogenesis, $97,911.

Evans, Patricia, Wayne State Univ./NIH, Early Pharmacotherapy Guided by Biomarkers in Autism, $98,681; Fitzgerald, John, Duke Univ./NIH, Idiopathic Pulmonary Fibrosis Clinical Research Network: IPFNET, $19,321; Fontoura, Beatriz, NIH, Regulation of mRNA Export by Viral Proteins, $295,318; Fontoura, Beatriz, NIH, Regulation of mRNA Export by Viral Proteins-Diversity Supplemental, $37,857; Gardner, Kevin, NIH, Molecular Biophysics Predoctoral Train­ing Program, $122,082; Getachew, Yonas, NIH, Drug Induced Hepatotoxicity During Viral Hepatitis, $142,668.

Goldstein, Joseph, NIH, Molecular Basis of Cholesterol Metabolism, $5,439,491; Graff, Jonathan, NIH, Invertebrate Models of Fat Storage - ARRA Stimulus Equipment Supplemental, $100,000; Green, Carla, Northwestern Univ./NIH, Chemical and Genetic Manipulation of Circadian Systems-Project 4, $298,266; Greene, Robert, McLean Hosp./NIH, Glutamate Dysfunction and Schizophrenia, $171,141; Grishin, Nick, NIH, Computational Methods for Structural-Functional Studies of Proteins, $309,075; Halm, Ethan, Rutgers Univ./NIH, Self-Regulation and Self-Management in Older Asth­matics, $72,423; Henkemeyer, Mark, NIH, Bidirectional Tyrosine Kinase Signaling, $425,274; Horton, Jay, NIH, TORS 01: Taskforce for Obesity Research at UT South­western, $381,192; Huang, Jun-Shen, NIH, Ery­thro­poietin Receptor Signaling in Erythropoiesis, $392,500; Hughes, Carroll, NIH, Exercise Treatment for Depressed Youth, $210,640.

Hutchison, Michele, NIH, Effect on Murine Growth of BDNF Receptor and p38 Knockouts at Growth Plate, $79,250; Igarashi, Peter, NIH, UT Southwestern O'Brien Kidney Research Core Center, $860,168; Jeffrey, Frederick, Vanderbilt Univ. Med. Ctr./NIH, Integrated Imaging of Brain Function at 7 Telsa, $58,360; Johnson, Mark, Stanford Univ./NIH, Diffusion Weighted Imaging Evaluation for Understanding Stroke Evolution 2: DEFUSE - ARRA Stimulus Funding, $66,843; Johnson, Mark, Univ. of North Carolina-Chapel Hill/NIH, Carotid Occlusion Surgery Study (COSS), $425; Lee, William, NIH, Multicenter Group to Study Acute Liver Failure - ARRA Stimulus Admin. Supplemental, $425,660; Leitch, A. Marilyn, National Surgical Adjuvant Breast & Bowel/NIH, STAR P-2 Trial Service Agreement, $11,100; Leitch, A. Marilyn, Duke Univ./NIH, ACOSOG Admin Coordinating Ctr; Site 119, $2,000; Leveno, Kenneth, George Washington Univ./NIH, Eunice Kennedy Shriver NICHD-MEFU Clinical Center Agreement, $183,015.

Levine, Benjamin, NIH, Aging, Fitness & Failure: Mechanisms of Diastolic Dysfunction, $589,473; Levine, Benjamin, NIH, Aging, Fitness & Failure: Mechanisms of Diastolic Dysfunction - Stability Testing Supplemental, $13,349; Li, Wen-Hong, NIH, Photo-activatable Fluorophores and Techniques for Biological Imaging Applications, $271,661; Lingvay, Ildiko, NIH, Role of Pancreatic Triglycerides in Beta-Cell Dysfunction, $151,200; Liu, Yi, NIH, Post-transcriptional Regulation of Neurospora Circadian Clock, $326,403; Lu, Hanzhang, NIH, Normalized Functional MRI in Human Brain Disorders, $318,374; Mahendroo, Mala, NIH, Molecular Mechanisms of Parturition, $245,520; Mangelsdorf, David, Baylor College of Medicine/NIH, Nuclear Receptors and Coregulators in Health and Disease, $169,560; Margraf, Linda, National Childhood Cancer Fndtn./ NIH, Cancer Therapy Evaluation Program, $5,626.

