Publications

Publications

2013

Nalepa, G., Barnholtz-Sloan, J., Enzor, R., Dey, D., He, Y., Gehlhausen, J.R., Lehmann, A.S., Park, S.J., Yang, Y., Yang, X., Chen, S., Guan, X., Chen, Y., Renbarger, J., Yang, F.C., Parada, L.F., Clapp, W. 2013. “The tumor suppressor CDKN3 controls mitosis.” Journal of Cell Biology. Epub ahead of print.

Takeuchi, K., Gertner, M., Zhou, J., Parada, L.F., Bennett, M.V., and Zukin, R.S. 2013. “Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism.” Proceedings of the National Academy of Sciences. Vol. 110(12):4738-4743.

Mo, W., Chen, J., Patel, A., Zhang, L., Chau, V., Li, Y., Cho, W., Lim, S.K., Xu, J., Lazar, A.J., Creighton, C.J., Bolshakov, S., McKay, R.M., Lev, D., Le, L.Q., and Parada, L.F. 2013. “CXCR4 mediates autocrine cell cycle progression in NF1-associated malignant peripheral nerve sheath tumors.” Cell. Vol. 152(5):1077-1090. 

2012

Gutmann, D.H., Parada, L.F., Silva, A.J., Ratner, N. 2012. “Neurofibromatosis type 1: modeling CNS dysfunction.” Journal of Neuroscience. Vol. 32(41):14087-14093.

Li, Y., Yui, D., Luikart, B.W., McKay, R.M., Li. Y., Rubenstein, J.L., and Parada, L.F. 2012. “Conditional ablation of Brain-derived Neurotrophic Factor-TrkB signaling impairs striatal neuron development.” Proceedings of the National Academy of Sciences. Vol. 109(38):15491-15496.

Kim. T.H., Song, J., Alcantara Llaguno, S.R., Murnan, E., Liyanarachchi, S., Palanichamy, K., Yi, J.Y., Viapiano, M.S., Nakano, I., Yoon, S.O., Wu, H., Parada, L.F., and Kwon, C.H. 2012. “Suppression of peroxiredoxin 4 in glioblastoma cells increases apoptosis and reduces tumor growth.” PLoS One. Vol. 7(8):e42818.

“A restricted cell population propagates glioblastoma growth following chemotherapy.”
Chen, J., Li, Y., Yu, T-S., McKay, R.M., Burns, D.K., and Parada, L.F. Nature, 2012; Vol. 488, p. 522-526.

“Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis.”
Amiri, A., Cho, W., Zhou, J., Birnbaum, S.G., Sinton, C.M., McKay, R.M., and Parada, L.F. Journal of Neuroscience, 2012; Vol. 32(17):5880-5890.

"Malignant glioma: lessons from genomics, mouse models and stem cells."
Chen, J., McKay, R.M., and Parada, L.F. Cell, 2012; Vol. 149(1):36-47.

“Neurofibromin regulation of ERK signaling modulates adult hippocampal neurogenesis and behavioral effects of antidepressants.”

2011

Li, Y., Li, Y., McKay, R.M., Riethmacher, D., and Parada, L.F. Journal of Neuroscience, 2012; Vol 32(10):3529-3539.
“Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle.”
Zhou, J., Shrikhande, G., Xu, J., McKay, R.M., Burns, D.K., Johnson, J.E., and Parada, L.F. Genes & Development. 2011. Vol. 25(15):1595-1600.

“Susceptible stages in Schwann cells for NF-1 associated plexiform neurofibroma development.”
Le, L.Q., Shipman, T., Chen, Z., Suter, U., and Parada, L.F. Cancer Research, 2011; Vol. 71(13):4686-4695.

2010 and earlier

“Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas.”
Le, L., Shipman, T., Burns, D.K., and Parada, L.F. Cell Stem Cell, 2009; Vol. 4(5): 453-463.

“Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model”.
Alcantara Llaguno, S., Chen, J., Kwon, C.H., Jackson, E.L., Li, Y., Burns, D.K., Alvarez-Buylla, A., and Parada, L.F. Cancer Cell, 2009; Vol. 15(1): 45-56.

“Trk B regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment.”
Li, Y., Luikart, B.W., Birnbaum, S., Chen, J., Kwon, C.H., Kernie, S.G., Bassel-Duby, R. and Parada, L.F. Neuron, 2008; Vol. 59(3): 399-412.

“Pten Haploinsufficiency Accelerates Formation of High Grade Astrocytomas.”
Kwon, C.H., Zhao, D., Chen, J., Alcantara, S., Li, Y., Burns, D., Mason, R., Lee, E. Y-H., Wu, H. and Parada, L.F. Cancer Research, 2008; Vol. 68(9): 3286-3294.

“Pten regulates neuronal arborization and social interaction in mice.”
Kwon, C.H., Luikart, B.W., Powell, C.M., Zhou, J., Matheny, S.A., Zhang, W., Li, Y., Baker, S.J. and Parada, L.F. Neuron, 2006; Vol. 50(3): 377-388.