The Schneider Lab is a part of the Department of Internal Medicine, Division of Cardiology, at UT Southwestern Medical Center in Dallas, Texas.
Our focus is a chemical biology and biomaterials approach to heart repair. In addition to cardiogenic small-molecules that target native progenitors in the injured heart, we study the biology of very large molecules like alginate, a Norwegian brown seaweed-derived polysaccharide biopolymer that functions as a tissue surrogate-scaffold when implanted as a hydrogel foreign body in the myocardium.
The biomechanical repair process, called “seaweed myocardial reGELeration,” is already in clinical trials. Complementing our cardiac studies, we have parallel interests in neurogenesis and brain repair.
Finally, as members of the NHLBI Progenitor Cell Biology Consortium and the University of Texas Southwestern Center for Regenerative Science and Medicine (CRSM), a major focus is the production, growth, differentiation, and therapeutic application of human pluripotent stem cells and their progeny.