Publications

Publications

Sperandio, V., Torres, A.G., Jarvis, B., Nataro, J.P. and Kaper, J.B. 2003. Bacteria-host communication: the language of hormones. PNAS. 100: 8951-8956.

 Clarke, M.B, Hughes, D.T., Zhu C., Boedeker, E.C. and Sperandio, V2006. The QseC sensor kinase: a bacterial adrenergic receptor. PNAS. 103: 19420-10425.

 Rasko, D.A., Moreira, C.G., Li, D.R., Reading, N.C., Ritchie, J.M., Waldor, M.K., Williams, N., Taussig, R., Wei, S., Roth, M., Hughes, D.T., Huntley, J.F., Fina, M.W., Falck, J.R., Sperandio, V. 2008. Targeting QseC Signaling and Virulence for Antibiotic Development. Science 321: 1078-1080.

 Reading, N.C., Rasko, R.A., Torres, A.T., and Sperandio, V. 2009. The two-component system QseEF and the membrane protein QseG link adrenergic and stress sensing to bacterial pathogenesis. PNAS 106(14):5889-94.

 Moreira, C.G., Weinshenker, D. and Sperandio, V. 2010. QseC mediates Salmonella enterica serovar Typhimurium virulence in vitro and in vivo. Infect. Immun. 78:914-26.

 Clarke, M.B. and Sperandio, V2005. Transcriptional regulation of flhDCby QseBC and σ28 (FliA) in EHEC. Mol. Microbiol. 57: 1734-1749.

Clarke, M.B., and Sperandio V. 2005.Transcriptional autoregulation by quorum sensing E. coli regulators B and C (QseBC) in enterohemorrhagic E. coli (EHEC). Mol. Microbiol. 58: 441-455.

Walters, M. and Sperandio, V. 2006. AI-3/epinephrine signaling in the kinetics of LEE gene expression in EHEC. Infect. Immun. 74: 5445-5455.

Reading, N.C., Torres, A.T., Kendall, M.M., Hughes, D.T., Yamamoto, K., and Sperandio, V2007. A novel two-component system that activates transcription of an enterohemorrhagic E. coli (EHEC) effector involved in remodeling of host actin. J. Bacteriol. 189: 2468-76.

Hughes, D.T, and Sperandio, V. 2008. Inter-kingdom signaling: communication between bacteria and host. Nature Reviews Microbiology. 6:111-20.

Hughes, D.T., Clarke, M.B., Yamamoto, K., Rasko, D.A., and Sperandio, V. 2009. The QseC adrenergic signaling cascade in enterohemorrhagic E. coli (EHEC). PLoS Pathogens 5:e1000553.

Sperandio, V2009. Deciphering bacterial language. Nature Chemical Biology. 5(12) 870.

Hughes, D.T., Terekhova, D.A., Liou, L., Hovde, C.J., Sahl, J. , Patankar, A.V., Gonzalez, J.E., Edrington, T.S., Rasko, D.A., and Sperandio, V. 2010. Chemical sensing in mammalian host-bacterial commensal associations. PNAS 2107:9831-6.

Rasko, D.A., and Sperandio, V. 2010. Anti-virulence strategies to combat bacteria-mediated disease. Nature Drug Review. 9:117-128.