Selected Publications
Lu, QR, Sun, T., Zhu, Z., Ma, N., Garcia, M., Stiles, CD and Rowitch, D. (2002) " Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection " CELL, 109, 75-86.
Lu, QR, Cai, L., Rowitch, D., Cepko, CL. and Stiles, CD. (2001) "Ectopic Expression of Olig1 Promotes Oligodendrocyte Formation and reduces Neuronal Survival in Developing Mouse Cortex" Nature Neuroscience., 4, 973-974.
Lu, QR, Park, J., Noll, E, Chan, JA, Alberta, J., Yuk, D., Alzamora, MG, Louis, DN, Stiles, CD, Rowitch, DH. and Black, PM. (2001) "Oligodendrocyte Lineage Genes (OLIG) as Molecular Markers for Human Glial Brain Tumors". Proc. Nat. Acad. Sci. USA , 98, 10851-10856.
Lu, QR, Yuk, D., Alberta, JA., Zhu, Z., Pawlitzky, I., Chan, J., McMahon, AP., Stiles, CD. and Rowitch, DH. (2000) “Sonic Hedgehog–Regulated Oligodendrocyte Lineage Genes Encoding bHLH Proteins in the Mammalian Central Nervous System” NEURON, 25, 317–329
Xin, M., T. Yue, Z. Ma, F. Wu, A. Gow, and Lu, QR. (2005) "Myelinogenesis and axonal recognition by oligodendrocytes in brain are uncoupled in Olig1-null mice." J. Neurosci, 25,1354-1366.
Yue, T., Xian, K., Hurlock, E., Xin, M., Kernie, S., Parada, L.F. and Lu, QR (2006). “A Critical Role of Dorsal Progenitors for Cortical Myelination". J. of Neurosci., 26(4). 1275-1280.
Wang, S., Dulin, J., Wu, H., Hurlock, E., Lee, S., Jansson, K., and Lu, QR. (2006). "An Oligodendrocyte-Specific Zinc Finger Transcription Regulator Cooperates With Olig2 To
Promote Oligodendrocyte Differentiation" Development, 2006;133(17):3389-98.
Cai, J., Chen Y., Cai, W., Hurlock, E., Wu, H., Kernie, S. G., Parada L. F. and Lu, QR. (2007). " A Crucial Role For Olig2 In White Matter Astrocyte Development" Development,134, 1887-1899 (2007).
Chen, Y., V. Balasubramaniyan, M. Tallquist, J. Li and Lu, QR (2007) Isolation and Culture of Rat and Mouse Oligodendrocyte Precursor Cells. Nature Protocols, 2, 1044-1051, 2007.
Lu, QR., Balasubramaniyan, V. and Peru, R.L., (2007) "Oligodendrocyte Myelination in the Mammalian CNS" Functional Development and Embryology, 1 (2):117-128.
Peru RL, Mandrycky N, Nait-Oumesmar B, Lu QR. (2008) Paving the Axonal Highway: From Stem Cells to Myelin Repair. Stem Cell Rev. 4(4):304-18.
Chen,Y., Miles, D., Hoang, J., Shi, J., Kernie, S.G. and Lu, QR (2008). “The bHLH Gene Olig2 Is Required for Reactive Astrocyte Proliferation After Cortical Injury”. J. Neurosci. 2008, 28(43):10983-9.
Ye, F., Chen, Y., Hoang, J. Montgomery, R., Zhao, X., Bu, H., Taketo, M., van Es, J., Clevers, H., Hsieh, J., Bassel-Duby, R., Olson, E., and Lu, QR (2009) " Histone Deacetylases 1 and 2 Regulate Oligodendrocyte Differentiation By Disrupting b-Catenin TCF Interaction". Nat Neurosci. 2009 Jul;12(7):829-38.
Chen Y., Wu, H., Wang, S., Hu, T., Cai, J., Hoang, J., Escobar, SS., Arnett, HA., Trapp, BD., Karandikar, N., Hsieh, J. and Lu, QR (2009) “The oligodendrocyte-specific G-protein coupled receptor GPR17 is a cell-intrinsic timer of myelination” Nat. Neurosci. 2009 Nov;12(11):1398-406.
Zhao, X., He, X., Han, X., Yu, Y., Ye, F., Chen, Y., Hoang, T., Xu, X., Mi, Q.S., Xin, M., Wang, F., Appel, B. and Lu, Q.R., "MicroRNA-mediated control of oligodendrocyte differentiation" Neuron, 65:612-626, March 2010.
Chen Y, Wang H, Yoon SO, Xu X, Hottiger MO, Svaren J, Nave KA, Kim HA, Olson EN, Lu QR. "HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination" Nat Neurosci. 2011 Apr;14(4):437-41. Epub 2011 Mar 20.
To access any of the publications referenced on this website please visit http://www.ncbi.nlm.nih.gov/PubMed