1. O'Brien AD, et al (1980) Genetic control of susceptibility to salmonella typhimurium in mice: Role of the LPS gene. J Immunol 124: 20-24.

2. O'Brien AD, Rosenstreich DL & Taylor BA (1980) Control of natural resistance to salmonella typhimurium and leishmania donovani in mice by closely linked but distinct genetic loci. Nature 287: 440-442.

3. Beutler B, Mahoney J, Le Trang N, Pekala P & Cerami A (1985) Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells. J Exp Med 161: 984-995.

4. Beutler B, et al (1985) Identity of tumour necrosis factor and the macrophage-secreted factor cachectin. Nature 316: 552-554.

5. Beutler B, Milsark IW & Cerami AC (2008) Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin. science, 1985, 229(4716):869-871. classical article. J Immunol 181: 7-9.

6. Poltorak A, et al (1998) Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene. Science 282: 2085-2088.

7. Beutler B, et al (2006) Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large. Annu Rev Immunol 24: 353-389.

8. Hoebe K, et al (2003) Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature 424: 743-748.

9. Hoebe K, et al (2005) CD36 is a sensor of diacylglycerides. Nature 433: 523-527.

10. Tabeta K, et al (2006) The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via toll-like receptors 3, 7 and 9. Nat Immunol 7: 156-164.

11. Jiang Z, et al (2006) Details of toll-like receptor:Adapter interaction revealed by germ-line mutagenesis. Proc Natl Acad Sci U S A 103: 10961-10966.

12. Jiang Z, et al (2005) CD14 is required for MyD88-independent LPS signaling. Nat Immunol 6: 565-570.

13. Crozat K, et al (2006) Analysis of the MCMV resistome by ENU mutagenesis. Mamm Genome 17: 398-406.

14. Croker BA, et al (2008) Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger. Proc Natl Acad Sci U S A 105: 15028-15033.

15. Gavin AL, et al (2006) Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling. Science 314: 1936-1938.

16. Janssen E, et al (2006) Efficient T cell activation via a toll-interleukin 1 receptor-independent pathway. Immunity 24: 787-799.

17. Arnold CN, et al (2012) A forward genetic screen reveals roles for nfkbid, Zeb1, and Ruvbl2 in humoral immunity. Proc Natl Acad Sci U S A

18. Du X, et al (2008) The serine protease TMPRSS6 is required to sense iron deficiency. Science 320: 1088-1092.

19. Blasius AL, et al (2011) Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype. Proc Natl Acad Sci U S A 108: 19413-19418.

20. Du X, et al (2008) A catechol-O-methyltransferase that is essential for auditory function in mice and humans. Proc Natl Acad Sci U S A 105: 14609-14614.