Much effort has recently been placed on harnessing the power of the patient’s immune system to recognize and destroy tumor cells, in the same fashion that the immune system neutralizes infectious pathogens. As vaccination has been used as a potent and cost effective method to block the spread and severity of infectious disease, it is hoped that vaccination against tumor antigens will provide a similar success in the fight against cancer.
The Brown Lab is taking multiple approaches to develop effective anti-cancer immunotherapies. We are developing strategies to deliver antigens to specialized antigen presenting cells of the immune system to generate a rapid and robust immune response against tumors. We are also developing a novel non-viral therapy designed to generate a secondary immune response toward the tumor.