Margaret Schwarz, MD

Associate Professor
Pediatrics
Graduate Program: Integrative Biology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

margaret.schwarz@utsouthwestern.edu

To make an appointment, call 214-730-KIDS (5437).

Education

FellowshipChildren's Hospital of Pittsburgh (1993)
ResidencyChildren's Hospital - Columbus (1990)
InternshipChildren's Hospital - Columbus (1988)
Medical SchoolUniversity of Missouri - Kansas City (1987)

Research Interests

angiogenesis
extracellular matrix
pancreatic cancer
pulmonary development
vasculature

Publications

Featured
Emerging Pulmonary Vasculature Lacks Fate Specification.

Schwarz, MA, Caldwell, L., Cafasso, D., and Zheng, H , Am J Physiol Lung Cell Mol Physiol. , January 2009; (296(1):):L71-81

Featured
Endothelial-Monocyte Activating Polypeptide (EMAP) II, a novel antitumor cytokine that suppresses primary and metastatic tumor growth, and induces apoptosis in growing endothelial cells.

Schwarz MA, Kandel, J., Brett, G., Li, J., Hayward, J., Schwarz, RE, Chappey, O., Wautier, J., Chabot, J., Lo Gerfo, P., and Stern, D.; , J. Exp. Med. , 1999; (190(3):):341-354

Featured
Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide.

Schwarz, M.A., Lazo, J.S., Yalowich, J.C., Allen, W.P., Whitmore, M., Bergonia, H., Tzeng, E., Billiar, T., Robbins, P., Lancaster, J.R., and Pitt, B.R , Pro. Nat. Acad. Sci. , 1995; (vol. 92):4452-4456

Featured
Cytoplasmic metallothionein overexpression protects NIH3T3 cells from tert-Butyl Hydroperoxide toxicity.

Schwarz, M., Lazo, J.S. Yalowich, J., Reynolds, I., Kagan, V., Tyurin, V., Kim, Y-M., Watkins, S., and Pitt, B. , J. Biol. Chem. , 1994; (269(21):):15238-43

Featured
Epithelial-mesenchymal interactions are linked to neovascularization.

Schwarz, MA, Wan, ZS, Lui, J. and Lee, MK , Am J Respir Cell Mol Biol. , June 2004; (30(6):):784-92

Anti-tumor Effects of EMAP II against Pancreatic Cancer through inhibition of Fibronectin-Dependent Proliferation.

Schwarz, RE, Conduri, S., Awasthi, N., Caldwell, L., Cafasso, D., and Schwarz, MA , Cancer Biol Ther. , April 2010; (20;9(8)):1-8

Schwarz, MA, Zheng, H., Legan, S., and Foty, RA, Lung Self-Assembly is Modulated by Tissue Surface Tensions

Schwarz, MA, Zheng, H., Legan, S., and Foty, RA , Am J Resp Mol Biol. , 2010; (epub)

Lung Self-Assembly is Modulated by Tissue Surface Tensions

Schwarz, MA, Zheng, H., Legan, S., and Foty, RA , Am J Resp Mol Biol. , 2010; (epub)

Emerging Pulmonary Vasculature Lacks Fate Specification.

Schwarz, MA, Caldwell, L., Cafasso, D., and Zheng, H , Am J Physiol Lung Cell Mol Physiol. , January 2009; (296(1)):L71-81

Endothelial Monocyte Activating Polypeptide II interferes with VEGF induced angiogenesis signaling.

Awasthti, N., Schwarz, MA, Varma, V., Cappiello, C., and Schwarz, RE , Lab Invest. , January 2009; (89(1)):38-46

Honors/Awards

Member, NIH NHLBI RIBT Study Section

(2005)

AOA

(2003)

Dr. Edward Livingston Trudeau Scholar from the American Lung Association

(1998)

AHA Clinician Scientst Award

(1992)