Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility

Hill JW, Elias CF, Fukuda M, Williams KW, Berglund ED, Holland WL, Cho YR, Chuang JC, Xu Y, Choi M, Lauzon D, Lee CE, Coppari R, Richardson JA, Zigman JM, Chua S, Scherer PE, Lowell BB, Bruning JC, Elmquist JK. , Cell Metab , April 2010; (11(4)):286-97

Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons

Williams KW, Margatho LO, Lee CE, Choi M, Lee S, Scott MM, Elias CF, Elmquist JK , J Neurosci , February 2010; (30(7)):2472-9

5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis

Xu Y, Jones JE, Kohno D, Williams KW, Lee CE, Choi MJ, Anderson JG, Heisler LK, Zigman JM, Lowell BB, Elmquist JK , Neuron , November 2008; (60(4)):582-9

Brain SIRT1: anatomical distribution and regulation by energy availability

Ramadori G, Lee CE, Bookout AL, Lee S, Williams KW, Anderson J, Elmquist JK, Coppari R. , J Neurosci , October 2008; (28(40)):9989-96

Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice

Hill JW, Williams KW, Ye C, Luo J, Balthasar N, Coppari R, Cowley MA, Cantley LC, Lowell BB, Elmquist JK. , J Clin Invest , May 2008; (118(5)):1796-805