Yang Xie, PhD

Assistant Professor
Department of Clinical Sciences
Graduate Program: Molecular Biophysics

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

yang.xie@utsouthwestern.edu

Education

Graduate SchoolUniversity of Minnesota Central Office

Research Interests

Bayesian Methodology
Bioinformatics
Cancer Epidemiology
Clinical Trails

Publications

Featured
Analysis of Pleiotropic Transcriptional Profiles: a Case Study of DNA Gyrase Inhibition

Jeong KS, Xie Y, Hiasa H and Khodursky AB , PLoS Genetics , September 2006; (9):e152

Featured
Measures of Bayesian learning and identifiability in hierarchical models

Xie Y, Carlin BP , Journal of Statistical Planning and Inference , October 2006; (136):3458-3477

Featured
Robust Gene Expression Signature from Formalin-Fixed Paraffin-Embedded Samples Predicts Prognosis of Non-Small-Cell Lung Cancer Patients.

Xie Y, Xiao G, Coombes K, Behrens C, Solis LM, Raso MG, Girard L, Erickson HS, Roth JA, Heymach JV, Moran C, Danenberg KD, Minna JD, Wistuba II, Clinical cancer research : an official journal of the American Association for Cancer Research, 2011 Jul; :5705-14

Featured
Image-Based Genome-Wide siRNA Screen Identifies Host Factors Involved in Selective Autophagy. Nature, advance online publication, 2011

Orvedahl A, Sumpter R, Xiao G, Ng A, Zou Z, Tang Y, Narimatsu M, Gilpin C, Sun Q, Roth M, Forst C, Wrana J, Zhang Y, Luby-Phelps K, Xavier R, Xie Y, Levine B. , Nature, 2011; 7375 (480):113-117

Featured
Non-small-cell lung cancer mRNA expression signature predicting response to adjuvant chemotherapy.

Xie Y, Minna JD, Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010 Oct; 28 (29):4404-7

Tumor mRNA Expression Profiles Predicting Responses to Chemotherapy

Minna JD, Girard L, Xie, Y , Journal of Clinical Oncology , October 2007; (28):4329 - 4336

Enhanced identification and biological validation of differential gene expression via illumina whole genome expression arrays through the use of the model based background correction methodology.

Ding L, Xie Y, Park S, Xiao G, Story M. , Nucleic Acids Research , May 2008; (36):e58

Incorporating prior information via shrinkage: a combined analysis of genome-wide location data and gene expression data

Xie Y, Pan W, Jeong KS, Khodursky AB , Statistics in Medicine , May 2007; (26):2258-2275

Predicting the future for people with lung cancer.

Xie Y and Minna JD. , Nature Medicine , August 2008; (14):812 - 813

A Nonparametric Empirical Bayes Approach to Joint Modeling Multiple Sources of Genomic Data.

Pan W, Jeong KS, Xie Y, Khodursky AB. , Statistical Sinica , April 2008; (18):709-729

Honors/Awards

Doctoral Dissertation Fellowship

University of Minnesota Graduate School (2006)

Jacob E. Bearman Student Achievement Award

University of Minnesota (2006)

Guanghua Excellent Student Award

Beijing Medical University (1996-1997) (1997)

Outstanding Student of Beijing City

Beijing, China (1997)

Scholarship for Excellent Student

Beijing Medical University (First Prize, 1993-1995) (1995)

Professional Associations/Affiliations

American Statistical Association

International Biometric Society

Society for Clinical Trials