Mason, Ralph, Tufts Univ./NIH, Fluorinated Cell Surfaces to Modulate Biological Function, $50,523; McClintock, Shawn, NIH, Translational Research Evaluating Neurocognitive Memory Processes (TREC-MP), $128,618; McClung, Colleen (E. Falcon, fellow), NIH, Circadian Genes and Their Role in Drug Addiction, $28,423; McKearin, Dennis, NIH, Germ Cell Differentiation in Drosophila, $349,718; McKnight, Steven, NIH, Discovery, Characterization and Pre­clinical Development of Pro-Neurogenic Drugs (MPI), $1,260,917; Miller, David, Washington Univ. in St. Louis/NIH, Methylation Markers for Prognosis in Endometrioid Endometrial Cancers, $18,706; Niederkorn, Jerry, NIH, Core Grant for Vision Research - ARRA Stimulus Other, $639,991; Niederkorn, Jerry, NIH, Transplant and Tumor Rejection Processes Within the Eye, $388,575; Niederkorn, Jerry, NIH, Transplant and Tumor Rejection Processes Within the Eye-Diversity Supplemental, $63,720; Norgard, Michael, NIH, Molecular Microbiology Training Grant, $255,712.

North, Carol, Washington Univ. in St. Louis/NIH, Multidisciplinary Evaluation of Chronic Pelvic Pain Syndrome, $12,296; Packer, Milton, NIH, North and Central Texas Clinical and Translational Science Initiative - K12 Mentored Career, $894,507; Packer, Milton, NIH, North and Central Texas Clinical and Translational Science Initiative - T32 PreDoc. Res. Training, $92,311; Pandita, Tej, NIH, Chromatin Modifying Factor Control Radiation Response and Genomic Stability, $13,487; Pandita, Tej, NIH, Chro­matin Structure and DNA Repair, $3,000; Punaro, Marilynn, Children's Hosp. & Regional Med. Ctr./NIH, Early Aggressive Therapy in Juvenile Idiopathic Arthritis - TREAT, $8,716; Repa, Joyce, NIH, TORS 08: TL1 Interdisciplinary Research Training Program, $108,086; Rice, Luke (E. Garza, fellow), National Science Fndtn., Understanding Microtubule Dynamics Using Biochemically Defined Tubulin Mutants, $40,500.

Rogers, Zora, New England Research Institutes/­NIH, Thalassemia Clinical Research Net­work -­ Oral Sildenafil Pilot, $531; Roth, Michael, NIH, Using Chemical Biology to Interfere With Influenza Virus Life Cycle, $419,125; Roth, Michael, NIH, Novel Inhibitors of Viral Replication (MPI), $419,125; Rothermel, Beverly, NIH, Calcineurin's Role in Circa­dian Regulation of Cardiac Function and Remodeling, $392,500; Sanchez, Pablo, Duke Univ./NIH, Multiple Dose Pharmacokinetic Study of Meropenem in Young Infants With Suspected or Complicated Intra-Abdominal Infections, $2,328; Schaffer, Joseph, NIH, NICHD Pelvic Floor Disorders Network, $233,223; Scherer, Philipp (K. Davis, fellow), NIH, Establishment of Adiponectin as PPARgamma Cofactor, $26,905; Scheuermann, Richard, Northrop Grumman Corp./NIH, Bioinformatics Resource Center for Biodefense and Emerging/Re-Emerging Infectious Diseases-Influenza Extension, $413,896.

