Publications for Richard Bruick, Ph.D.

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Featured Publications

Activation of the HIF prolyl hydroxylase by the iron chaperones PCBP1 and PCBP2.

Nandal A, Ruiz JC, Subramanian P, Ghimire-Rijal S, Sinnamon RA, Stemmler TL, Bruick RK, Philpott CC Cell Metab. 2011 Nov 14 5 647-57

Conditional HIF-1alpha expression produces a reversible cardiomyopathy.

Bekeredjian R, Walton CB, MacCannell KA, Ecker J, Kruse F, Outten JT, Sutcliffe D, Gerard RD, Bruick RK, Shohet RV PLoS ONE 2010 5 7 e11693

Maintaining Mammalian iron and oxygen homeostasis: sensors, regulation, and cross-talk.

Salahudeen AA, Bruick RK Ann. N. Y. Acad. Sci. 2009 Oct 1177 30-8

Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.

Scheuermann TH, Tomchick DR, Machius M, Guo Y, Bruick RK, Gardner KH Proc. Natl. Acad. Sci. U.S.A. 2009 Jan 106 2 450-5

JMJD6 is a histone arginine demethylase.

Chang B, Chen Y, Zhao Y, Bruick RK Science 2007 Oct 318 5849 444-7

Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of insigs.

Nguyen AD, McDonald JG, Bruick RK, DeBose-Boyd RA J. Biol. Chem. 2007 Sep 282 37 27436-46

Non-heme dioxygenases: cellular sensors and regulators jelly rolled into one?

Ozer A, Bruick RK Nat. Chem. Biol. 2007 Mar 3 3 144-53

Hypoxia-inducible factors Per/ARNT/Sim domains: structure and function.

Scheuermann TH, Yang J, Zhang L, Gardner KH, Bruick RK Meth. Enzymol. 2007 435 3-24

Dioxygenases as O2-dependent regulators of the hypoxic response pathway.

Dann CE, Bruick RK Biochem. Biophys. Res. Commun. 2005 Dec 338 1 639-47

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor.

Yang J, Zhang L, Erbel PJ, Gardner KH, Ding K, Garcia JA, Bruick RK J. Biol. Chem. 2005 Oct 280 43 36047-54

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