Publications

Publications for John MacMillan, Ph.D.

2014

2013

2012

2011

2010

  • Towards patient-based cancer therapeutics
    The Cancer Target Discovery and Development Network, Stuart L Schreiber, Alykhan F Shamji, Paul A Clemons, Cindy Hon, Angela N Koehler, Benito Munoz, Michelle Palmer, Andrew M Stern, Bridget K Wagner, Scott Powers, Scott W Lowe, Xuecui Guo, Alex Krasnitz, Eric T Sawey, Raffaella Sordella, Lincoln Stein, Lloyd C Trotman, Andrea Califano, Riccardo Dalla-Favera, Adolfo Ferrando, Antonio Iavarone, Laura Pasqualucci, José Silva, Brent R Stockwell, William C Hahn, Lynda Chin, Ronald A DePinho, Jesse S Boehm, Shuba Gopal, Alan Huang, David E Root, Barbara A Weir, Daniela S Gerhard, Jean Claude Zenklusen, Michael G Roth, Michael A White, John D Minna, John B MacMillan, and Bruce A Posner
    Nat Biotechnol., 2010, 9, pp 904–906

2009

Prior to UTSW

  • Maloney, K.; MacMillan, J.B.; Kauffman, C.; Jensen, P.R.; DiPasquale, A.; Fenical, W. Lodopyridone, a Structurally-Unprecedented Alkaloid from a Marine Actinomycete Org. Lett., 2009 11, 5422-5424.
  • Hughes, C.C.; MacMillan, J.B.; Gaudencio, S.P.; Jensen, P.R.; Fenical, W. The Ammosamides, Structures of Potent Cytotoxins from a Marine-Derived Streptomyces sp. Angew. Chemie Int. Ed., 2009, 48, 725-727.
  • Hughes, C.C.; MacMillan, J.B.; Gaudencio, S.P. Fenical, W.; LaClair, J.J., Covalent Modification of Myosin by Ammosamides A and B Angew. Chemie Int. Ed., 2009, 48, 728-732.
  • Newton, G.L.; Jensen, P.R., MacMillan, J.B., Fenical, W. Fahey, R.C. A homolog of mycothiol can replace mycothiol as the dominant thiol during secondary metabolite production in marine actinomycetes Archives of Microbiology, 2008, 190, 547-557.
  • MacMillan, J.B.; Zhou, G.Z.; Skepper, C.K. Molinski, T.F. Phorbasides A-E, Cytotoxic Chlorocyclopropane Macrolide Glycosides from the Marine Sponge Phorbas sp. CD Determination of C-Methyl Sugar Configurations J. Org. Chem. 2008, 73, 3699-3706.
  • Skepper, C.; MacMillan, J.B.; Zhou, G.Z.; Masuno. M.N.;Molinski, T.F. Chlorocyclopropane Macrolides from the Marine Sponge Phorbas sp.: Assignment of Configurations of Phorbasides A and B by Quantitative CD JJ. Am. Chem. Soc. 2007, 129, 1450-1451.
  • Linington, R.G.; Robertson, M.; Gauthier, A.; Finlay, B.B.; MacMillan, J.B.; Molinski, T.F.; van Soest, R.; Andersen, R.J. Caminosides B-D, Antimicrobial Glycolipids Isolated from the Marine Sponge Caminus sphaeroconia. Journal of Natural Products, 2006, 69, 173-177.
  • Cueto, M.; MacMillan. J.B.; Jensen, P.R.; Fenical, W. Tropolactones A-D, Cytotoxic Terpenes Isolated from a Marine-Derived Fungus Phytochemistry, 2006, 67,1826-1831.
  • Makarieva, T.N.; Denisenko, V.A.; Dmitrenok, P.S.; Guzii, A.G.; Santalova, E.A.; Stonik, V.A. MacMillan, J.B.; Molinski, T.F., Oceanalin A, a Hybrid Bifunctionalized Sphingoid Tetrahydroisoquinoline Glycoside from the Marine Sponge Oceanapia sp. Org. Lett. 2005, 7, 2897-2900.
  • MacMillan, J.B.; Molinski T.F. Majusculoic acid, a Brominated Cyclopropyl Fatty Acid from a Marine Cyanobacterial Mat AssemblageJ. Nat. Prod, 2005, 68, 604-606.
    Kossuga, M.H.; MacMillan, J.B.; Rogers, E.W.; Molinski, T.F.; Nascimento, G.G.F.; Rocha, R.M.; Berlinck, R.G.S. (2S,3R)-2-Aminododecan-3-ol, a New Antifungal Agent the Ascidian Clavelina oblonga J. Nat. Prod. 2004, 67, 1879-1881.
  • MacMillan, J.B.; Linington, R.G.; Andersen, R.J.; Molinski, T.F. Stereochemical Assignment in Acyclic Lipids Across Long Distance by Circular Dichroism: Absolute Stereochemistry of the Aglycone of Caminoside A Angew. Chemie. Int. Ed. 2004, 43, 5946-5951.
  • Liu, C.; Masuno, M.N.; MacMillan, J.B.; Molinski, T.F. Enantioselective Total Synthesis of (+)-Milnamide A and Evidence of Its Autoxidation to (+)-Milnamide D. Angew. Chemie. Int. Ed. 2004, 43, 5951-5954.
  • MacMillan, J.B.; Molinski, T.F. Long-Range Stereo-Relay: Relative and Absolute Configuration of 1,n-Glycols from Circular Dichroism of Liposomal Porphyrin Esters J. Am. Chem. Soc. 2004, 126, 9944-9945.
  • MacMillan, J.B.; Ernst-Russell, M.A.; deRopp, J.S.; Molinski, T.F. Lobocyclamides A-C, Lipopeptides from a Cryptic Cyanobacterial Mat Containing Lyngbya confervoides J. Org. Chem. 2002, 67, 8210-8215.
  • Nicholas, G.M.; Li, R.H.; MacMillan, J.B.; Molinski, T.F. Antifungal Activity of Bifunctional Sphingolipids. Intramolecular Synergism within Long-Chain a,w-Bis Aminoalcohols Biorg. Med. Chem Lett. 2002, 12, 2159-2162.
  • MacMillan, J.B.; Molinski, T.F. Lobocyclamide B from Lyngbya confervoides. Configuration and Asymmetric Synthesis of b-Hydroxy-a-Amino Acids by (-)-Sparteine-Mediated Aldol Addition Org. Lett. 2002, 4, 1883-1886.
  • MacMillan, J.B.; Molinski, T.F. Caylobolide A, a Unique 36-Membered Macrolactone from a Bahamian Lyngbya majuscule Org. Lett. 2002, 2, 1535-1538.
    Moon, S.S.; MacMillan, J.B.; Olmstead, M..M.; Ta. T.A.; Pessah, I.N.; Molinski, T.F. (+)-7S-Hydroxyxestospongin A from the Marine Sponge Xestospongia sp. and Absolute Configuration of (+)-Xestospongin D J. Nat Prod. 2002, 65, 249-254.
  • MacMillan, J.B.; Trousdale, E.K.; Molinski, T.F. Structure of (-)-Neodysidenin from Dysidea herbacea. Implications for Biosynthesis of 5,5,5-Trichloroleucine Peptides Org. Lett, 2000, 2, 272-273.
  • MacMillan, J.B.; Molinski, T.F. Herbacic Acid, a Simple Prototype of 5,5,5-Trichloroleucine Metabolites from the Sponge Dysidea herbacea J. Nat. Prod.1999, 63, 155-157.