Chandrashekhar Pasare, PhD

Assistant Professor
Endowed Title: Louise W. Kahn Scholar in Biomedical Research 2007-2011
Immunology
Graduate Program: Immunology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-648-7322
Office Fax: 214-648-7331

chandrashekhar.pasare@utsouthwestern.edu

Education

Graduate SchoolNational Institute of Immunology, New Delhi, India (1999)

Research Interests

Dendritic Cell Biology
Host-Pathogen Interactions
TLRs and adaptive immunity
Toll-like receptor signaling

Publications

Featured
Priming Microenvironments Dictate Cytokine Requirements for T Helper 17 Cell Lineage Commitment.

Hu W, Troutman TD, Edukulla R, Pasare C, Immunity, 2011 Nov;

Featured
Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt.

Troutman TD, Hu W, Fulenchek S, Yamazaki T, Kurosaki T, Bazan JF, Pasare C, Proceedings of the National Academy of Sciences of the United States of America, 2011 Dec;

Featured
Control of B-cell responses by Toll-like receptors.

Pasare C, Medzhitov R, Nature, 2005 Nov; 438 (7066):364-8

Featured
Toll-dependent control mechanisms of CD4 T cell activation.

Pasare C, Medzhitov R, Immunity, 2004 Nov; 21 (5):733-41

Featured
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells.

Pasare C, Medzhitov R, Science (New York, N.Y.), 2003 Feb; 299 (5609):1033-6

Toll-like receptors: linking innate and adaptive immunity.

Pasare C, Medzhitov R, Advances in experimental medicine and biology, 2005 ; 560:11-8

Toll-like receptors and acquired immunity.

Pasare C, Medzhitov R, Seminars in immunology, 2004 Feb; 16 (1):23-6

Toll-like receptors: linking innate and adaptive immunity.

Pasare C, Medzhitov R, Microbes and infection / Institut Pasteur, 2004 Dec; 6 (15):1382-7

Toll-like receptors: balancing host resistance with immune tolerance.

Pasare C, Medzhitov R, Current opinion in immunology, 2003 Dec; 15 (6):677-82

Honors/Awards

U.T. Southwestern Endowed Scholar in Biomedical Research

(2007)