Jinming Gao, PhD

Professor
Simmons Comprehensive Cancer Center, Pharmacology
Graduate Program: Biological Chemistry
Cancer Biology

Contact Information

UT Southwestern Medical Center
5323 Harry Hines Boulevard
Dallas, Texas 75390

Office Phone: 214-645-6370
Office Fax: 214-645-6347

jinming.gao@utsouthwestern.edu

Biography

Jinming Gao received his BS degree in Chemistry at Peking University (Beijing, China) in June 1991. He came to the US and carried out graduate studies at Harvard University under the supervision of Dr. G. M. Whitesides.  In May 1996, he received a PhD degree in Medicinal Chemistry with thesis research focused on rational drug design and protein charge ladders. Following his doctoral studies, he completed his postdoctoral training in Biomedical Engineering under Dr. R. S. Langer at Massachusetts Institute of Technology.

In August 1998, Dr. Gao joined the faculty of Biomedical Engineering at Case Western Reserve University in Cleveland, Ohio. He was promoted to Associate Professor with tenure in Biomedical Engineering and Radiology in April 2004.  In July 2005, Dr. Gao moved his lab to Dallas, Texas, where he currently holds a primary appointment as Professor (with tenure) of Oncology and Pharmacology in the Simmons Comprehensive Cancer Center at UT Southwestern and a joint appointment in Chemistry and Bioengineering at UT Dallas.

Using a highly-interdisciplinary approach, Dr. Gao's lab is focusing on development of multi-functional nanomedicine platforms that incorporate tumor targeting, imaging ultrasensitivity, and controlled drug release for cancer-targeted therapy.

 

Education

Graduate SchoolHarvard University (1996)

Research Interests

Cancer molecular imaging
Cancer nanomedicine
MRI molecular probes
Polymer biomaterials
Targeted drug delivery

Publications

Featured
Multifunctional Polymeric Micelles as Cancer-Targeted, MRI-Ultrasensitive Drug Delivery Systems

Nasongkla N, Bey EA, Ren J, Ai H, Khemtong C, Setti JG, Chin SF, Sherry AD, Boothman DA, Gao J , Nano Letters , 2006; (6):2427-2430

Featured
cRGD-Functionalized Polymer Micelles for Targeted Doxorubicin Delivery

Nasongkla, N.; Shuai, X.; Ai, H.; Weinberg, B.D.; Pink, J.; Boothman, D.A.; Gao, J. , Angew. Chem. Int. Ed. , 2004; (43/46):6323-6327

Featured
Magnetite-Loaded Polymeric Micelles as Novel Magnetic Resonance Probes

Ai, H.; Flask, C.; Weinberg, R.; Shuai, X.; Pagel, M.; Farrell, D.; Duerk, J.; Gao, J. , Adv. Mater. , 2003; (17):1949-1952

Featured
Functional Arteries Grown in Vitro

Niklason, L.; Gao, J.; Abbott, W.; Hirschi, K.; Houser, S.; Marini, R.; Langer, R. , Science , 1999; (5413/284):489-493

Featured
Evaluating Electrostatic Contributions to Binding with the Use of Protein Charge Ladders

Gao, J.; Mammen, M.; Whitesides, G. M. , Science , 1996; (272/5261):535-537

Beta-Lapachone Micellar Nanotherapeutics for Non-Small Cell Lung Cancer Therapy

Blanco, E.; Bey, E.A.; Khemtong, C.; Yang, S.; Setti-Guthi, J.; Chen, H.; Kessinger, C.; Garnevale, K.; Bornmann, W.; Boothman, D.; Gao, J. , Cancer Res. , 2010; (70):3896-3904

In Vivo Off Resonance Saturation Magnetic Resonance Imaging of alpha(v)beta(3)-Targeted Superparamagnetic Nanoparticles

Khemtong, C.; Kessinger, C.W.; Ren, J.; Bey, E.; Yang, S.G.; Guthi, J.; Boothman, D.A., Sherry, A.D.; Gao, J. , Cancer Res. , 2009; (69):1651-1658

Intratumoral Delivery of beta-Lapachone via Polymer Implants for Prostate Cancer Therapy

Dong, Y.; Chin, S.F.; Blanco, E.; Bey, E.A.; Kabbani, W.; Xie, X.J.; Bornmann, W.G.; Boothman, D.A. Gao, J. , Clin. Cancer Res. , 2009; (15):131-139

Theranostic Nanomedicine for Cancer

Sumer, B.; Gao, J. , Nanomedicine , 2008; (3):137

Honors/Awards

Distinguished Scientist Award

Society of Experimental Biology and Medicine (2011)

Distinguished Overseas Young Scientist

National Natural Science Foundation of China (2007)