Selected Publications for John Abrams, Ph.D.

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Journal Cover

p53 activity is selectively licensed in the Drosophila stem cell compartment
Wylie A, Lu WJ, D'Brot A, Buszczak M, Abrams JM Elife 2014 3 e01530.

A p53 enhancer region regulates target genes through chromatin conformations in cis and in trans.
Link N, Kurtz P, O'Neal M, Garcia-Hughes G, Abrams JM Genes Dev. 2013 Nov 27 22 2433-8.

Tango7 directs cellular remodeling by the Drosophila apoptosome.
D'Brot A, Chen P, Vaishnav M, Yuan S, Akey CW, Abrams JM Genes Dev. 2013 Aug 27 15 1650-5.

Meiotic recombination provokes functional activation of the p53 regulatory network.
Lu WJ, Chap, J, Roig I, Abrams JM. Science June 2010 328 1278-81.

Genome-wide silencing captures obligate apoptotic components in Drosophila.
Chew, S,Chen P, Link, N, Galindo, K, Pogue K. and Abrams JM. Nature July 2009 460 123-127.

A collective form of cell death requires homeodomain interacting protein kinase.
Link, N, Chen P, Lu WJ, Pogue K, Chuong A, Mata M, Checketts J, Abrams JM. J. Cell Biol August 2007 4 (178) 567-74.

p53 directs focused genomic responses in Drosophila.
Akdemir F, Christich A, Sogame N, Chapo J, and Abrams JM. Oncogene February 2007.

Autophagy occurs upstream or parallel to the apoptosome during histolytic cell death.
Akdemir F, Farkas R, Chen P, Juhasz G, Medvedova L, Sass M, Wang L, Wang X, Chittaranian S, Gorski SM, Rodriguez A, Abrams JM Development 2006 133 1457-65.

The apical caspase dronc governs programmed and unprogrammed cell death in Drosophila.
Chew S, Akdemir F, Chen PW, Mills K, Daish T, Kumar S, Rodriguez A, and Abrams JM. Developmental Cell December 2004 Volume 7 897-907.

Drosophila p53 preserves genomic stability by regulating cell death.
Sogame N, Kim M, Abrams JM Proc. Natl. Acad. Sci. U.S.A. 2003 Apr 100 8 4696-701.