Research

Collaboration

The Phillips lab collaborates with many other researchers in its fight against protozoan parasites.

Malaria

The Phillips lab has an NIH-funded malaria drug discovery project and collaborates with Medicines for Malaria Venture (MMV), and with two academic labs, Pradip Rathod, Ph.D, of the University of Washington and Susan Charman, Ph.D. of Monash University.

The Phillips lab contributes enzymology and structural biology, the Rathod lab chemistry and parasite biology and the Charman lab pharmacology (ADME analysis).

MMV provides project advisors and supporting assays and has the pipeline and expertise required to translate our discoveries into clinical use.

African Sleeping Sickness

The Phillips lab has an NIH-funded project to develop compounds for the treatment of African sleeping sickness. This project is a collaboration with the lab of Jef De Brabander, Ph.D., and with Scynexis, Inc.

We also collaborate with the laboratoy of Ken Stuart, Ph.D., founder of the Seattle Biomedical Research Institute, to identify essential enzymes that may serve as future drug targets.

Structural Imaging

The Phillips lab also collaborates with Lani Wu, Ph.D., and Steve Altschuler, Ph.D., on an imaging project and has a long standing collaboration with Betsy Goldsmith, Ph.D., on X-ray structural studies of enzymes from the polyamine and pyrimidine biosynthetic pathways.