Publications

Publications

Chen P.H., Bendris N., Hsiao Y.J., Reis C.R., Mettlen M., Chen H.Y., Yu S.L. and Schmid. 2017 Crosstalk between CLCb/Dyn1-Mediated Adaptive Clathrin-Mediated Endocytosis and Epidermal Growth Factor Receptor Signaling Increases Metastasis. Dev. Cell.

Reis C.R., Chen P.H., Bendris N. and S.L. Schmid. 2017 TRAIL-death receptor endocytosis and apoptosis are selectively regulated by dynamin-1 activation. PNAS.

Kadlecova Z., Spielman S.J., Loerke D., Mohanakrishnan A., Reed D.K. and S.L. Schmid. 2017 Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2. J. Cell Biol.

Bendris N and S.L. Schmid. 2017 Endocytosis, Metastasis and Beyond: Multiple Facets of SNX9. Trends Cell Biol.

Elkin S.R., Oswald N.W., Reed D.K., Mettlen M., McMillan J.B., and S.L. Schmid. 2016 Ikarugamycin: a natural product inhibitor of clathrin-mediated endocytosis. Traffic.

Bendris N., Stearns C.J., Reis C.R., Rodriguez-Canales J., Liu H., Witkiewicz A.W., and S.L. Schmid. 2016 Sorting nexin 9 negatively regulates invadopodia formation and function in cancer cells. J. Cell Sci.

Bendris N., Williams K.C., Reis C.R., Welf E.S., Chen P.H., Lemmers B., Hahne M., Leong H.S., and S.L. Schmid. 2016 SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of RhoGTPases. Mol. Biol. Cell.

Srinivasan S., Dharmarajan V., Reed D.K., Griffin P.R., and S.L. Schmid. 2016 Identification and function of conformational dynamics in the multidomain GTPase dynamin. EMBO J.

Elkin S.R., Bendris N., Reis C.R., Zhou Y., Xie Y., Huffman K.E., Minna J.D., and S.L. Schmid. 2015. A systematic analysis reveals heterogeneous changes in the endocytic activities of cancer cells Cancer Res,  75: 4640-50

Reis, C.R.,Chen, P.-H., Mettlen, M., Aguet, F., and S.L. Schmid. 2015. Crosstalk between Akt/GSK3β signaling and dynamin-1 regulates clathrin-mediated endocytosis in non-neuronal cells EMBO J, 34: 2131-46

Mattila, J-P, A. Shnyrova, A.C. Sundborger, E. Rodriguez Hortelano, M. Furhmans, S. Neumann, M. Muller, J.E. Hinshaw, S.L. Schmid* and V.A. Frolov*. 2015. A hemifission intermediate links two mechanistically distinct stages of membrane fission Nature, 524: 109-13

Shnyrova, A.V., P. V. Bashkirov, S.A. Akimov, T.J. Pucadyil, J. Zimmerberg, S L. Schmid and V.A. Frolov. 2013. Geometric catalysis of membrane fission driven by flexible dynamin rings. Science, 339:1433-36

Aguet, F., C. N. Antonescu, M. Mettlen, S.L. Schmid* and G. Danuser*. 2013. Advances in Analysis of Low Signal-to-Noise Images Link Dynamin and AP2 to the Functions of an Endocytic Checkpoint. Dev. Cell 126: 279-91

Chappie, J.S., J.A. Mears, S. Fung, M. Leonard, S.L. Schmid, R.A. Milligan, J.E. Hinshaw and F. Dyda. 2011. A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke. Cell 147:209-222

Liu, Y-W*, S. Neumann*, R. Ramachandran, S. M. Ferguson, T.J. Pucadyil and S.L. Schmid, 2011. Differential curvature sensing and generating activities of dynamin isoforms provide opportunities for tissue-specific regulation. Proc. Natl. Acad. Sci. 108:E234-42

Chappie, J.S., S. Acharya, M. Leonard, S.L. Schmid1 and F. Dyda1. 2010. G domain dimerization controls dynamin’s assembly-stimulated GTPase activity. Nature 465:435-40

Mettlen, M. D. Loerke, D. Yarar, G Danuser, S.L. Schmid. 2010. Cargo and adaptor specific mechanisms regulate clathrin mediated endocytosis. J. Cell Biol. 188:919-33