Collaboration

Collaboration

SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer.
Suresh S, Durakoglugil D, Zhou X, Zhu B, Comerford S, Xing C, Xie XJ, York B, O'Donnell KA. PLoS genetics. 2017; 13:e1006650.

Hypoxia induces heart regeneration in adult mice.
Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, Shah AM, Zhang H, Faber JE, Kinter MT, Szweda LI, Xing C, Hu Z, Deberardinis RJ, Schiattarella G, Hill JA, Oz O, Lu Z, Zhang CC, Kimura W, Sadek HA. Nature. 2017; 541:222-227.

Homozygous LIPE mutation in siblings with multiple symmetric lipomatosis, partial lipodystrophy, and myopathy.
Zolotov S, Xing C, Mahamid R, Shalata A, Sheikh-Ahmad M, Garg A. American journal of medical genetics. Part A. 2017; 173:190-194.

Type 1 Hyperlipoproteinemia Due to Compound Heterozygous Rare Variants in GCKR.
Shetty S, Xing C, Garg A. The Journal of clinical endocrinology and metabolism. 2016; 101:3884-3887.

Exome sequencing reveals novel homozygous FOXE3 mutation in microphthalmos with staphylomatous malformation.
Saboo US, Penke D, Mahindrakar A, Uddaraju M, Sankurathri C, Gong X, Xing C, Mootha VV. Ophthalmic genetics. 2016; 37:1-3.

MicroRNA-21 Aggravates Cyst Growth in a Model of Polycystic Kidney Disease.
Lakhia R, Hajarnis S, Williams D, Aboudehen K, Yheskel M, Xing C, Hatley ME, Torres VE, Wallace DP, Patel V. Journal of the American Society of Nephrology : JASN. 2016; 27:2319-30.

Mitotic Checkpoint Regulators Control Insulin Signaling and Metabolic Homeostasis.
Choi E, Zhang X, Xing C, Yu H. Cell. 2016; 166:567-81.

Type 1 hyperlipoproteinemia in a child with large homozygous deletion encompassing GPIHBP1.
Patni N, Brothers J, Xing C, Garg A. Journal of clinical lipidology. 2016; 10:1035-1039.e2.

Whole-exome sequencing identifies ADRA2A mutation in atypical familial partial lipodystrophy.
Garg A, Sankella S, Xing C, Agarwal AK. JCI insight. 2016; 1:e86870.

A comprehensively characterized cell line panel highly representative of clinical ovarian high-grade serous carcinomas.
Thu KL, Papari-Zareei M, Stastny V, Song K, Peyton M, Martinez VD, Zhang YA, Castro IB, Varella-Garcia M, Liang H, Xing C, Kittler R, Milchgrub S, Castrillon DH, Davidson HL, Reynolds CP, Lam WL, Lea J, Gazdar AF. Oncotarget.  In press

ΔNp63α induces the expression of FAT2 and Slug to promote tumor invasion.
Dang TT, Westcott JM, Maine EA, Kanchwala M, Xing C, Pearson GW. Oncotarget. 2016; 7:28592-611.

Epigenetic inheritance of telomere length obscures identification of causative PARN locus.
Xing C, Garcia CK. Journal of medical genetics. 2016; 53:356-8.

DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesis.
Starokadomskyy P, Gemelli T, Rios JJ, Xing C, Wang RC, Li H, Pokatayev V, Dozmorov I, Khan S, Miyata N, Fraile G, Raj P, Xu Z, Xu Z, Ma L, Lin Z, Wang H, Yang Y, Ben Amitai D, Orenstein N, Mussaffi H, Baselga E, Tadini G, Grunebaum E, Sarajlija A, Krzewski K, Wakeland EK, Yan N, de la Morena MT, Zinn AR, Burstein E. Nature immunology. 2016; 17:495-504.

Suppression of the SWI/SNF Component Arid1a Promotes Mammalian Regeneration.
Sun X, Chuang JC, Kanchwala M, Wu L, Celen C, Li L, Liang H, Zhang S, Maples T, Nguyen LH, Wang SC, Signer RA, Sorouri M, Nassour I, Liu X, Xu J, Wu M, Zhao Y, Kuo YC, Wang Z, Xing C, Zhu H. Cell stem cell. 2016; 18:456-66.

Correlation of Severity of Fuchs Endothelial Corneal Dystrophy With Triplet Repeat Expansion in TCF4.
Soliman AZ, Xing C, Radwan SH, Gong X, Mootha VV. JAMA ophthalmology. 2015; 133:1386-91.

