Publications

Publications

2014

Singh S, DC Canseco, SM Manda, JM Shelton, RR Chirumamilla, SC Goetsch, Q Ye, RD Gerard, JW Schneider, JA Richardson, BA Rothermel, PPA Mammen. (2014) Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration, Proc Natl Acad Sci USA 111:E129-E138.

Xu M, JS Nagati, J Xie, J Li, H Walters, Y-A Moon, RD Gerard, C-L Huang, SA Comerford, RE Hammer, JD Horton, R Chen, JA Garcia. A mammalian acetate switch regulates stress erythropoiesis. Nature Medicine, in press.

2013

Nelson BT, X Ding, J Boney-Montoya, RD Gerard, SA Kliewer, MT Andrews. (2013) Metabolic hormone FGF21 is induced in ground squirrels during hibernation but its overexpression is not sufficient to cause torpor. PLOS Biology 8:e53574. PMCID: PMC3534659.

Saddar S, V Carriere, WR Lee, K Tanagaki, IS Yuhanna, S Parathath, E Morel, M Warrier, JK Sawyer, RD Gerard, RE Tremel, JM Brown, M Connelly, C Mineo, PW Shaul. (2013) Scavenger receptor class B type I is a plasma membrane cholesterol sensor. Circ Res 112:140-151.

2012

Battiprolu PK, B Hojayev, N Jiang, ZV Wang, X Luo, M Iglewski, JM Shelton, RD Gerard, BA Rothermel,TG Gillette, S Lavandero, JA Hill. (2012) Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy. J Clin Invest 122:1109-1118. PMID: 22326951.

Wei W, PA Dutchak, X Wang, X Ding, X Wang, AL Bookhout, R Goetz, M Mohammadi, RD Gerard, PC Dechow, DJ Mangelsdorf, SA Kliewer, Y Wan. (2012) Fibroblast growth factor 21 promotes bone loss by potentiating the effects of PPARγ. Proc Natl Acad Sci USA 109:3143-3148. PMID: 22315431.

Williams KC, NE Renthal, JC Condon, RD Gerard, CR Mendelson. (2012) miR-200a Serves a Key Role in the Decline of Progesterone Receptor Function Leading to Term and Preterm Labor. Proc Natl Acad Sci USA 109:7529-7534. PMCID: PMC3358858.

Card PB, RT Hogg, C Gil del Alcazar, RD Gerard. (2012) MicroRNA silencing improves the tumor specificity of adenoviral transgene expression. Cancer Gene Therapy 19:451-459. PMID: 22555510.

Ballard EN, VT Trinh, RT Hogg, RD Gerard. (2012) Peptide targeting of adenoviral vectors to augment tumor gene transfer. Cancer Gene Therapy 19:476-488. PMID: 22595794.

Williams, KC, NE Renthal, RD Gerard, CR Mendelson. (2012) The microRNA (miR)199a/214 cluster mediates opposing effects of progesterone and estrogen on uterine contractility during pregnancy and labor. Mol Endocrinol 26:1857-1867.

Kir S, Y Zhang, RD Gerard, SA Kliewer, DJ Mangelsdorf. (2012) Nuclear receptors HNF4a and LRH-1 cooperate in regulating Cyp7a1 in vivo. J Biol Chem 287:41334-41341.

Huang GN, JE Thatcher, J McAnally, Y Kong, X Qi, W Tan, JM DiMaio, JF Amatruda, RD Gerard, JA Hill, R Bassel-Duby, EN Olson. (2012) C/EBP transcription factors mediate epicardial activation during heart development and injury. Science 338:1599-1603.

ShiX, AM Wallis, RD Gerard, KA Voelker, RW Grange, RA DePinho, MG Garry, DJ Garry.(2012) Foxk1 promotes cell proliferation and represses myogenic differentiation by regulating Foxo4 and Mef2. J Cell Sci 125:5329.

Chen R, M Xu, RT Hogg, J Li, B Little, RD Gerard, JA Garcia. (2012) The acetylase/deacetylase couple CREB binding protein/sirtuin 1 controls hypoxia hypoxia-inducible factor 2 signaling. J Biol Chem 287:30800-30811.

2011

Hogg, RT, PA Thorpe, RD Gerard. (2011) Retargeting adenoviral vectors to improve gene transfer into tumors. Cancer Gene Ther 18:275-287. PMID: 21183946.

Chen R, EM Dioum, RT Hogg, RD Gerard, JA Garcia. (2011) Hypoxia increases Sirtuin 1 expression in a hypoxia inducible factor-dependent manner. J Biol Chem 286:13869-13878. PMID: 21345792.

Pothoff MJ, J Boney-Montoya, M Choi, T He, N Sunny, S Satapati, K Suino-Powell,HE Xu, RD Gerard, BN Finck, SC Burgess, DJ Mangelsdorf, SA Kliewer. (2011) FGF15/19 regulates hepatic glucose metabolism by inhibiting the CREB-PGC-1a pathway. Cell Metabolism 13:729-738. PMID: 21641554.

Pashkov V, J Huang, VK Parameswara , W Kedzierski, DM Kurrasch, GG Tall, V Esser, RD Gerard, K Uyeda, HC Towle, TM Wilke. (2011) Regulator of G protein signaling (RGS16) inhibits hepatic fatty acid oxidation in a carbohydrate response element-binding protein (ChREBP)-dependent manner. J Biol Chem 286:15116-15125. PMID: 21357625.