Schiller, Joan, Univ. of Chicago/NIH, Cancer and Leukemia Group B (CALGB) Case Study Services, $50; Sherry, A. Dean, NIH, Metabolism in the Heart by NMR, $392,500; Souza, Rhonda, NIH, Role of Acid in Development of Barrett's Esophagus - ARRA Stimulus Admin. Supplemental, $43,563; Sternweis, Paul, NIH, Signal Transduction via Receptors and G Proteins - ARRA Stimulus Admin. Supplemental, $105,940; Story, Michael, UT Medical Branch at Galveston/NASA, NASA Specialized Center of Research on Radiation Carcinogenesis, $210,820; Tamminga, Carol, NIH, Basic Science Training Program in Neurobiology of Mental Illness, $192,417; Timaran, Carlos, Univ. of Medicine & Dentistry of N.J./NIH, Carotid Revascularization Endarterectomy vs. Stent Trial (CREST), $3,600; Trivedi, Jaya, Univ. of Kansas FDA, Phase II Therapeutic Trial of Mexiletine, $35,575; Weakley, David, Emory Univ./NIH, Infant Aphakia Treatment Study (IATS), $6,182.

Womack, Kyle, Univ. of California, San Diego/NIH, Alzheimer's Disease Neuroimaging Initiative Grand Opportunity (ADNI-GO) - ARRA Stimulus Funding, $10,000; Wu, Tianfu, NIH, Signaling Status in Lupus, $79,250; Xu, Che, NIH, Xenogenic Scaffolds for Repair of Acute Vocal Fold Lamina Propria Injury, $158,500; Yuan, Joseph, NIH, Gating Mechanism of TRPCs and Orai1 by STIM1 & Their Role in Cardiac Hypertrophy, $91,351; Zhang, Chengcheng, U.S. Dept. of Defense, Dissecting Role of IGFBP2 in Development of Acute Myeloid Leukemia, $392,500; Zhang, Chengcheng, NIH, Expansion of Hematopoietic Stem Cells by Angio­poietin-like 2, $164,160; Zinn, Andrew, NIH, Medical Scientist Training Program at UT Southwestern, $833,736.

Nonfederal Awards

Alto, Neal, Welch Fndtn., Structural and Biochemical Analysis of Bacterial Protein Mimicry, $50,000; Amatruda, James, Welch Fndtn., Chemical Genetic Approaches to Biology and Treatment of Childhood Cancers, $50,000; Argenbright, Keith, CPRIT, Breast Screening and Patient Navigation (BSPAN), $499,969; Attanasio, Massimo, American Society of Nephrology, Role of GLIS2 in Development of Cystic Kidney Disease, $100,000; Berry, Jarett, American Heart Assn. SW, Lifetime Risks for CVD: Importance of Physical Fitness, $70,000.

Blount, Paul, CPRIT, Imaging Cancerous Tissues With Liposomal MRI Contrast Agents That Utilize Bioengineered Nanovalves, $336,944; Blount, Paul, Welch Fndtn., Determining Lipid-Protein Interac­tions for Channel Gated by Membrane Tension, $50,000; Borrelli, Joseph (P. Chin, fellow), Orthopaedic Research and Education Fndtn., Effect of BMP-7 on Articular Cartilage Following an Impact Load, $10,000.

Bowers, Daniel, St. Jude Children's Research Hosp., Risk Adapted Therapy For Children Under 3 Yrs with Embryonal Brain Tumors, High-Grade Glioma, Choroid Plexus Carcinoma or Ependymoma, $6,875; Brown, Kathlynn, Welch Fndtn., Design and Synthesis of Tumor Targeted Drug Delivery Systems for Lung Cancer Therapy, $50,000; Brugarolas, James, CPRIT, Identification of a Novel Oncogene in Clear-Cell Renal Cell Carcinoma, $393,466; Burma, Sandeep, CPRIT, Impact of GBM-Specific Oncogenic Events on DNA Repair Pathways: Implications for Therapy, $279,196; Buszczak, Michael, CPRIT, Improved Trans­genesis Platform for Systematic Screening of Tumor Suppressor Activity in Complete Gene Families in Drosophila, $240,103; Castrillon, Diego, CPRIT, Model Systems and Translational Studies of Cervical Cancer Progression, $268,091; Castrillon, Diego, Texas Higher Education Coordinating Board, Role of Foxo1 in Tes­tic­ular Stem Cell Maintenance and Differ­entiation, $90,000.

