Publications for Ken Westover, M.D., Ph.D.

Featured Publications Legend

Featured Publications

In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C.

Hunter JC, Gurbani D, Ficarro SB, Carrasco MA, Lim SM, Choi HG, Xie T, Marto JA, Chen Z, Gray NS, Westover KD Proc. Natl. Acad. Sci. U.S.A. 2014 Jun 111 24 8895-900

Radiation therapy as a backbone of treatment of locally advanced non-small cell lung cancer.

Laine AM, Westover KD, Choy H Semin. Oncol. 2014 Feb 41 1 57-68

Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM and ATR.

Liu Q, Xu C, Kirubakaran S, Zhang X, Hur W, Liu Y, Kwiatkowski NP, Wang J, Westover KD, Gao P, Ercan D, Niepel M, Thoreen CC, Kang SA, Patricelli MP, Wang Y, Tupper T, Altabef A, Kawamura H, Held KD, Chou DM, Elledge SJ, Janne PA, Wong KK, Sabatini DM, Gray NS Cancer Res. 2013 Feb

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

Taipale M, Krykbaeva I, Koeva M, Kayatekin C, Westover KD, Karras GI, Lindquist S Cell 2012 Aug 150 5 987-1001

Proton SBRT for medically inoperable stage I NSCLC.

Westover KD, Seco J, Adams JA, Lanuti M, Choi NC, Engelsman M, Willers H J Thorac Oncol 2012 Jun 7 6 1021-5

Treatment of non-small cell lung cancer patients with proton beam-based stereotactic body radiotherapy: dosimetric comparison with photon plans highlights importance of range uncertainty.

Seco J, Panahandeh HR, Westover K, Adams J, Willers H Int. J. Radiat. Oncol. Biol. Phys. 2012 May 83 1 354-61

Radical prostatectomy vs radiation therapy and androgen-suppression therapy in high-risk prostate cancer.

Westover K, Chen MH, Moul J, Robertson C, Polascik T, Dosoretz D, Katin M, Salenius S, D'Amico AV BJU international 2012 Apr

Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics.

Liu Q, Kirubakaran S, Hur W, Niepel M, Westover K, Thoreen CC, Wang J, Ni J, Patricelli MP, Vogel K, Riddle S, Waller DL, Traynor R, Sanda T, Zhao Z, Kang SA, Zhao J, Look AT, Sorger PK, Sabatini DM, Gray NS J. Biol. Chem. 2012 Mar 287 13 9742-52

Should a sentinel node biopsy be performed in patients with high-risk breast cancer?

Westover KD, Westover MB, Winer EP, Richardson AL, Iglehart JD, Punglia RS Int J Breast Cancer 2011 2011 973245

Significance testing as perverse probabilistic reasoning.

Westover MB, Westover KD, Bianchi MT BMC Med 2011 9 20

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