Adult-onset liver disease and hepatocellular carcinoma in S-adenosylhomocysteine hydrolase deficiency.
Stender S, Chakrabarti RS, Xing C, Gotway G, Cohen JC, Hobbs HH. Molecular genetics and metabolism. 2015; 116:269-74.

Hypoxia fate mapping identifies cycling cardiomyocytes in the adult heart.
Kimura W, Xiao F, Canseco DC, Muralidhar S, Thet S, Zhang HM, Abderrahman Y, Chen R, Garcia JA, Shelton JM, Richardson JA, Ashour AM, Asaithamby A, Liang H, Xing C, Lu Z, Zhang CC, Sadek HA. Nature. 2015; 523:226-30.

Intersection of DNA privacy and whole-genome sequencing.
Hong C, Wang J, Xing C, Hwang TH, Park JY. Clinical chemistry. 2015; 61:900-2.

Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening.
Stuart BD, Choi J, Zaidi S, Xing C, Holohan B, Chen R, Choi M, Dharwadkar P, Torres F, Girod CE, Weissler J, Fitzgerald J, Kershaw C, Klesney-Tait J, Mageto Y, Shay JW, Ji W, Bilguvar K, Mane S, Lifton RP, Garcia CK. Nature genetics. 2015; 47:512-7.

Transethnic replication of association of CTG18.1 repeat expansion of TCF4 gene with Fuchs' corneal dystrophy in Chinese implies common causal variant.
Xing C, Gong X, Hussain I, Khor CC, Tan DT, Aung T, Mehta JS, Vithana EN, Mootha VV. Investigative ophthalmology & visual science. 2014; 55:7073-8.

Genome-wide association analysis of radiation resistance in Drosophila melanogaster.
Vaisnav M, Xing C, Ku HC, Hwang D, Stojadinovic S, Pertsemlidis A,Abrams JM. PloS one. 2014; 9:e104858.

De novo heterozygous FBN1 mutations in the extreme C-terminal region cause progeroid fibrillinopathy.
Garg A, Xing C. American journal of medical genetics. Part A. 2014; 164A:1341-5.

Enhancing the power to detect low-frequency variants in genome-wide screens.
Lin CY, Xing G, Ku HC, Elston RC, Xing C. Genetics. 2014; 196:1293-302.

Hereditary lung cancer syndrome targets never smokers with germline EGFR gene T790M mutations.
Gazdar A, Robinson L, Oliver D, Xing C, Travis WD, Soh J, Toyooka S, Watumull L, Xie Y, Kernstine K, Schiller JH. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 2014; 9:456-63.

A novel de novo KIF21A mutation in a patient with congenital fibrosis of the extraocular muscles and Möbius syndrome.
Ali Z, Xing C, Anwar D, Itani K, Weakley D, Gong X, Pascual JM, Mootha VV. Molecular vision. 2014; 20:368-75.

Association and familial segregation of CTG18.1 trinucleotide repeat expansion of TCF4 gene in Fuchs' endothelial corneal dystrophy.
Mootha VV, Gong X, Ku HC, Xing C. Investigative ophthalmology & visual science. 2014; 55:33-42.

Eating disorder predisposition is associated with ESRRA and HDAC4 mutations.
Cui H, Moore J, Ashimi SS, Mason BL, Drawbridge JN, Han S, Hing B, Matthews A, McAdams CJ, Darbro BW, Pieper AA, Waller DA, Xing C, Lutter M. The Journal of clinical investigation. 2013; 123:4706-13.

A novel germline mutation in BAP1 predisposes to familial clear-cell renal cell carcinoma.
Farley MN, Schmidt LS, Mester JL, Peña-Llopis S, Pavia-Jimenez A, Christie A, Vocke CD, Ricketts CJ, Peterson J, Middelton L, Kinch L, Grishin N, Merino MJ, Metwalli AR, Xing C, Xie XJ, Dahia PL, Eng C, Linehan WM, Brugarolas J. Molecular cancer research : MCR. 2013; 11:1061-71.

Homozygosity mapping identifies a bile acid biosynthetic defect in an adult with cirrhosis of unknown etiology.
Molho-Pessach V, Rios JJ, Xing C, Setchell KD, Cohen JC, Hobbs HH. Hepatology (Baltimore, Md.). 2012; 55:1139-45.