Research

Research

Metastasis — the spread of cancer cells from primary tumor to distal organs — is responsible for more than 90 percent of cancer-related deaths. Early tumor detection and diagnosis has prolonged patient survival, but when the disease relapses as widespread metastasis it poses a major clinical challenge.

The Malladi lab studies how disseminated cancer cells survive and give rise to overt metastasis using several model systems representing cancers with metastatic latency: lung, breast, and renal adenocarcinomas.

Our overarching goal is to develop improved diagnostic and therapeutic modalities for treating residual disease and metastasis.