Reto Fiolka is an Assistant Professor at UT Southwestern in the Department of Cell Biology. He oversees the development of advanced light microscopes with a focus on 3D live cell imaging in physiologically relevant microenvironments. This has led to the creation of novel light-sheet technologies that enable isotropic spatial resolution over large volumes and rapid image acquisition. Further research competence and interest include adaptive optics for high-resolution imaging in complex samples and super-resolution microscopy.
Dr. Fiolka received a master's degree in mechanical engineering at ETH Zurich in 2006. He did his Ph.D. thesis at the institute of Nanotechnology at ETH Zurich in optical microscopy. From 2009 – 2013, he conducted postdoctoral research at the Howard Hughes Medical Institute's Janelia Farm Research Campus under the late Dr. Mats Gustafsson, working on 3D structured illumination microscopy; he later worked under Dr. Meng Cui on adaptive optics. Reto Fiolka joined the Department of Cell Biology at UT Southwestern in 2013 as an instructor and worked on high-resolution light sheet microscope technologies. In 2016, after receiving a CPRIT recruitment award, he became an assistant professor.
Bo-Jui Chang is an Assistant Instructor in Department of Cell Biology at UT Southwestern. He is very interested in Bio-imaging and he particularly specializes in light sheet microscopy (LSM) and super-resolution structured illumination microscopy (SIM). Currently, he focuses on (1) collaborating with biologists to study behaviors of cells, tissues, embryos, .etc in physiologically relevant environments, and (2) developing advanced light sheet microscopes and structured illumination microscopes.
Bo-Jui was born and raised in Taiwan. He received his Ph.D. degree in Electro-Optical Engineering from National Chiao Tung University in Taiwan in 2006. He focused on the development and application of optical tweezers during his Ph.D. From 2007 – 2011 he worked on SIM in Dr. Su-Yu Chiang’s group at National Synchrotron Radiation Research Center, Hsinchu, Taiwan. From 2011 – 2016 he worked on LSM and implemented SIM in LSM in Dr. Ernst H.K. Stelzer’s group in Frankfurt, Germany. He was also an Adjunct Investigator from 2013- 2015 in the Cluster of excellent Frankfurt Macromolecular Complexes. From 2016 – 2017 he worked on lattice light sheet microscope in Dr. Bi-Chang Chen’s group in Taipei, Taiwan. He joined Dr. Reto Fiolka’s group since Sep. 2017. Outside the lab, Bo-Jui likes almost all kinds of sports, especially baseball/softball. He is also a big fan of Star Trek.
Kevin Dean was born and raised in Weed, California. He received his B.A. in chemistry from Willamette University in 2006, and his Ph.D. in biochemistry from the University of Colorado in 2013. His graduate work focused on improving the total photon output of red fluorescent proteins using a combination of multiparametric microfluidic cell sorters, spectroscopy, and directed evolution.
Today, he develops and implements light-sheet microscopy and computer vision techniques in an effort to elucidate the mechanisms of cytoskeletal and GTPase dynamics in 3D tissue-like microenvironments. In 2016, he received a Ruth L. Kirschstein National Research Service Award from the National Institutes of Health. Outside the lab, Kevin enjoys mountain biking, skiing, and photography.
Meghan studies cell migration within three-dimensional matrices by developing image analysis techniques for high-resolution light-sheet microscopy.