Preparing and using recombinant viral vectors requires specialized and expensive techniques, reagents and biosafety-compliant laboratory space not available to every investigator. The Vector Core serves as a repository of materials, information and expertise to produce recombinant vectors, both viral and non-viral.
- To provide a Core Laboratory for the construction, purification and characterization of recombinant vectors containing transgenes for use as in vitro and in vivo gene transfer reagents. These systems include both non-viral (expression plasmid) and viral (recombinant retrovirus and recombinant adenovirus) technologies.
- To provide access to the technology associated with the use of these gene transfer systems to investigators in an efficient and user-friendly manner.