Research Awards: August 2010

Federal Awards

Abrams, John, NIH, Universal Determinants of Alcohol-Induced Toxicity, $349,718; Alto, Neal, NIH, Type III Effector Regulation of Host GTPase Signaling, $384,689; Altschuler, Steven, NIH, Turnkey Solution for Image Phenotype Classification, $310,860; Auchus, Richard, NIH, Activation of Androgen Biosynthesis and Drug Metabolism by Cytochrome b5 - ARRA Stimulus 2 Yr Resubmission, $345,400; Barton, Theresa, HRSA, Ryan White Program; Dallas FAN, $1,264,171.

Baum, Michel, NIH, Effect of Prenatal Programming on Renal Tubular Transport, $335,729; Brilakis, Emmanouil, NIH, Effect of Extended-Release Niacin on Saphenous Vein Graft Atherosclerosis, $312,400; Castrillon, Diego, NIH, Mentoring and Research in Mouse Models of Cancer and Infertility, $125,942; Castrillon, Diego, NIH, LKB1 Tumor Suppressor and Human Cancer, $829,961; Cavanagh, Harrison, Jaeb Ctr. for Health/NIH, Cornea Donor Study, $600.

Chen, David, NASA, Mechanisms of Repair of HZE Induced DNA Double-Strand Breaks in Human Cells, $326,460; Cleaver, Ondine, NIH, Endothelial Signals During Organogenesis - Diversity Supplemental, $61,953; Cowan, Christopher, NIH, Signaling Mechanisms of Retinal Axon Guidance - Diversity Supplemental, $58,245; De Brabander, Jef, NIH, Development of Small Molecule Orexin Receptor Agonists for Treating Narcolepsy - ARRA Stimulus Challenge Grant, $487,799; Dewey, Richard, NIH, Clinical Ctr. for Neuroprotection in Parkinson’s Disease - FS ZONE Supplemental, $42,600.

Diaz-Arrastia, Ramon, NIH, Phase II, Randomized Controlled Trial of Brain Tissue Oxygen Monitoring, $777,874; Eisch, Amelia (N. Decarolis, fellow), NIH, Stem Cells in Adult Hippocampus, $15,955; Elmquist, Joel (H. Lemko, fellow), NIH, Role of Ghrelin and NPY Signaling in the Regulation of Energy Homeostatis, $47,606; Falck, J. Russell, NIH, Novel Eicosanoids: Synthesis and Function, $407,684; Farrar, John (K. Hagan, fellow), NIH, Regulation of Memory CD4+ T Cell Responses by Type 1 Interferon - ARRA Stimulus Funding, $28,392.

Fitzgerald, John, Duke Univ./NIH, IPFNET: Idiopathic Pulmonary Fibrosis Clinical Research Network, $22,983; Freeman, Anne, CDC, Capacity-Building Assistance (CBA) to Improve Delivery and Effectiveness of HIV Prevention Services, $158,009; Glazer, Craig, Duke Univ./NIH, IPF-ACE: Anti-Coagulant Effectiveness in Idiopathic Pulmonary Fibrosis, $2,015; Gruchalla, Rebecca, Univ. of Wisconsin/NIH, Inner City Asthma Consortium (ICAC): Registry for Asthma Characterization and Recruitment (RACR) Supplemental, $26,105.

Hamra, Franklin, NIH, Biology of ErbB Gene Family in Spermatogonial Development - ARRA Stimulus 2 Yr Resubmission, $385,375; Hamra, Franklin, NIH, Molecular Mechanisms of Spermatogonial Development - ARRA Stimulus 2 Yr Resubmission, $325,775; He, Yu-Guang, Vital Art and Science Inc./NIH, Home-Based DR Vision Diagnostic System (SBIR), $15,524; He, Yu-Guang, Emmes Corp./NIH, Age-Related Eye Disease Study 2 (AREDS2), $7,695; Herz, Joachim, NIH, Enhancing Progranulin Expression - Therapy for Frontotemporal Dementia - ARRA Stimulus Challenge Grant, $499,999.

Hiesinger, P., NIH, Regulation of Synaptic Specificity in Visual System by Intracellular Trafficking, $388,575; Hill, Joseph, NIH, Training in Cardiovascular Research, $727,828; Hsieh, Jer-Tsong, UT Arlington/DOD, Temperature-Sensitive Polymer Magnetic Nanoparticles to Treat Prostate Cancer, $35,168; Huang, Chou-Long, NIH, Membrane Trafficking of Renal Potassium Channel, $323,684; Huang, Chou-Long (M. Wolf., fellow), Yale Univ./NIH, Pediatric Physician Scientist Program Award - Wolf, $17,054.