AgarwalAK, S Sukumaran, VA Cortés, K Tunison, D Mizrachi, S Sankella, RD Gerard, JD Horton, A Garg. (2011) Human 1-Acylglycerol-3-phosphate o-acyltransferase isoforms 1 and 2: Biochemical characterization and inability to rescue hepatic steatosis in Agpat2-/- gene lipodystrophic mice. J Biol Chem 286:37676-37691. PMID: 21873652.

2010

Chang AN, G Chen, RD Gerard, KE Kamm, JT Stull. (2010) Cardiac myosin is a substrate for zipper-interacting protein kinase (ZIPK). J Biol Chem 285:5122-5126. PMID: 20038585.

Hogg RT, JA Garcia, RD Gerard. (2010)Adenoviral targeting of gene expression to tumors. Cancer Gene Ther 17:375-386. PMID: 20139924.

Small E, J O'Rourke, V Moresi, L Sutherland, J McAnally, RD Gerard, J Richardson, E Olson. (2010)Regulation of PI3 kinase/akt signaling by muscle-enriched microRNA-486. Proc Natl Acad Sci USA 107:4218-4223. PMID: 20142475.

Oh M, A Dey, RD Gerard, JA Hill, BA Rothermel. (2010) The CCAAT/enhancer binding protein beta (C/EBP!) cooperates with NFAT to control expression of the calcineurin regulatory protein RCAN1-4. J Biol Chem 285:16623-16631. PMID: 20371871.

Small E, J Thatcher, L Sutherland, H Kinoshita, RD Gerard, J Richardson, M DiMaio, H Sadek, K Kuwuhara, E Olson. (2010) Myocardin-related transcription factor-A controls myofibroblast activation and fibrosis in response to myocardial infarction. Circ Res 107:294-304. PMID: 20558820.

Maitra M, Y Wang, RD Gerard, C Mendelson, CK Garcia. (2010) Surfactant protein A2 mutations associated with pulmonary fibrosis lead to protein instability and endoplasmic reticulum stress. J Biol Chem 285:22103-22113. PMID: 20466729.

Bekeredjian R, CB Walton, KA MacCannell, J Ecker, F Kruse, JT Outten, D Sutcliffe, RD Gerard, RK Bruick, RV Shohet. (2010) Conditional HIF-1α expression produces a reversible cardiomyopathy. PLoS ONE 5(7):e11693. PMID: 20657781.

Renthal NE, C-C Chen, KC Williams, RD Gerard, J Prange-Kiel, CR Mendelson. (2010) The miR-200 family and targets, Zeb1 and Zeb2, modulate uterine quiescence and contractility during pregnancy and labor. Proc Natl Acad Sci USA 107;20828-20833. PMID: 21079000.

2009

Dioum EM, R Chen, MS Alexander, Q Zhang, RT Hogg, RD Gerard, JA Garcia. (2009) Regulation of hypoxia inducible factor 2α signaling by the stress-responsive deacetylase sirtuin 1. Science 324:1289-1293. PMID: 19498162.

EspiraL, L Lamoureux, SC Jones, RD Gerard, IMC Dixon, MP Czubryt. (2009) The basic helix-loop-helix transcription factor scleraxis regulates fibroblast-mediated collagen synthesis. J Mol Cell Card 47:188-195. PMID: 19362560.

2008

Vasalatiy O, RD Gerard, P Zhao, X Sun, AD Sherry. (2008) Labeling of adenovirus particles with PARACEST agents. Bioconj Chem 19:598-606. PMID: 18254605.

Tannous P, H Zhu, JL Johnstone, JM Shelton, NS Rajasekaran, IJ Benjamin, L Nguyen, RD Gerard, B Levine, BA Rothermel, JA Hill (2008) Autophagy is an adaptive response in desmin-related cardiomyopathy.Proc Natl Acad Sci USA 105:9745-9750. PMID: 18621691.

Older

Henry, LJ, D Xia, M Wilke, J Deisenhofer, RD Gerard. (1994) Characterization of the knob domain of the adenovirus 5 fiber protein expressed in E. coli. J Virol 68:5239-5246. PMID: 8035520.

Xia, D, L Henry, RD Gerard, J Deisenhofer (1994) Structure of the adenovirus 5 fiber knob domain at 1.7Å resolution. Structure 2:1259-1270. PMID: 7704534.

Gerard, RD and RS Meidell (1995) Adenovirus vectors in DNA Cloning- A Practical Approach: Mammalian Systems, BD Hames and D Glover, eds., pp. 285-307, Oxford University Press, Oxford.

Xia, D, L Henry, RD Gerard and J Deisenhofer (1995) Structure of the receptor binding domain of adenovirus type 5 fiber protein, in Molecular Repertoir of Adenoviruses I, Current Topics in Microbiology and Immunology, W. Doerfler and P Boehm, eds., pp. 39-46, Springer Verlag, Berlin PMID: 7555059.

Israel B, R Pickles, D Segal, RD Gerard, S Sweeney. (2001) Enhancement of adenoviral vector entry into CD70-positive B cell lines using bispecific CD70/adenovirus fiber antibody. J Virol 75: 5215-5221. PMID:11333903.