Chen, Chuo, Welch Fndtn., Synthesis of Lanci­fodilactone F and Buxapentalactone, $50,000; Chen, David, CPRIT, DNA Double-Strand Break Repair and Its Impact on Genome Stability, $25,000; Chong, Benjamin, Dermatology Fndtn., Signaling Pathways of Cutaneous Lupus, $55,000; Chook, Yuh Min, Leukemia & Lymphoma Society, Mechanisms of CRM1-Mediated Nuclear Export in Leukemia, $110,000; Chook, Yuh Min, Welch Fndtn., Structural Basis for Substrate Specificity Overlap in Yeast Nuclear Import Pathways, $50,000; Cobb, Melanie, Welch Fndtn., Regulatory and Catalytic Properties of MAP Kinase Cascades, $90,000; Corey, David, Welch Fndtn., Recognition of Chromosomal DNA by Synthetic Oligomers, $90,000; Courtney, Ardith, Univ. of California, Los Angeles/National Multiple Sclerosis Society, Combination Trial of Copaxone and Estriol in Relapsing Remitting MS, $147,588.

De Brabander, Jef, Welch Fndtn., Novel Hetero­cyclizations for Natural Product Synthesis, $70,000; Deisenhofer, Johann, Welch Fndtn., Structural Studies on DNA Photolyases and Cryptochromes, $90,000; Drazner, Mark (J. Thibodeau, fellow), Medtronic Inc., Advanced HF/Transplant Fellow, $30,000; Fu, Qi (S. Jarvis, fellow), American Heart Assn. SW, Neural Control of Blood Pressure During Pregnancy: Racial Com­par­ison, $40,000; Gardner, Kevin, CPRIT, Discov­ery and Optimization of Natural and Artificial Lig­ands Regulating Hypoxia Inducible Factor, $510,420; Gardner, Kevin, Welch Fndtn., Comparative Studies of Signaling Mechanisms of Flavin-Based Protein Photo­sensors, $50,000; Garrard, William, Welch Fndtn., Formaldehyde Cross-Linking for Discovery of Novel Regulatory Elements Exhibiting Long-Range Inter­actions Within and Between Chromosomes, $50,000.

Goldsmith, Elizabeth, CPRIT, Mapping Inhibitor Interactions and Conformational Space of MAP3K TAO2, New Protein Kinase Cancer Drug Target, $239,753; Goldsmith, Elizabeth, Welch Fndtn., Struc­tural and Functional Insights Into Activation Mecha­nism of SR1/SPAK Kinase, $90,000; Graff, Jonathan (D. Zeve, fellow), American Heart Assn. SW, Response of White Adipose Progenitor Cells to Physiological Changes Caused by High Fat Diet and Exercise, $25,000; Graff, Jonathan (W. Tang, fellow), American Heart Assn. SW, Adipose Stem Cells in Adipose Development and Homeostasis, $42,000; Greenberg, Benjamin, Guthy-Jackson Charitable Fndtn., Guthy-Jackson Repository for NMO, $165,000; Gupta, Samir, CPRIT, Increasing Colorectal Cancer Screening in Safety-Net Health System With Focus on Uninsured: Benefits and Costs, $553,464; Hill, Joseph (Z. Wang, fellow), American Heart Assn. SW, Unfolded Protein Response: Role in Pathological Cardiac Remodeling, $42,000.