Husain, Mustafa, NIH, Validating New NIH Clinical Tools in Parkinson’s Disease With and Without Depression - ARRA Stimulus Challenge Grant, $489,146; Igarashi, Peter, NIH, MicroRNA-Based Therapeutics for Rare Cystic Kidney Diseases - ARRA Stimulus Challenge Grant, $486,109; Jain, Mamta, Fred Hutchinson Cancer Research Ctr./-NIH, FHCRC HVTN 505 Protocol Site Expansion, $324,025; Jiang, Youxing, NIH, Molecular Mechanisms of Cation Channel Selectivity, $267,878; Johnson, Jane, NIH, Genome Wide Identification of PTF1j Targets in Dorsal Neural Tube, $194,288.

Johnson, Mark, Univ. of North Carolina-Chapel Hill/NIH, Carotid Occlusion Surgery Study (COSS), $425; Joho, Rolf, NIH, Role of Kv3-type Potassium Channels in Alcohol Sensitivity - ARRA Stimulus Funding, $235,500; Karandikar, Nitin, NIH, Role of T Cells in Immune Modulation of Multiple Sclerosis - ARRA Stimulus Admin Supplemental, $297,188; Karandikar, Nitin,  NIH, Dissecting Immune Basis of Disease and Therapy - ARRA Stimulus Admin Supplemental, $50,000; Karp, David, NIH, High Throughput Screening of Autoimmune Epitome - ARRA Stimulus Challenge Grant, $485,635.

Kohler, Jennifer, NIH, Metabolic Incorporation of Photocrosslinking Sugars to Study Sialoside Function, $310,860; Kohler, Jennifer, National Science Foundation, Career: Genetic Method to Study Interactions Among Extracellular Proteins, $104,930; Kowalske, Karen, U.S. Dept. of Education, North Texas Burn Rehabilitation Model System (NTBRMS), $362,500; Kulkarni, Padmakar, NIH, Novel PET Imaging Agents for Early Diagnosis of Plaque Deposition in Alzheimer’s Disease - ARRA Stimulus Challenge Grant, $368,867.

Lavery, Lawrence, NIH, Instant Total Contact Cast to Heal Diabetic Foot Ulcers, $5,832; Lavery, Lawrence, NIH, Therapeutic Stockings to Prevent Foot Ulcers, $3,405; Lee, William, NIH, UT Southwestern: Clinical Site for Drug-Induced Liver Injury Network (DILIN); Site 106, $258,681; Levine, Beth, NIH, Beclin 1-Bcl-2 Interactions: Effects on Autophagy, $317,331; Lin, Fangming, NIH, Stem Cell Therapy for Acute Kidney Injury, $373,032; Lin, Fangming, NIH, Use of Umbilical Core Blood Derived HSC to Treat Acute Kidney Injury - ARRA Stimulus Challenge Grant, $307,249.

Livingston, Edward, NIH, TORS 10: Human Biology Core, $3,502; Lu, Hanzhang, NIH, Cognition and Cerebrovascular Function Across Lifespan, $198,025; MacMillan, John, NIH, Marine Actinomycetes as Resource for Anticancer Natural Products, $328,888; Malloy, Craig, NIH, Southwestern NMR Ctr. for In Vivo Metabolism, $1,045,790; Mangelsdorf, David, NIH, TORS 04: Role of FGF21 as Hormonal Mediator of PPARa Actions, $381,193.

Minna, John, NIH, SPORE in Lung Cancer, $2,300,000; Mohan, Chandra, NIH, Foreboding Lupus Nephritis in Minority Women, $512,915; Monteggia, Lisa, NIH, Antidepressants and Intracellular Signaling Linked to BDNF, $396,250; Niederkorn, Jerry, NIH, Immunobiology of Corneal Allografts, $349,718; Niederkorn, Jerry, NIH, Immunobiology of Corneal Allografts - Diversity Supplemental, $63,720; Niederkorn, Jerry, NIH, Core Grant for Vision Research - ARRA Stimulus Other, $58,500.

North, Carol, NIH, Psychoeducation for HCV and Alcohol Behaviors, $568,558; Nwariaku, Fiemu, NIH, Training in Trauma, Inflammation, Sepsis and Critical Care, $96,466; O’Suilleabhain, Padraig, Massachusetts General Hosp./NIH, Coenzyme Q10 in Huntington’s Disease, $3,240; Pandita, Tej, NIH, Tumor-Cell-Specific Targets for Combined Hyperthermia and Radiation Effects, $328,888; Parada, Luis, NIH, Neurofibromatosis Research Ctr.: From Animal Models to Therapeutics, $1,163,738.

