Ph.D. – Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China

B.S. – Department of Chemistry, Fudan University, China

Research

My research interest is to explore the structure-activity relationship of diazirine-containing carbohydrate analogs on incorporation efficiency onto cell surface glycans. We will evaluate the incorporation efficiency by FACS as well as photocrosslinking of diazirine with its binding partners.

Publications

Wang, Y.; Zhang, Y.; Zhu, Z.; Zhu, S.; Li, Y.; Li, M.; Yu, B. “Exploration of the correlation between the structure, hemolytic activity, and cytotoxicity of steroid saponins”, Bioorg. Med. Chem. 2007, 15, 2528-2532.

Wang, Y.; Zhang, Y.; Yu, B. “The cytotoxicity of saponins correlates with their cellular internalization”, ChemMedChem, 2007, 2, 288-291. ChemMedChem Cover Letter.

Li, W.; Qiu, Z.; Wang, Y.; Zhang, Y.; Li, M.; Yu, J.; Zhang, L.; Zhu, Z.; Yu, B. “Synthesis, cytotoxicity, and hemolytic activity of 6'-O-substituted dioscin derivatives”, Carbohydr. Res. 2007, 342, 2705-2715.