Ph.D. – Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China
B.S. – Department of Chemistry, Fudan University, China
My research interest is to explore the structure-activity relationship of diazirine-containing carbohydrate analogs on incorporation efficiency onto cell surface glycans. We will evaluate the incorporation efficiency by FACS as well as photocrosslinking of diazirine with its binding partners.
Wang, Y.; Zhang, Y.; Zhu, Z.; Zhu, S.; Li, Y.; Li, M.; Yu, B. “Exploration of the correlation between the structure, hemolytic activity, and cytotoxicity of steroid saponins”, Bioorg. Med. Chem. 2007, 15, 2528-2532.
Wang, Y.; Zhang, Y.; Yu, B. “The cytotoxicity of saponins correlates with their cellular internalization”, ChemMedChem, 2007, 2, 288-291. ChemMedChem Cover Letter.
Li, W.; Qiu, Z.; Wang, Y.; Zhang, Y.; Li, M.; Yu, J.; Zhang, L.; Zhu, Z.; Yu, B. “Synthesis, cytotoxicity, and hemolytic activity of 6'-O-substituted dioscin derivatives”, Carbohydr. Res. 2007, 342, 2705-2715.