Pasare, Chandrashekhar, NIH, Toll-Like Receptor Mediated Regulation of Effector and Memory CD4 T Cell Responses, $396,250; Patel, Vishal, NIH, Role of microRNA in Kidney Development and Pathogenesis of PKD, $145,555; Phillips, Margaret, NIH, Polyamine and Trypanothione Metabolism in Trypanosoma Brucei, $378,600; Powell, Craig, NIH, Novel Genetic Animal Models of Autism - ARRA Stimulus Autism Res, $274,750; Ranganathan, Rama, NIH, Mechanistic Analysis of Dynamic Scaffolding in Cellular Signaling Network, $349,718.

Repa, Joyce, NIH, TORS 08: RL9 Interdisciplinary Research Training Program, $134,010; Robertson, Danielle, NIH, P63/IGFBP3/BCL2 Control of Corneal Epithelial Homeostasis, $310,860; Rogers, Zora, CDC, Promoting Education and Outreach of Persons With Hereditary Blood Disorders: Identifying Patients w/DBA, $149,987; Roth, Michael, NIH, Concerted Attack on Patient Specific Oncogenic Vulnerabilities in Lung Cancer - ARRA Stimulus Grand Opps, $1,644,663; Russell, David, Univ. of California, San Diego/NIH, LIPID-MAPS, Sterol Core J, $515,040.

Scaglioni, Pier (K. Schuster, fellow), NIH, Lung Cancer Initiating Cells in Tumor Mouse Model Deficient in Cdkn2ab, $52,154; Schaffer, Joseph, Univ. of Michigan/NIH, Female Pelvic Floor Disorders - Data Coordinating Ctr., $40,147; Scherer, Philipp, NIH, Dissecting Adipose Depot-Selective Regulation of Gene Programs - ARRA Stimulus Challenge Grant, $500,000; Schiller, Joan, Eastern Coop Oncology Group Coordinating Ctr./NIH, ECOG Clinical Trials, $9,500; Shaul, Philip, NIH, CRP, eNOS and Endothelial Dysfunction - ARRA Stimulus 2 Yr Resubmission, $543,710.

Skinner, Celette, Indiana Univ. Medical Ctr./NIH, Promoting Colon Cancer Screening Among African-Americans, $13,927; Snell, William, NIH, Gamete Membrane Adhesion and Fusion During Fertilization, $272,003; Suel, Gurol, NIH, Regulation of Pluripotent Differentiation by Gene Circuit Interactions, $271,359; Taussig, Ronald, NIH, Mechanism of Drug-Induced Adenylyl Cyclase Super-Sensitization - ARRA Stimulus 2 Yr Resub, $274,750; Thiele, Dwain, NIH, CTL Effector Mechanisms in Adenoviral Hepatitis - Admin Supplemental, $46,751.

Thorpe, Philip, NIH, Broad Spectrum Treatment of Hemorrhagic Arenaviruses - ARRA Stimulus 2 Yr Resub, $383,917; Trivedi, Madhukar, NIH, Clinical Trial Network: North Texas Node, $835,558; Van Oers, Nicolai, NIH, MicroRNA Profiling of Pediatric Immunodeficiency Patients, $194,288; Vazquez, Miguel, NIH, Anatomic and Functional Predictors of Arteriovenous Fistula Maturation, $327,370; Vitetta, Ellen, NIH, Novel Vaccine to Prevent HCV Infection and Hence Liver Cancer - ARRA Stimulus Grand Opps, $620,020.

Vusirikala, Madhuri, National Marrow Donor Program/NIH, RDSafe: Multicenter Study of Hematopoietic Stem Cell Donor Safety and Quality of Life, $500; Ward Ober, Sally, NIH, Mechanistic Studies of FcRn Inhibitors for Treatment of IgG-Mediated Diseases - Consortium Supplemental, $169,825; White, Michael, NIH, Molecular Components Specifying Mucosal Cell Sensitivity to Influenza Infection - ARRA Stimulus Funding, $235,500; Willson, James, NIH, Cancer Ctr. Support Grant, $1,500,000; Winick, Naomi, National Childhood Cancer Fndtn./NIH, COG Chair Grant; Patient Capitation, $59,010.

Womack, Kyle, NIH, Radiological Biomarkers for Frontotemporal Lobar Degeneration, $123,725; Womack, Kyle, Univ. of California, San Diego/NIH, Alzheimer’s Disease Neuroimaging Initiative Grand Opportunity (ADNI-GO) - ARRA Stimulus Funding, $1,250; Wu, Lani, NIH, Image Based Phenotypic Profiling of Single-Cell Responses to Perturbations, $345,483; Xiao, Guanghua, NIH, Secondary Data Analyses for Substance Abuse Research, $296,259; Xie, Yang, NIH, Predicting Adjuvant Chemotherapy Response in Lung Cancer, $151,882.

