Publications

Publications for Nan Yan, Ph.D.

Featured Publications Legend

Featured Publications

Trafficking-Mediated STING Degradation Requires Sorting to Acidified Endolysosomes and Can Be Targeted to Enhance Anti-tumor Response.

Gonugunta VK, Sakai T, Pokatayev V, Yang K, Wu J, Dobbs N, Yan N Cell Rep 2017 Dec 21 11 3234-3242

Innate Immune Activation by cGMP-AMP Nanoparticles Leads to Potent and Long-Acting Antiretroviral Response against HIV-1.

Aroh C, Wang Z, Dobbs N, Luo M, Chen Z, Gao J, Yan N J. Immunol. 2017 Oct

STING-associated vasculopathy develops independently of IRF3 in mice.

Warner JD, Irizarry-Caro RA, Bennion BG, Ai TL, Smith AM, Miner CA, Sakai T, Gonugunta VK, Wu J, Platt DJ, Yan N, Miner JJ J. Exp. Med. 2017 Sep

Immune Diseases Associated with TREX1 and STING Dysfunction.

Yan N J. Interferon Cytokine Res. 2017 May 37 5 198-206

Mitotic Phosphorylation of TREX1 C Terminus Disrupts TREX1 Regulation of the Oligosaccharyltransferase Complex.

Kucej M, Fermaintt CS, Yang K, Irizarry-Caro RA, Yan N Cell Rep 2017 Mar 18 11 2600-2607

DNase-active TREX1 frame-shift mutants induce serologic autoimmunity in mice.

Sakai T, Miyazaki T, Shin DM, Kim YS, Qi CF, Fariss R, Munasinghe J, Wang H, Kovalchuk AL, Kothari PH, Fermaintt CS, Atkinson JP, Perrino FW, Yan N, Morse HC J. Autoimmun. 2017 Mar

Chronic innate immune activation of TBK1 suppresses mTORC1 activity and dysregulates cellular metabolism.

Hasan M, Gonugunta VK, Dobbs N, Ali A, Palchik G, Calvaruso MA, DeBerardinis RJ, Yan N Proc. Natl. Acad. Sci. U.S.A. 2017 Jan

Methods of Assessing STING Activation and Trafficking.

Pokatayev V, Yan N Methods Mol. Biol. 2017 1656 167-174

RNase H2 catalytic core Aicardi-Goutières syndrome-related mutant invokes cGAS-STING innate immune-sensing pathway in mice.

Pokatayev V, Hasin N, Chon H, Cerritelli SM, Sakhuja K, Ward JM, Morris HD, Yan N, Crouch RJ J. Exp. Med. 2016 Feb

Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice.

Hasan M, Dobbs N, Khan S, White MA, Wakeland EK, Li QZ, Yan N J. Immunol. 2015 Oct

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