Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice

Fujikawa T, Chuang JC, Sakata I, Ramadori G, Coppari R , PNAS , October 2010; (107/40):17391-6

SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity

Ramadori G, Fujikawa T, Fukuda M, Anderson J, Morgan DA, Mostoslavsky R, Stuart RC, Perello M, Vianna CR, Nillni EA, Rahmouni K, Coppari R , Cell Metabolism , July 2010; (12):78-87

Glucose-sensing by POMC Neurons Regulates Glucose Homeostasis and is Impaired in Obesity

Parton LE*, Ye CP*, Coppari R*, Enriori PJ*, Choi B, Zang CY, Xu C, Vianna CR, Balthasar N, Lee CE, Elmquist JK, Cowley MA, Lowell BB , 2007 , ; (Nature):228-232 *=Equally Contributing Authors

The Hypothalamic Arcuate Nucleus: A Key Site for Mediating Leptin’s Effects on Glucose Homeostasis and Locomotor Activity

Coppari R*., Ichinose M*, Lee CE, Pullen AE, Kenny CD, McGovern RA, Tang V, Liu SM, Ludwig T, Chua JSC, Lowell BB, Elmquist JK , 2005 , ; (Cell Metabolism 1):63-72 *=Equally Contributing Authors

Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice

Fujikawa T, Chuang JC, Sakata I, Ramadori G, Coppari R , PNAS , October 2010; (107/40):17391-6

Brain SIRT1: Anatomical distribution and regulation by energy availability

Ramadori G, Lee CE, Bookout AL, Lee S, Williams KW, Anderson J, Elmquist JK, Coppari R , Journal of Neuroscience , October 2008; (28/40):9989-9996

SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity

Ramadori G, Fujikawa T, Fukuda M, Anderson J, Morgan DA, Mostoslavsky R, Stuart RC, Perello M, Vianna CR, Nillni EA, Rahmouni K, Coppari R , Cell Metabolism , July 2010; (12):78-87

SIRT1 deacetylase in SF1 neurons protects against metabolic imbalance

Ramadori G, Fujikawa T, Anderson J, Berglund ED, Frazao R, Michan S, Vianna CR, Sinclair DA, Elias CF, Coppari R , Cell Metabolism , 2011; (in press)

Glucose-sensing by POMC Neurons Regulates Glucose Homeostasis and is Impaired in Obesity

Parton LE*, Ye CP*, Coppari R*, Enriori PJ*, Choi B, Zang CY, Xu C, Vianna CR, Balthasar N, Lee CE, Elmquist JK, Cowley MA, Lowell BB , 2007 , ; (Nature):228-232 *=Equally contributing Authors