Yanagisawa, Hiromi, NIH, Protease Regulation and Integrity of Connective Tissues of Pelvic Floor, $328,888; Zhang, Rong, NIH, Mild Cognitive Impairment: Cerebrovascular Dysfunction and Exercise Training (MPI), $482,979; Zigman, Jeffrey, NIH, Identification of Central Targets of Ghrelin, $125,358; Zimmerman, Matthew, Houston Academy of Medicine/NIH, Dallas Medical History, 1890-1975: Digital Collection, $25,000; Zinn, Andrew, Thomas Jefferson Univ./NIH, Androgen Effects on Klinefelter Syndrome Motor Function, $15,017. 

Nonfederal Awards

Bachoo, Robert, CPRIT, Novel MRI and MRS Methods for Imaging Cancer Metabolism, $213,521; Brekken, Rolf, American Cancer Society, Fibulin-5 as Regulator of Tumor Angiogenesis, $180,000; Burstein, Ezra, Crohn’s & Colitis Fndtn. of America, COMMD Proteins and Regulation of Inflammation in IBD, $128,700; Choi, Changho, CPRIT, Novel MRI and MRS Methods for Imaging Cancer Metabolism, $262,028; Comerford, Sarah, UT San Antonio/CPRIT, Genetics and Biology of Liver Tumorigenesis in Children, $70,000.

Drake, Robert, Texas Dept. of Assistance & Rehabilitation Services, DARS/DRS Community Rehabilitation Program (CRP), $264,263; Joglar, Jose (R. Williams, fellow), Medtronic Fellowship Funding - 2010-2011; Kittler, Ralf, CPRIT, Development of Nuclear Receptor and Coregulator Profiles for Diagnostic and Therapeutic Targeting of Breast and Lung Cancers, $250,000; Mangelsdorf, David, CPRIT, Development of Nuclear Receptor and Coregulator Profiles for Diagnostic and Therapeutic Targeting of Breast and Lung Cancers, $54,146; Merritt, Matthew, CPRIT, Novel MRI and MRS Methods for Imaging Cancer Metabolism, $208,866.

Minna, John, CPRIT, Development of Nuclear Receptor and Coregulator Profiles for Diagnostic and Therapeutic Targeting of Breast and Lung Cancers, $809,012; Rakheja, Dinesh, UT San Antonio/CPRIT, Genetics and Biology of Liver Tumorigenesis in Children, $94,996; Scaglioni, Pier (A. Rabellino, fellow), American Italian Cancer Fndtn., Identification of Signaling Networks Regulating Oncogene Induced Replicative Senescence in Non-Small-Cell Lung Cancer, $35,000; Sharifi, Nima, Howard Hughes Medical Inst, Ligand-Independent Expression of Androgen Responsive Genes, $75,000; Sperandio, Vanessa, Burroughs Wellcome Fund, Interkingdom Signaling in Bacterial Pathogenesis, $1,000. 

Industry-Sponsored Awards, dollar amounts not available

Anderson, Larry, Phase II, Multi-Ctr., Non-Random, Open-Label Study of TKI258 in Patients With Relapsed or Refractory Multiple Myeloma With or Without T(4;14) Translocation; Arko, Frank, Multi-Ctr. Random Cont Trial of Endovascular Aneurysm Repair Using Bilateral Percutaneous Approach (PEVAR) vs. Stand Approach (SEVAR) Using IntuiTrak Endovascular AAA Delivery and Prostar XL or Perclose ProGlide Suture-Mediated Closure System; Emslie, Graham, Double-Blind Efficacy and Safety Study of Duloxetine Versus Placebo in Treatment of Children and Adolescents With Major Depressive Disorder.

Harker-Murray, Paul, Open-Label Study of Bendamustine Hydrochloride for Treatment of Pediatric Patients With Relapsed or Refractory Acute Leukemia; Inrig, Jula, Effect of Doxercalciferol on Endothelial Cell Function in End Stage Renal Disease and Chronic Kidney Disease Stage IV and V; Punaro, Marilynn, Follow Up of Subjects From Trial of Early Aggressive Therapy of Juvenile Idiopathic Arthritis (TREAT in JIA).

Sulistio, Melanie, SAVOR-TIMI 53 – Multi-Ctr. Random Double-Blind Placebo-Controlled Phase IV Trial to Evaluate Saxagliptin on Cardiovascular Death, Myocardial Infarction or Ischaemic Stroke in Patients With Type 2 Diabetes; Timmerman, Robert, Phase I Study of Accelerated Hypofractionated Image-Guided Radiation Therapy (IGRT) in Patients with Stage II-IV Non-Small-Cell Lung Cancer and Poor Performance Status; Verma, Udit, Randomized Phase III Double-Blind Placebo-Controlled Multicenter Study to Evaluate Efficacy and Safety of Everolimus (RAD001) in Adult Patients With Advanced Hepatocellular Carcinoma After Failure of Sorafenib Treatment (EVOLVE-1).

 / October-November 2010