Hofmann, Sandra, Welch Fndtn., Regulation of Pro­tein Palmitoylation by PDZ Domain-Mediated Inter­actions, $50,000; Hsieh, Jenny, CPRIT, Small Molecule Differentiation Agent to Target Glioma Stem Cells, $195,681; Jiang, Jin, CPRIT, Dissecting Hippo Tumor Suppressor Pathway in Organ Size Control and Stem Cell Proliferation, $401,272; Jiang, Jin, Welch Fndtn., Biochemical Study of Ubiquitin Pathways in Cell Signaling, $50,000; Jiang, Qiu-Xing, Welch Fndtn., Structural Basis for Calcium Modulation of Inositol 1,4,5-Triphosphate Receptor, $50,000; Katafuchi, Takeshi, American Heart Assn. SW, CNP/GC-B system: New Adipogenesis Regulator, $70,000; Kliewer, Steven, Welch Fndtn., Role of FGF21 in Mediating Anti­diabetic Actions of Thiazolidinedione Drugs, $90,000; Kohler, Jennifer, Welch Fndtn., Photo-Sugar for O-GicNAc Interaction Discovery, $50,000; Kramer, Helmut, Texas Higher Education Coordinating Board, Systems Approach to Define a Novel Pathway Regulating Autophagy, $100,000.

Kuro-o, Makoto, Texas Higher Education Coordi­nating Board, Suppression of Aging and Chronic Kidney Disease by Reducing Intestinal Phosphate Absorption, $79,488; Le, Lu Quang, Dermatology Fndtn., Cell of Origin and Tumor Microenvironment in NF1-Associated Neurofibroma Genesis, $55,000; Li, Bing, Welch Fndtn., Biochemical Characterization of Binding of Rpd3S Histone Deacetylase Complex to Methylated Chromatin, $50,000; Li, Wen-Hong, CPRIT, Photonic Probes for Functional Analysis of microRNAs and mRNAs in Living Cells, $249,079; Liu, Qinghua, Welch Fndtn., Mechanistic Studies of Drosophila RNA Interference Pathway, $50,000; Liu, Yi, Welch Fndtn., Biochemical Analysis of RNA Inter­ference Pathway, $70,000; Liu, Zhi-Ping (M. Zhu, Fellow), American Heart Assn. SW, Role of FoxO4 in Remod­eling Process After Myocardial Infarction, $40,000.

Lu, Christopher (Y. Wang, fellow), Genzyme Corp., Tenascin C in Ischemic Acute Kidney Injury, $50,000; Luebke, Kevin, CPRIT, Suppressing Maturation of Onco­genic MicroRNA With Small Molecules, $418,820; Lum, Lawrence, CPRIT, Molecularly Targeted Anti-Cancer Therapeutic Strategy Premised Upon Attack of Aberrant Wnt Pathway Responses, $435,204; MacMillan, John, Texas Higher Education Coordinating Board, Enzyme Catalyzed Halogenation Reactions Using Marine Derived Bacteria, $99,430; MacMillan, John, Welch Fndtn., New Methodology for Determination of Absolute Stereochemistry in Poly­ketides, $50,000; Malloy, Craig, CPRIT, Texas A&M Univ.-UT Southwestern Partnership for Cancer Imaging and Spectroscopy at 7 Tesla, $531,320.

