Robert Gerard, Ph.D.
I have constructed and used recombinant adenovirus vectors for gene transfer in vitro and in vivo for over 25 years for a variety of purposes. I first learned the techniques of constructing these vectors as a postdoc at Cold Spring Harbor Laboratory. As a new faculty member at UT Southwestern in the 1980s, I expanded my cardiovascular research program to include adenoviral gene transfer, both in cell culture and in intact animals. Since the early 1990s I have been interested in adenovirus targeting to tumors in vivo, and our early work focused on basic adenovirus structure and expression of transgenes using specific promoter elements. Currently we are working to develop “smart” adenoviruses to target tumors in vivo.
Richard Hogg, L.V.T.
I have worked in the Gerard lab since 2004. I am trained as a licensed veterinary technician and perform all in vivo work in the lab using mouse tumor models. I also perform molecular analyses of gene transfer and expression using biochemical assays, chemiluminescent imaging and real-time PCR.