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Juan Pascual, MD, PhD
Neuroscience
Contact Information
UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390
juan.pascual@utsouthwestern.edu
To make an appointment, call 214-645-8300.
Biography
Juan M. Pascual holds appointments to the faculty of the Departments of Neurology and Neurotherapeutics, Physiology and Pediatrics and is Director of the Rare Brain Disorders Clinic and Laboratory. He is also a member of the Division of Pediatric Neurology, of the graduate programs in Neuroscience and Integrative Biology, and of the postgraduate clinical training programs in Neurology, Pediatric Neurology, Pediatrics and Medical Genetics.
Dr. Pascual received his M.D. degree from the Universidad de Granada, Spain (founded in 1526 by Emperor Charles V over the school established by the Nasrid Sultan of Granada in 1349). He received his Ph.D. degree in Molecular Physiology and Biophysics from Baylor College of Medicine in Houston, Texas. His postdoctoral research was conducted at the Center for Molecular Recognition, College of Physicians and Surgeons of Columbia University and, later, at the Colleen Giblin Research Laboratories for Pediatric Neurology at the same institution. He also obtained residency training in Pediatrics at Washington University School of Medicine- St. Louis Children’s Hospital and in Neurology and Pediatric Neurology at the Neurological Institute of New York- Columbia University Medical Center. He received certification in Neurology with Special Qualification in Child Neurology from the American Board of Psychiatry and Neurology.
As a clinician, he specializes in genetic and metabolic diseases of the nervous and neuromuscular systems of infants, children and adults with a particular emphasis on complex diagnostic problems, second opinions for patients visiting from the rest of the U.S. and abroad, and in pilot and national clinical trials. Dr. Pascual has special clinical research expertise in glucose metabolism, mitochondrial and unusual degenerative and multi-organ disorders.
As one of few pediatric neurologists in the nation who is also a laboratory scientist, Dr. Pascual is interested in the molecular mechanisms that cause inherited metabolic and excitability disorders using electrophysiology and nuclear magnetic resonance (MRI) both in human subjects and in models of human diseases. His laboratory is located in the newest biomedical research building (NL) at UT Southwestern and is an integral part of the Department of Neurology and Neurotherapeutics.
An avid reader, speaker and humanist, Dr. Pascual is also interested in metaphysics, epistemology and the philosophy of mind.
Education
| Residency | Columbia Presbyterian Medical Center - NY (2002) |
| Internship | Washington University St. Louis (1999) |
| Graduate School | Baylor College of Medicine (1995) |
| University | Baylor College of Medicine (1995) |
| University | University of Missouri - Kansas City (1991) |
| Medical School | Universidad de Granada (1990) |
Research Interests
Publications
Choi C, Ganji SK, Deberardinis RJ, Hatanpaa KJ, Rakheja D, Kovacs Z, Yang XL, Mashimo T, Raisanen JM, Marin-Valencia I, Pascual JM, Madden CJ, Mickey BE, Malloy CM, Bachoo RM, Maher EA, Nature medicine, 2012 Jan;
Marin-Valencia I, Good LB, Ma Q, Jeffrey FM, Malloy CR, Pascual JM, Journal of neuroscience methods, 2011 Sep;
Pascual JM, Neuroscience letters, 2011 Oct;
Kaufmann P, Engelstad K, Wei Y, Kulikova R, Oskoui M, Sproule DM, Battista V, Koenigsberger DY, Pascual JM, Shanske S, Sano M, Mao X, Hirano M, Shungu DC, Dimauro S, De Vivo DC, Neurology, 2011 Nov; 77 (22):1965-71
Pérez-Dueñas B, Ormazábal A, Toma C, Torrico B, Cormand B, Serrano M, Sierra C, De Grandis E, Marfa MP, García-Cazorla A, Campistol J, Pascual JM, Artuch R, Archives of neurology, 2011 May; 68 (5):615-21
Choi C, Ganji SK, Deberardinis RJ, Dimitrov IE, Pascual JM, Bachoo R, Mickey BE, Malloy CR, Maher EA, Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 2011 Mar; :609-18
Pascual JM, Neuroscience letters, 2011 Jan; 487 (1):1-2
Marin-Valencia I, Roe CR, Pascual JM, Molecular genetics and metabolism, 2010 Sep; 101 (1):9-17
Bushby K, Finkel R, Birnkrant DJ, Case LE, Clemens PR, Cripe L, Kaul A, Kinnett K, McDonald C, Pandya S, Poysky J, Shapiro F, Tomezsko J, Constantin C, Lancet neurology, 2010 Jan; 9 (1)
Bushby K, Finkel R, Birnkrant DJ, Case LE, Clemens PR, Cripe L, Kaul A, Kinnett K, McDonald C, Pandya S, Poysky J, Shapiro F, Tomezsko J, Constantin C, Lancet neurology, 2010 Feb; 9 (2)
Related Links
Books
Pascual JM, De Vivo DC, Lippincott, Williams & Wilkins2009
Pascual JM, W.B. Saunders2007
De Vivo DC, Pascual JM, Wang D, Lippincott, Williams & Wilkins2009
De Vivo DC, Wang D, Pascual JM, Butterworth-Heinemann2008
Pascual JM, Academic Press2007
Pascual JM, Academic Press2007
Pascual JM, Academic Press2007
Pascual JM, Mosby Elsevier2007
Pascual JM, K. Engelstad, D. Wang, D. C. De Vivo, Lippincott, Williams, and Wilkins2002
Pascual JM , In press
Jotterand F, Pascual JM, Sadler, JZ , Cambridge University PressIn press
Pascual JM, Elsevier2011
Pascual JM, DiMauro S, McGraw-Hill2011
Honors/Awards
Académie Européenne des Sciences, des Arts et des Lettres (2010)
Real Academia de Bellas Artes de San Telmo (2010)
Neurobiology of Disease in Children (2009)
Real Academia Española (2004)
Academia Norteamericana de la Lengua Española (2004)