Mangelsdorf, David, CPRIT, Development of Nu­clear Receptor and Coregulator Profiles for Diagnostic and Therapeutic Targeting of Breast and Lung Cancers, $2,287,975; Mangelsdorf, David, Welch Fndtn., Ligand Binding Properties of Nematode Orphan Nuclear Receptors, $90,000; Mohan, Chandra (Y. Du, fellow), Arthritis Fndtn., Molecular Genetics of Glomerular Crescent Formation, $50,000; Norgard, Michael, Welch Fndtn., Biophysical Characterization of Novel Bacterial TRAP Transporter, $70,000; Olson, Eric (E. Small, fellow), American Heart Assn. Natl., Regulation of Post-MI Cardiac Remodeling and Fibrosis by MRTF-A, $77,000; Olson, Eric (M. Xin, Fellow), American Heart Assn. SW, Requirement of Yap and Taz for Cardiac Homeostasis, $69,999; Orth-Taussig, Kimberly, Welch Fndtn., Enzymatic and Structural Characterization of AMPylator, Vibrio VopS, $90,000; Ouyang, Zhiming, American Heart Assn. SW, Influence of BosR on RpoS Regulon and Virulence Expression in Borrelia Burgdor­feri, $70,000; Parada, Luis, CPRIT, Genetic Mouse Models of Glioma: Translational Tool for Therapeutic Development, $577,570.

Phillips, Margaret, Welch Fndtn., Structural Basis for Substrate Specificity in B/a-barrel Fold Decar­boxylases, $90,000; Ranganathan, Rama, Welch Fndtn., Principles of Allosteric Control in Proteins, $90,000; Ready, Joseph, CPRIT, Evaluating Therapeutic Potential of Potent Anti-Cancer Agent, $268,547; Ready, Joseph, CPRIT, Understanding Activity of Potent Anticancer Agent, $100,000; Ready, Joseph, Welch Fndtn., Synthesis and Application of Optically Active Allenes, $50,000; Rice, Luke, Welch Fndtn., Engineering aB-Tubulin to Dissect Molecular Mecha­nisms of Microtubule Assembly, $50,000; Rosen, Michael, Welch Fndtn., Genetically Encoded Photo­switchable Proteins: Tools to Understand Cell Migration and Signaling, $50,000; Ross, Elliott, Welch Fndtn., Coordinate Regulation of Phospholipase C-B by Gag and Gby, $50,000; Rothermel, Beverly (M. Iglewski, fellow), American Heart Assn. SW, Studying Mechanisms of Mitophagy in Heart Failure, $40,000.

Scott, Daniel, UT System, Improving Patient Safety and Healthcare Delivery Effectiveness by Ensuring Competency for Laparoscopic Surgery: FLS Training and Certification for UT Surgeons and OR Personnel, $85,560; Seidel, Michelle (S. Baek, fellow), American Heart Assn. SW, Role of Capsulin in Epicardial Cell Development, $25,000; Shay, Jerry, CPRIT, Apply Genomics and HTP Techs to Prevent/Treat Colon Cancer, $17,000; Sherry, A. Dean, CPRIT, Novel MRI and MRS Methods for Imaging Cancer Metabolism, $838,473; Sternweis, Paul, Welch Fndtn., Structure and Mechanism of Signaling Enzymes and Pathways, $50,000; Tiro, Jasmin, CPRIT, Intervention Promoting HPV Vaccination in Safety-Net Clinics, $198,599; Tu, Benjamin, Welch Fndtn., Functional Roles of Bio­logical Gases Hydrogen Sulfide and Carbon Monox­ide, $50,000; Uyeda, Kosaku, Welch Fndtn., Biochem­ical Mechanism of Glucose Sensing and Regulation of ChREBP Activity, $50,000.

Wan, Yihong, CPRIT, Osteoclast Regulation of Bone Metastasis of Cancer, $315,789; White, Michael (M. Potts, fellow), Susan G. Komen for the Cure, Geno­type-Specific MicroRNA Function in Breast Cancer, $60,000; White, Michael, CPRIT, Cancer Intervention and Prevention Discoveries Program, $960,526; Winkler, Wade, Welch Fndtn., New Methods for Purification and Analytical Detection of Ribo­switch Ligands, $50,000; Wu, Jiang, Welch Fndtn., Chro­matin Regulation of Neuronal Activity-Depend­ent Gene Expression, $50,000; Wu, Lani, CPRIT, Relating Drug Resistance and Tumor Microenvi­ronment to Cancer Cell Heterogeneity, $498,790; Wu, Lani, Welch Fndtn., Signal Processing by Neutrophil Chemotaxis Pathway, $50,000; Xing, Chao, American Heart Assn, Natl., Identifying Less Frequent Variants With Large Effect Sizes in Genome-Wide Scans, $77,000.

