Dual diagnosis studies
Mood disorders with comorbid substance abuse
Many people with mood or other psychiatric disorders use drugs and/or alcohol to self-medicate. This is especially true of individuals with bipolar disorder. Our ongoing studies in this area examine whether certain medications or nutritional supplements can both curb cravings for these substances and help stabilize mood symptoms.
- Ondansetron for Bipolar and Alcohol Use Disorders
- Aripiprazole for Bipolar Disorder and Alcohol Use Disorders
- Brexpiprazole for Bipolar Depression
Our group is interested in researching how long-term corticosteroid therapy affects brain activity and function. Our group recently completed a project examining different aspects of the hippocampus (volume, biochemistry, and functioning) in patients receiving chronic prednisone therapy. A significant amount of our research examines if there are medications available that can prevent the common corticosteriod side effects of memory impairment and manic/hypomanic symptoms.