Motion management in radiation therapy

Respiration-induced tumor motion causes uncertainties and challenges when radiation is used to treat tumors in thoracic or upper abdominal regions. We are interested in developing novel strategies to manage tumor motion in radiation therapy. One of our recent research interests is on the development of high-quality four dimensional cone-beam CT (4D-CBCT). We developed a new 4D image reconstruction strategy that can perform simultaneous motion estimation and image reconstruction (SMEIR).

  • J. Wang, and X. Gu, "High quality four dimensional cone-beam CT by deforming prior images," Physics in Medicine and Biology, vol. 58, pp. 231-246, 2013.
  • J. Wang and X. Gu, "Simultaneous motion estimation and image reconstruction (SMEIR) for 4D cone-beam CT", Medical Physics, vol. 40, pp. 101912, 2013
  • J. Dang, X. Gu , T. Pan and J. Wang, "A pilot clinical evaluation of a 4D-CBCT scheme based on Simultaneous Motion Estimation and Image Reconstruction", Int J Radiat Oncol Biol Phys, vol. 91, pp. 410-418, 2015