Transcription Elongation Control by the 7SK snRNP Complex: Releasing the Pause.
McNamara RP, Bacon CW, D'Orso I Cell Cycle 2016 May 0
7SKiing on chromatin: move globally, act locally.
D'Orso I RNA Biol 2016 Apr 0
Genome-wide analysis of KAP1, the 7SK snRNP complex, and RNA polymerase II.
McNamara RP, Guzman C, Reeder JE, D'Orso I Genom Data 2016 Mar 7 250-5
KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.
McNamara RP, Reeder JE, McMillan EA, Bacon CW, McCann JL, D'Orso I Mol. Cell 2016 Jan 61 1 39-53
Functional interplay between PPM1G and the transcription elongation machinery.
Gudipaty SA, D'Orso I RNA Dis 2016 3 1
HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells.
Reeder JE, Kwak YT, McNamara RP, Forst CV, D'Orso I Elife 2015 Oct 4
PPM1G binds 7SK RNA and Hexim1 to block P-TEFb assembly into the 7SK snRNP and sustain transcription elongation.
Gudipaty SA, McNamara RP, Morton EL, D'Orso I Mol. Cell. Biol. 2015 Aug
Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation.
McNamara RP, McCann JL, Gudipaty SA, D'Orso I Cell Rep 2013 Dec 5 5 1256-68
Transition Step during Assembly of HIV Tat:P-TEFb Transcription Complexes and Transfer to TAR RNA.
D'Orso I, Jang GM, Pastuszak AW, Faust TB, Quezada E, Booth DS, Frankel AD Mol. Cell. Biol. 2012 Dec 32 23 4780-93
Transcription control by long non-coding RNAs.
Faust T, Frankel A, D'Orso I Transcription 2012 Mar 3 2