Yilmaz, Cuneyt, American Lung Assn., Structure-Function Relationships in Fatty Diabetic Lung, $40,000; Yin, Helen, Welch Fndtn., Regulation of Type II Phosphatidylinositol Kinase a by Oxidative Stress, $50,000; Yu, Hongtao, Welch Fndtn., Biochemical and Structural Analysis of Spindle Checkpoint, $50,000; Zhang, Chengcheng, CPRIT, Role of IGFBP2 in Acute Myeloid Leukemia, $399,083; Zhang, Chengcheng, Welch Fndtn., New Chemical Approaches to Study Hematopoietic Stem Cells, $50,000; Zhang, Chun-Li, Welch Fndtn., Biochemical Regulation of Orphan Nuclear Receptor TLX, $50,000; Zhang, Hong, American Heart Assn. SW, Regulation of Flavocoenzyme Homeostasis, $70,000; Zhang, Xuewu, American Heart Assn. SW, Study of Mechanism FARP2 Regulation by Plexin, $70,000; Zhang, Xuewu, Welch Fndtn., Studies of Autoinhibition Mechanisms for GTPase-Activating Protein Activity of Plexin B1, $50,000.

Industry-Sponsored Awards, dollar amounts not available

Carr, B., Phase 3, Randomized, Multicenter, Open-Label Study of Levonorgestrel-Releasing Intrauterine System (20 mcg/day) and Mirena for Long-Term, Reversible Contraception up to Five Years; Chin, K., Phase IV, Open-Label, Randomized, Multicenter Study of Safety, Tolerability, and Pharmacokinetics of ACT- 385781A Compared to Flolan in Injectable Prostanoid Treatment- Naïve Patients with Pulmonary Arterial Hypertension (PAH); Gerber, D., Preclinical Studies of In-bavituximab; Husain, M., Long-Term Follow-Up Study for Evaluation of Patients Who Have Deep Brain Stimulation System for Adjunctive Treatment of Major Depressive Disorder; Jain, M., Grace Participant Survey; Lee, W., Boceprevir and Peginterferon/Ribavirin for Treatment of Chronic Hepatitis C in Treatment-Naïve Subjects: Comparison of Erythropoietin Use Versus Ribavirin Dose Reduc­tion for Management of Anemia.

Markham, D., Multicenter, Randomized, Double-Blind, Parallel Group, Active-Controlled Study to Evaluate Efficacy and Safety of LCZ696 Compared to Enalapril on Morbidity and Mortality in Patients with Chronic Heart Failure and Reduced Ejection Fraction; Okada, P., Initiation of Chronic Asthma Care Regimens in Pediatric Emergency Dept.; Olsen, N., Randomized, Double-Blind, Placebo-Controlled, Multicenter, Two-Part, Dose Ranging and Confirmatory Study with Operationally Seamless Design, Evaluating Efficacy and Safety of SAR153191 on Top of Methotrexate (MTX) in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to MTX Therapy; Pistenmaa, D., Phase I/II Study of Adjuvant Prostate Irradiation and Ixabepilone for High Risk Prostate Cancer Post-Prostatectomy; Quigley, R., International Pediatric Peritoneal Dialysis Network (IPPN); Takahashi, M., Development and Use of Novel Imaging Equipment.

Torres, F., Long-Term Extension, Multicenter, Multinational Study to Evaluate Safety and Tolerability of Oral BAY 63-2521 (1 mg,  2 mg, or 2.5 mg tid) in Patients with Chronic Thromboembolic Pulmonary Hypertension (CTEPH), CHEST-2 Study.

September 2010