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mTORC1

We study how mTORC1 senses nutrients to control cell growth and metabolism.

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mTORC1 and Human Disease

Alterations in mTORC1 signaling can cause metabolic diseases and cancer. We aim to understand the molecular mechanisms involved in these pathways.

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Amino Acid Sensing

We seek to identify the mechanisms by which amino acids activate mTORC1.

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Location, Location, Location!

mTORC1 is activated at the lysosome. We want to understand why the lysosome is required for mTORC1 activation.