Kim Yancey, MD

Professor & Chairman
Endowed Title: Mary Kay Inc. Distinguished Chair in Dermatology
Dermatology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-645-2400

kim.yancey@utsouthwestern.edu

To make an appointment, call 214-645-8300.

Biography

Dr. Kim B. Yancey is Professor and Chair of the Department of Dermatology at the University of Texas Southwestern Medical Center in Dallas. He graduated from the University of Georgia (Summa Cum Laude and Valedictorian), and earned his Medical Degree (Alpha Omega Alpha) from the Medical College of Georgia. Dr. Yancey performed residency training at the Medical College of Georgia and subsequently completed a postdoctoral fellowship in immunodermatology in the Dermatology Branch of the National Cancer Institute at the National Institutes of Health. Dr. Yancey is certified by the American Board of Dermatology, and, in addition, holds special competence in dermatologic immunology and diagnostic laboratory immunology. In 1985, Dr. Yancey joined the faculty of the Uniformed Services University of Health Sciences in Bethesda, Maryland as an Assistant Professor of Dermatology. In 1987, he was promoted to Associate Professor; from 1990-1993 he served as Acting Chairman of this department. In 1993, Dr. Yancey joined the Dermatology Branch of National Cancer Institute as a tenured Senior Investigator at the National Institutes of Health (NIH). His NIH laboratory focused on mechanisms of keratinocyte adhesion to epidermal basement membrane and the pathophysiologic basis of autoimmune and inherited blistering diseases. Between 2001 and 2006, Dr. Yancey served as Professor and Chair of the Department of Dermatology at the Medical College of Wisconsin (MCW). His time was spread among clinical, teaching, research, and administrative responsibilities at MCW, Froedtert Hospital, and the Zablocki Veterans Affairs Medical Center. He was an active member of the Executive Committee of Medical College Physicians between 2004 and 2006, and served as Chair of this body between 2004 and 2005. In 2007, Dr. Yancey was appointed Professor and Chair of the Department of Dermatology at the University of Texas Southwestern Medical Center in Dallas. His professional efforts include basic research, clinical care, various educational programs, and departmental administrative activities. Dr. Yancey is a member of the American Society for Clinical Investigation, the Society for Investigative Dermatology, the American Academy of Dermatology, the American Dermatological Association, and numerous other professional organizations. He is a former Director and Vice President of the American Board of Dermatology, a current member of the Board of Directors and Executive Committee of the Society for Investigative Dermatology, and several editorial boards. In 2007, he received the American Academy of Dermatology’s Marion Sulzberger Award. He has published numerous research manuscripts, monographs, and chapters, served on an array of grant review panels, and presented over 100 scientific abstracts and invited lectures in the U.S. and abroad. He has held research support from the National Institutes of Health for over twenty years.

Education

FellowshipNational Institutes of Health (1985)
ResidencyMedical College of Georgia (1981)
InternshipMedical College of Georgia (1979)
Medical SchoolMedical College of Georgia (1978)

Research Interests

Animal models of skin diseases
Autoimmune blistering diseases
Inherited blistering diseases ie bullosa, epidermolysis

Publications

Featured
The pathophysiology of autoimmune blistering diseases.

Yancey, K.B. , J. Clin. Invest. , 2005; (115):825-828

Featured
Revertant mosaicism: partial correction of a germline mutation in COL17A1 by a frame restoring mutation.

Darling, T.N., Yee, C., Bauer, J.W., Hintner, H., Yancey, K.B. , J. Clin. Invest. , 1999; (103):1371-1377

Featured
Autoreactive CD4+ T-cell responses to the extracellular domain of bullous pemphigoid antigen 2 (BPAG2) in patients with bullous pemphigoid.

Budinger, L., Borradori, L., Yee, C., Merk, H.F., Yancey, K.B., Hertl, M. , J. Clin. Invest. , 1998; (102):2082-2089

Featured
Passive transfer of anti-laminin 5 antibodies induces subepidermal blisters in neonatal mice.

Lazarova, Z., Yee, C., Darling, T., Briggaman, R.A., Yancey, K.B. , J. Clin. Invest. , 1996; (98):1509-1518

Featured
Epiligrin, the major human keratinocye intergrin ligand, is the target of disease in both an acquired autoimmune and an inherited subepidermal blistering skin disease.

Domloge-Hultsch, N., Gammon, W.R., Briggaman, R.A., Gil, S.G., Carter, W.G., Yancey, K.B. , J. Clin. Invest. , 1992; (90):1628-1633

Hair follicle stem cells provide a functional niche for melanocyte stem cells.

Tanimura, S., Tadokoro, Y., Inomata, K., Binh, N.T., Nishie, W., Yamazaki, S., Nakauchi, H., Tanaka, Y., McMillan, J.R., Sawamura, D., Yancey, K., Shimizu, H., Nishimura, E.K. , Cell Stem Cell , 2011; (8):177-187

Sequential intramolecular epitope spreading of humoral responses to human BPAG2 in a transgenic model.

Di Zenzo, G., Calabresi, V., Olasz, E.O., Zambruno, G., Yancey, K.B. , J. Invest. Dermatol. , 2010; (130):1040-1047

Transient Anti-CD40L Co-Stimulation Blockade Prevents Immune Responses against Human Bullous Pemphigoid Antigen 2: Implications for Gene Therapy.

Lanschuetzer, C.M., Olasz, E.B., Lazarova, Z., Yancey, K.B. , J. Invest. Dermatol. , 2009; (129):1203-1207

Human bullous pemphigoid antigen 2 in transgenic skin elicits specific IgG in wild type mice.

Olasz, E., Roh, J.Y., Yee, C., Arita, K., Akiyama, M., Shimizu, H., Vogel, J.C., Yancey, K.B. , J. Invest. Dermatol. , 2007; (127):2807-2817

Humanization of autoantigen.

Nishie, W., Sawamura, D., Goto, M., Ito, K., Shibaki, A., McMillian, J.R., Sakai, K., Nakamura, H., Olasz, E., Yancey, K.B., Akiyama, M., Shimizu H. , Nature Medicine , 2007; (13):378-383

Honors/Awards

Board of Directors, Dermatology Foundation (2008 to date)

(2011)

Executive Committee of Clinical Chairs, UTSW (2009 to date)

(2011)

Deputy Editor, Journal of Investigative Dermatology, (2007-2010)

(2010)

Sulzberger Award and Lecture, American Academy of Dermatology

(2007)

Distinguished Service Award, American Board of Dermatology

(2005)

Professional Associations/Affiliations

American Academy of Dermatology

American Association for the Advancement of Science

American Dermatological Association

American Society for Clinical Investigation

Society for Investigative Dermatology